| Ybennett Ltd | Transport & logistics | 2025 |
| Yearforward Property Management Limited | Households | 1990 |
| Yellow Rose Healthcare Limited | Health & social care | 2020 |
| Yellow Sales Limited | Professional & scientific | 2022 |
| Yellow Top Holdings Limited | Transport & logistics | 2022 |
| Yellow Top Taxis Limited | Transport & logistics | 2019 |
| YEW Tree Livery Limited | Agriculture & fishing | 2024 |
| Yirse Limited | Information & communication | 2015 |
| YLC Investments Limited | Real estate | 2015 |
| YLC Services Limited | Other services | 2016 |
| YLO Ltd | Manufacturing | 2017 |
| YN Foods Ltd | Hospitality | 2026 |
| Yogabyrose Ltd | Health & social care | 2018 |
| Yoganjali Limited | Wholesale & retail | 2020 |
| York Homes (NW) 2 Limited | Construction | 2019 |
| York Manor Flat Management Limited | Households | 2003 |
| York Mobility (Hire & Sales) Limited | Administrative & support | 2015 |
| Young Housing Ltd | Real estate | 2025 |
| Your C.A.R.E Group NW Ltd | Administrative & support | 2025 |
| Your Strategies for Success Ltd | Professional & scientific | 2015 |
| Yphysios Ltd | Health & social care | 2024 |
| YS Loughborough Limited | Hospitality | 2019 |
| YTK Enterprise Limited | Health & social care | 2017 |
| YUE Hing 888 Ltd | Hospitality | 2023 |
| Z Y Tradings Ltd | Wholesale & retail | 2014 |
| Zackspek Enterprises Limited | Professional & scientific | 1990 |
| Zazo Property Ltd | Real estate | 2024 |
| ZDH Limited | Real estate | 2020 |
| ZED Starr Communications Ltd | Professional & scientific | 2018 |
| ZEN Garden Landscapes Ltd | Construction | 2022 |
| ZEN Motion Ltd | Professional & scientific | 2026 |
| Zenbros Ltd | Hospitality | 2023 |
| Zenith Art Limited | Wholesale & retail | 2010 |
| Zenith Retail UK Ltd | Wholesale & retail | 2026 |
| Zentex Limited | Wholesale & retail | 2010 |
| Zenzele Ltd | Health & social care | 2012 |
| Zeroarena Limited | Information & communication | 1995 |
| Zeta (Mercury) Limited | Administrative & support | 2024 |
| Zetland Court (122, Manchester RD.) Management Co. Limited | Households | 1995 |
| Zeus Ecosphere Limited | Information & communication | 2018 |
| Zeustone Limited | Manufacturing | 2017 |
| ZF Takeaway Ltd | Hospitality | 2022 |
| Zhongnelson Limited | Manufacturing | 2015 |
| Zifo Technologies Ltd | Information & communication | 2012 |
| ZIG Zags @ ST Patricks Limited | Other services | 2006 |
| Ziggy Art Limited | Wholesale & retail | 2004 |
| Ziicabs Ltd | Transport & logistics | 2026 |
| Zinnia Books UK Limited | Information & communication | 2015 |
| Zips & Snips Ltd | Wholesale & retail | 2010 |
| ZOE True Interiors Limited | Real estate | 2022 |
| Zopp Industries Limited | Professional & scientific | 2017 |
| Zumex Medical Services Ltd | Health & social care | 2010 |
| Zuzu Alterations Ltd | Administrative & support | 2024 |
| Zuzu Kirkby Ltd | Other services | 2025 |
| Zuzu Sewing and Ironing Company Limited | Other services | 2013 |
| ZX Properties Ltd | Real estate | 2024 |
| Zzajump Ltd | Wholesale & retail | 2024 |
| Zzars Solutions Ltd | Transport & logistics | 2021 |