| DL Accounts Ltd | Professional & scientific | 2014 |
| DL Mortgages Ltd | Financial services | 2022 |
| DN Solutions Limited | Administrative & support | 2011 |
| Double Edged Ltd | Professional & scientific | 2024 |
| Double Luck Inn Limited | Hospitality | 2021 |
| Downwest Embroidery Ltd | Manufacturing | 2023 |
| Dowrick Holdings Limited | Financial services | 2024 |
| Dowrick Properties Limited | Real estate | 2025 |
| Dreckley Consulting Ltd | Professional & scientific | 2019 |
| Drinana Limited | Hospitality | 1978 |
| Drivegerman Ltd | Wholesale & retail | 2025 |
| DSL Electrical Install Limited | Construction | 2016 |
| Dual Vision Coaching and Mentoring Ltd | Professional & scientific | 2022 |
| Dubs Locked-In Limited | Information & communication | 2026 |
| Duchy Chef Ltd | Hospitality | 2017 |
| Duchy Network Solutions Ltd | Information & communication | 2010 |
| Duchy Solutions Limited | Professional & scientific | 2026 |
| Duchy Transport & Services Ltd | Transport & logistics | 2006 |
| Dutch Flower Import South West Limited | Wholesale & retail | 2011 |
| Dyer Construction Cornwall Ltd | Construction | 2018 |
| E & a (Cornwall) Ltd | Hospitality | 2024 |
| E & M Tiling Ltd | Construction | 2018 |
| E & T Food Ltd | Hospitality | 2025 |
| Easebourne Trust | Real estate | 2007 |
| East Road Limited | Hospitality | 2019 |
| Ebron Tech Ltd | Manufacturing | 2019 |
| Eco Dragon (South West) Ltd | Construction | 2012 |
| Eco Incentives Limited | Extraterritorial | 2007 |
| ED Faull Stone Masons Ltd | Construction | 2014 |
| Eddystone Electrical Ltd | Construction | 2024 |
| Eden Bathrooms Ltd | Households | 2017 |
| Eden Construction & Swimming Pools Ltd | Construction | 2023 |
| Eden Harbour Construction Ltd | Construction | 2022 |
| Eden Harbour Limited | Real estate | 2021 |
| Eden Living Cornwall Limited | Wholesale & retail | 2025 |
| Edgcumbe Rise Flats Management Company Limited | Households | 2005 |
| Edge-Edge Plastering Limited | Construction | 2017 |
| Edible ST Austell CIC | Arts & recreation | 2022 |
| EEZ Drylining Ltd | Construction | 2021 |
| Eight Grey Limited | Arts & recreation | 2006 |
| EIGHTY-6 Nail and Spa Ltd | Other services | 2024 |
| EIGHTY-6 Property Ltd | Real estate | 2024 |
| Electrical Solutions 2014 Limited | Construction | 2014 |
| Elephant Brain Ltd | Extraterritorial | 2011 |
| Elite Eight Barbering Co Ltd | Other services | 2025 |
| Elite Gardening Limited | Administrative & support | 2026 |
| ELP Energy Ltd | Wholesale & retail | 2022 |
| Elyn Bres Limited | Health & social care | 2018 |
| Emlee Ltd | Wholesale & retail | 2019 |
| Employee Technology Solutions Ltd | Information & communication | 2025 |
| Engineering Inspection Solutions Limited | Administrative & support | 2010 |
| Engraving Purrfection Ltd | Wholesale & retail | 2024 |
| Entidex Ltd | Information & communication | 2026 |
| Environmental Hazards Management Association Ltd | Professional & scientific | 2018 |
| Equinoxx Ltd | Information & communication | 2010 |
| Ernest Ireland Properties (South West) Limited | Financial services | 1938 |
| ESR Property Services Ltd | Real estate | 2024 |
| Essco Contracting Services Ltd | Construction | 2024 |
| Essential Elements Limited | Professional & scientific | 2003 |
| Essential Golf Equipment Ltd | Wholesale & retail | 2025 |
| Etab Mada Ltd | Real estate | 2020 |
| Ethical Energy Developments Ltd | Energy | 2012 |
| Ethical Renewable Developments LLP | | 2012 |
| Evely's Classic Garage Limited | Wholesale & retail | 2018 |
| Eventcuisine@Best. Limited | Hospitality | 1999 |
| Eventide (Hayle) Management Company Ltd | Households | 2025 |
| Evident Digital Group Limited | Professional & scientific | 2015 |
| Evolution Impact Ltd | Professional & scientific | 2019 |
| EW Cornwall Limited | Hospitality | 2023 |
| Ewpm Ltd | Construction | 2024 |
| Exclusive GAS Ltd | Construction | 2020 |
| Exhale Cigarettes Ltd | Other services | 2011 |
| Exoteric Ltd | Wholesale & retail | 2017 |
| Ezonecornwall Limited | Manufacturing | 2022 |
| F&S Electrical Contractors Ltd | Construction | 2011 |
| F.A.O. Business Support Services Ltd | Administrative & support | 2025 |
| FAC Properties Limited | Real estate | 2008 |
| FAC Property Consultants Limited | Real estate | 2008 |
| Factsandtales Limited | Professional & scientific | 2024 |
| Faizan Properties Limited | Real estate | 2024 |
| Fancy Fit Ltd | Manufacturing | 2019 |
| Farley Reach Residents Limited | Extraterritorial | 2018 |
| Fast FIX Hydraulics Ltd | Professional & scientific | 2025 |
| FBG Solutions Limited | Professional & scientific | 2022 |
| Feock Fields Management Company Limited | Households | 2010 |
| FGH (Lanhydrock) Ltd | Financial services | 2017 |
| FH 88 Limited | Hospitality | 2022 |
| Fiberlean Technologies Limited | Manufacturing | 2016 |
| Figure 8 Consulting Ltd | Professional & scientific | 2022 |
| Financial Ideas Limited | Professional & scientific | 2023 |
| Financial Planning Concepts Limited | Financial services | 2006 |
| Findy Designs Limited | Professional & scientific | 2012 |
| Finest Lodges Limited | Real estate | 2025 |
| Fireshield Compliance Ltd | Professional & scientific | 2026 |
| First AID Awards Limited | Professional & scientific | 2009 |
| First Class Web Design Limited | Information & communication | 2014 |
| First Test Minerals Ltd | Mining & quarrying | 2014 |
| First Wave Adventures Limited | Administrative & support | 2013 |
| Fishmag Ltd | Wholesale & retail | 2022 |
| Fliska Limited | Information & communication | 2022 |