| First Class Finance Limited | Financial services | 2015 |
| First Point Healthcare Services PVT Limited | Health & social care | 2019 |
| Fisher & Clarke Property Development Ltd | Construction | 2024 |
| Fisher Commercial Construction Ltd | Construction | 2018 |
| Fisher Specialist Construction Ltd | Construction | 2022 |
| Fisher Williams Limited | Professional & scientific | 2026 |
| Fishface Seafood Ltd | Wholesale & retail | 2012 |
| Fishguard Close Management (15-22) RTM Company Limited | Households | 2020 |
| Fishkeeping News Limited | Other services | 2019 |
| Fitton Estates Limited | Real estate | 2011 |
| Fitton Estates.Com Ltd | Real estate | 2008 |
| Fitzhenry Properties Limited | Real estate | 2015 |
| Five Star Holidays Limited | Administrative & support | 2014 |
| Five Star Ventilation Supplies Ltd | Construction | 2017 |
| FKJ Medical Services Limited | Health & social care | 2013 |
| FL Limited | Manufacturing | 2025 |
| Flash Business Solutions Ltd | Wholesale & retail | 2018 |
| Flavorloop Limited | Hospitality | 2024 |
| Flavourfresh Salads Limited | Agriculture & fishing | 1997 |
| Flavours the Real Ice Cream Company Limited | Professional & scientific | 1988 |
| Fleets Services Ltd | Other services | 2022 |
| Fleming Johnson Construction Limited | Construction | 2026 |
| Fletcher Healthcare Northwest CIC | Health & social care | 2026 |
| Fletcher Homes NW Ltd | Construction | 2022 |
| Fletchers Fabrics Ltd | Wholesale & retail | 2026 |
| Fleur Grace Limited | Arts & recreation | 2021 |
| Flex OFF Licence Limited | Wholesale & retail | 2023 |
| Flexcom IT Limited | Extraterritorial | 2018 |
| Flexi-Agent Auctions Limited | Real estate | 2024 |
| Flexi-Agent Lettings Ltd | Real estate | 2022 |
| Flexi-Agent Limited | Real estate | 2019 |
| Flexible Procurement Services Limited | Information & communication | 2007 |
| FLG Services Ltd | Manufacturing | 2026 |
| FLIGHT22@THEGOLFCAFE Ltd | Hospitality | 2024 |
| Flint Construction Services Limited | Construction | 2023 |
| Flint Developments Southport Limited | Real estate | 2024 |
| Flint Roofing Southport Limited | Construction | 2019 |
| Floofsters UK Ltd | Professional & scientific | 2021 |
| Flooring Enterprises Limited | Financial services | 2019 |
| Flooring UK Online Ltd | Wholesale & retail | 2022 |
| Flowerstyle Events Ltd | Other services | 2022 |
| FM Active Ltd | Real estate | 2023 |
| FN Bromborough Limited | Arts & recreation | 2025 |
| FN Southport Limited | Arts & recreation | 2024 |
| Fn.Movis Ltd | Professional & scientific | 2014 |
| Focus Legal Training and Compliance Limited | Professional & scientific | 2019 |
| Focus Technology Solutions Limited | Information & communication | 2020 |
| Fofo and Fomo Media Productions Limited | Information & communication | 2025 |
| Foleus Ltd | Information & communication | 2026 |
| Fones and Computing Formby Ltd | Other services | 2022 |
| Fones and Computing Tarleton Ltd | Other services | 2022 |
| Food 4 Soil Ltd | Water & waste | 2023 |
| Food and Chef Limited | Hospitality | 2024 |
| Food Plus Southport Limited | Wholesale & retail | 2025 |
| Foodtech Design and Build Ltd | Construction | 2008 |
| Footwell Podiatry Ltd | Health & social care | 2025 |
| Fore Financial Planning Ltd | Financial services | 2024 |
| Fore Partner Support Services Ltd | Administrative & support | 2025 |
| Forest Hill Developments (NW) Ltd | Construction | 2018 |
| Forest Hill Developments Ltd | Construction | 2018 |
| Forever Property Limited | Households | 2013 |
| Forever Together CIC | Education | 2023 |
| Forgan Distillery Limited | Manufacturing | 2025 |
| Forged Solutions Ltd | Information & communication | 2025 |
| Form Commercial & Advisory Services Ltd | Professional & scientific | 2025 |
| Formby Block Paving Limited | Construction | 2002 |
| Formby Day Nursery Limited | Education | 2003 |
| Formby Dental Laboratory Ltd. | Manufacturing | 2005 |
| Formby Fabrications Limited | Manufacturing | 2018 |
| Formby Foot Golf Ltd | Arts & recreation | 2015 |
| Formby Gold Valeting Ltd | Administrative & support | 2026 |
| Formby M.O.T. and Service Centre Limited | Wholesale & retail | 1989 |
| Formby Timber Supplies Limited | Manufacturing | 1981 |
| Formby Trading Limited | Wholesale & retail | 2006 |
| Formuone Limited | Hospitality | 2022 |
| Forpanic Ltd | Transport & logistics | 2025 |
| Forshaw Building Contractors Ltd | Construction | 2017 |
| Forshaws Accountants Limited | Professional & scientific | 2012 |
| Fortanach & Fortune Ltd | Construction | 2022 |
| Forty Seven Ovington Ltd | Hospitality | 2020 |
| Forward Defence Limited | Professional & scientific | 2017 |
| Forward Property Solutions Limited | Real estate | 2003 |
| Forward Training & Development Limited | Administrative & support | 2009 |
| Foster Construction (NW) Ltd | Construction | 2021 |
| Found a Brand Limited | Manufacturing | 2026 |
| Fountains Grosvenor Management Limited | Households | 1999 |
| Four Seasons (NW) Ltd | Administrative & support | 2017 |
| FR33M3N Limited | Information & communication | 2022 |
| Frakar. Ltd | Health & social care | 2016 |
| Fran's Little Learners Limited | Health & social care | 2026 |
| Francis Freeman Associates Limited | Professional & scientific | 2016 |
| Frandalz Limited | Real estate | 2024 |
| Franklyn Court (Management Company) Limited | Households | 1993 |
| Frasers Heavy Contracting Ltd | Transport & logistics | 2026 |
| Free Motor Legal Limited | Other services | 2012 |
| Freelance Finance Services Ltd | Professional & scientific | 2024 |
| Freight Hunter Ltd | Transport & logistics | 2012 |
| Fresh Food Hub Ltd | Extraterritorial | 1982 |
| Fresh Grill Inn Ltd | Manufacturing | 2019 |
| Fresh Install Limited | Extraterritorial | 2013 |