| Philip Gordon Driving Services Limited | Other services | 2007 |
| Pinfold Promotions Limited | Other services | 1996 |
| Pipped at the Post Ltd | Manufacturing | 2025 |
| Pitchr Ltd | Information & communication | 2026 |
| Pleir Management Limited | Professional & scientific | 2019 |
| Polkadot Lettings Ltd | Households | 2022 |
| Pons Pacificus Ltd | Transport & logistics | 2025 |
| Poole's Farms Limited | Agriculture & fishing | 1970 |
| Poplars Advisory Ltd | Professional & scientific | 2024 |
| Post Wizard Limited | Information & communication | 2023 |
| Power Tools Plus Ltd | Wholesale & retail | 2003 |
| Precise Surveys Limited | Professional & scientific | 2013 |
| Pro-Cure Assist Ltd | Construction | 2019 |
| Probuild (East Mids) Limited | Construction | 2010 |
| Property LAB Limited | Extraterritorial | 2014 |
| Quercus Cottage Investments Limited | Real estate | 2019 |
| Quickbits Revival Limited | Wholesale & retail | 2018 |
| Rainbow Takeaway Ltd | Hospitality | 2020 |
| Random Investment Management Ltd | Extraterritorial | 2015 |
| Ravenscroft Securities Limited | Extraterritorial | 1965 |
| RBS Enterprises (Southwell) Ltd | Hospitality | 2017 |
| RD Engineering Consultancy Limited | Professional & scientific | 2021 |
| Reach Learning Disability | Hospitality | 1999 |
| Reach Learning Disability Care C.I.C. | Health & social care | 2011 |
| Reece a Walker Ltd | Professional & scientific | 2021 |
| Regency House Holdings Limited | Construction | 2025 |
| Rizest Limited | Information & communication | 2014 |
| RJB Golf Limited | Wholesale & retail | 2024 |
| RMB Property Group Ltd | Real estate | 2024 |
| Roffe Electrical Ltd | Construction | 2020 |
| Roffe Health, Safety and Consultancy Ltd | Professional & scientific | 2017 |
| Rose and MOO Ltd | Wholesale & retail | 2020 |
| Rufford Advisory Services Limited | Professional & scientific | 2022 |
| S.W. Elliott Limited | Agriculture & fishing | 2016 |
| SA Bookings Ltd | Professional & scientific | 2026 |
| Sage Southwell Limited | Hospitality | 2025 |
| Sally Jensen Consultancy Limited | Hospitality | 2023 |
| Salon 106 Limited | Other services | 2015 |
| Sarah Greaves Limited | Manufacturing | 1997 |
| Saxton Recruitment Ltd | Other services | 2016 |
| SB2 Consultancy Limited | Information & communication | 2010 |
| Schreucor Ltd | Health & social care | 2017 |
| Scope M&E Holdings Ltd | Real estate | 2016 |
| Scope M&E Ltd | Construction | 2016 |
| Scott Dixon Racing Limited | Arts & recreation | 2019 |
| Screen POP Digital Networking Limited | Administrative & support | 2020 |
| Sector Support Limited | Real estate | 2007 |
| Serenity Walks UK Ltd | Health & social care | 2026 |
| Services Limited | Professional & scientific | 1983 |
| Setraining Group Ltd | Education | 2026 |
| Sheriff Enforcer Ltd | Real estate | 2013 |
| Sherwood Ecological Ltd | Professional & scientific | 2024 |
| Sherwood Food & Drink Limited | Manufacturing | 2021 |
| Ship Business Support Services Limited | Professional & scientific | 2014 |
| SID & Betty Ltd | Administrative & support | 2018 |
| Signature Dance Studios Ltd | Education | 2024 |
| Simply Asking Limited | Information & communication | 2024 |
| Sinfiltron Limited | Manufacturing | 1979 |
| Social Panda Limited | Information & communication | 2012 |
| SOURCE4 Bikes Limited | Wholesale & retail | 2004 |
| Southwell Afterschool Club CIC | Arts & recreation | 2010 |
| Southwell and District Funeral Service Ltd | Extraterritorial | 2013 |
| Southwell and Nottingham Diocesan Board of Finance | Administrative & support | 1891 |
| Southwell Cathedral Chapter Trading Limited | Wholesale & retail | 2016 |
| Southwell Framing & Design Limited | Manufacturing | 2015 |
| Southwell Funeral Service Ltd | Extraterritorial | 2013 |
| Southwell Holiday Cottages Ltd | Hospitality | 2016 |
| Southwell Magazines Limited | Information & communication | 2020 |
| Southwell Mobile Solutions Ltd | Manufacturing | 2015 |
| Southwell Music Festival Ltd | Arts & recreation | 2013 |
| Southwell Properties Limited | Real estate | 1988 |
| Southwell Property Services Limited | Administrative & support | 2017 |
| Southwell Spice Club Limited | Hospitality | 2026 |
| Southwell Training Limited | Administrative & support | 2012 |
| Spare Time SEO Ltd | Information & communication | 2023 |
| Sportstar Clothing Limited | Wholesale & retail | 2018 |
| Spotted Dog I T Services Limited | Information & communication | 2014 |
| SSA Medics Limited | Health & social care | 2018 |
| Steve Hines Accountancy Services Ltd | Professional & scientific | 2012 |
| Storage Matters Ltd | Wholesale & retail | 2022 |
| Strive Movement Limited | Health & social care | 2024 |
| Studio Sasha Ltd | Construction | 2022 |
| Studio Seven 8THS Ltd | Professional & scientific | 2019 |
| SUA Property Limited | Real estate | 2026 |
| Sunninghill Off-Licence Limited | Wholesale & retail | 2013 |
| Sustainable Constructs Ltd | Construction | 2025 |
| Swift Estate Planning Services Limited | Information & communication | 2015 |
| Synk Global Ltd | Professional & scientific | 2025 |
| T Broughton Ventures Ltd | Administrative & support | 2026 |
| T V NIX Builders Property Limited | Real estate | 2022 |
| T1 Accountancy and Taxation Services Ltd | Professional & scientific | 2011 |
| Tassprotect Ltd | Households | 2025 |
| Tawlon Properties Limited | Real estate | 2022 |
| TCH Medical Limited | Health & social care | 2022 |
| Teal and Logan Interiors Ltd | Wholesale & retail | 2026 |
| Teal Processes Ltd | Information & communication | 2026 |
| Team 7 Racing Limited | Education | 2015 |
| Teiri Consultancy Ltd | Professional & scientific | 2023 |
| Temple Courts Investments Limited | Extraterritorial | 1955 |
| Tenham Electrical Engineers Limited | Extraterritorial | 1972 |