| EPH Contractors NW Ltd | Construction | 2017 |
| Epic Furniture Ltd | Wholesale & retail | 2014 |
| Epona Equestrian Ltd | Wholesale & retail | 2025 |
| ER Care Ltd | Health & social care | 2022 |
| ERC Vehicle Services Ltd | Wholesale & retail | 2019 |
| Erinzo IT Services Limited | Information & communication | 2011 |
| Eselkay Limited | Real estate | 2022 |
| ESG Ashtons Limited | Hospitality | 2025 |
| Eternal Synergy Co Ltd | Households | 2023 |
| Eternox UK Ltd | Wholesale & retail | 2025 |
| Ethereal Image Limited | Arts & recreation | 2025 |
| Ethical Trading Limited | Education | 2024 |
| Ethos Collaborative Community Interest Company | Information & communication | 2025 |
| Etras Limited | Financial services | 2008 |
| Eunoia-Living Ltd | Health & social care | 2020 |
| Eunoia-Property Development Ltd | Real estate | 2025 |
| European Essential Supply Ltd | Transport & logistics | 2021 |
| Europlas Ltd | Professional & scientific | 2025 |
| Eurosolve Chemicals Ltd | Manufacturing | 2018 |
| EV Cable Shop Ltd | Wholesale & retail | 2018 |
| EV Charging Posts Limited | Manufacturing | 2012 |
| EV Charging Stations Ltd | Manufacturing | 2017 |
| EVA Bower Ltd | Real estate | 2024 |
| Events With a Difference Ltd | Arts & recreation | 2026 |
| Ever-Evolving Ltd | Education | 2021 |
| Evergreen Assets Ltd | Wholesale & retail | 2023 |
| Everlasting Developments Ltd | Real estate | 2019 |
| Evermast Steel Services Ltd | Construction | 2021 |
| Everyday Vitals Limited | Wholesale & retail | 2024 |
| Everydayz Upland Ltd | Wholesale & retail | 2019 |
| Everyone Matters Schools Trust | Education | 2016 |
| Everythingnatal Ltd | Education | 2021 |
| EVO Logix Systems Limited | Information & communication | 2025 |
| Evoke Care Premium Ltd | Information & communication | 2026 |
| Evolution Developments NW Limited | Construction | 2020 |
| Evolution Fitness XL Limited | Arts & recreation | 2021 |
| Evolution Massage Ltd | Other services | 2025 |
| Evolution Supplements Ltd | Wholesale & retail | 2021 |
| Excellence Health Care Professionals Limited | Administrative & support | 2022 |
| Excellent Choice Roofing & Cladding Ltd | Water & waste | 2026 |
| Exmed Investments Limited | Financial services | 2021 |
| Expert Exteriors Landscaping Specialists Ltd | Administrative & support | 2022 |
| Express Car Wash ST Helens Ltd | Other services | 2023 |
| Express Parcels UK Ltd | | 2009 |
| Express Pulse Logistics Ltd | Transport & logistics | 2024 |
| EYE Wala Ltd | Wholesale & retail | 2006 |
| EZEE2SELL Ltd | Wholesale & retail | 2025 |
| Ezeecopy Limited | Professional & scientific | 1986 |
| F Luxury Store Limited | Wholesale & retail | 2017 |
| F T Electrical (NW) Limited | Construction | 2018 |
| F.A. Schwarz Limited | Wholesale & retail | 1976 |
| Fabfashion Supply Ltd | Wholesale & retail | 2025 |
| Fairbreak Holdco Limited | Financial services | 2025 |
| Fairbreak Limited | Wholesale & retail | 2002 |
| Fairfield Community Fund | Health & social care | 1973 |
| Fairhurst Property Maintenance Ltd | Administrative & support | 2024 |
| Fairview Care & Support Ltd | Health & social care | 2021 |
| Fairway Financing Limited | Administrative & support | 2025 |
| Faith Hope Love Ltd | Manufacturing | 2022 |
| Faith Pharma Trading Limited | Real estate | 2012 |
| Faith Pharmacy Limited | Wholesale & retail | 2005 |
| Faiva Property Investments Ltd | Real estate | 2024 |
| Faiva Property Services Ltd | Extraterritorial | 2024 |
| Falano Limited | Hospitality | 2018 |
| Fama Transporting Ltd | Transport & logistics | 2021 |
| Family Liaison Professionals Ltd | Public administration | 2010 |
| Fanmar Transport Ltd | Transport & logistics | 2024 |
| Fanning & Co Limited | Professional & scientific | 2023 |
| Farleys Chemist Ltd | Wholesale & retail | 2016 |
| Farnworth 2000 Limited | Wholesale & retail | 2000 |
| Farrelly Accountancy Services Limited | Professional & scientific | 2024 |
| Fast M Motors Ltd | Wholesale & retail | 2026 |
| Fast Track Imaan Healthcare Ltd | Wholesale & retail | 2024 |
| Fastech & Co Ltd | Manufacturing | 2012 |
| Fastlane Autocare Ltd | Wholesale & retail | 2021 |
| FC ST Helens Community CIC | Arts & recreation | 2019 |
| Fedenni Assists Limited | Real estate | 2024 |
| Felgoron Installare Ltd | Manufacturing | 2025 |
| Feraz Limited | Wholesale & retail | 2009 |
| Ferguson & Partners Limited | Professional & scientific | 2015 |
| Fernandez Medical Limited | Health & social care | 2023 |
| Ferndown Healthcare Limited | Wholesale & retail | 2024 |
| Ferny Knoll Stud Limited | Education | 2015 |
| Ferraro Cosmetics Ltd | Wholesale & retail | 2024 |
| Ferrybridge Healthcare Limited | Wholesale & retail | 2023 |
| Ferton Properties Ltd | Administrative & support | 2019 |
| FFF Ryan Derbyshire Limited | Arts & recreation | 2024 |
| FFP Limited | Financial services | 2004 |
| FH Housing Limited | Real estate | 2017 |
| FID Best Trans Ltd | Transport & logistics | 2025 |
| Field Investment Holdings Ltd | Real estate | 2020 |
| Fielding Leisure Limited | Health & social care | 2009 |
| Fifteen Sixteen Ltd | Wholesale & retail | 2024 |
| Fighting Malaria in Children Ltd | Health & social care | 2023 |
| Fika Automation Solutions Ltd | Professional & scientific | 2024 |
| Film & Foil Solutions Limited | Manufacturing | 2008 |
| Final Impact Comics Ltd | Information & communication | 2022 |
| Finchy’S Memorials Ltd | Wholesale & retail | 2025 |
| Find ME a Printer Limited | Manufacturing | 2026 |
| Fine Line Body Repairs Ltd | Wholesale & retail | 2021 |