| Domus BIO Ltd | Wholesale & retail | 2014 |
| Domus Versus Ltd | Construction | 2015 |
| Donas Security Limited | Administrative & support | 2013 |
| Donclints Healths World Ltd | Health & social care | 2016 |
| Doonamis Boutiques Ltd | Wholesale & retail | 2025 |
| Doonamis Limited | Wholesale & retail | 2015 |
| Doortrace Limited | Hospitality | 2019 |
| Dovaston Law Limited | Professional & scientific | 2021 |
| Dove Homes Ltd | Hospitality | 2023 |
| Dovecote Park (Minster Lovell) Management Company Limited | Households | 2019 |
| Dovely Homes C.I.C. | Health & social care | 2023 |
| Dowling Consultants Limited | Professional & scientific | 2006 |
| Downer & Co. Associates Limited | Professional & scientific | 2008 |
| DPL Advisory Services Limited | Information & communication | 2020 |
| DPW Property Services Ltd | Real estate | 2025 |
| DQP Ltd | Real estate | 2014 |
| DR Ahmed Oncology Ltd | Professional & scientific | 2015 |
| DR Barbara Ltd | Health & social care | 2014 |
| DR Donna Arya Ltd. | Health & social care | 2015 |
| DR Gleb Ivanov Limited | Health & social care | 2010 |
| DR SR ROY GP Ltd | Health & social care | 2022 |
| Drayton Mews Freehold Limited | Households | 2015 |
| Dream Giveaways Limited | Wholesale & retail | 2026 |
| Drei-Build LLP | | 2018 |
| Driven Automotive Consulting Limited | Professional & scientific | 2020 |
| Driving Staffing Solutions Ltd | Administrative & support | 2025 |
| Drkley Limited | Construction | 2017 |
| Drovers Court (Micklefield) Management Company Limited | Households | 2019 |
| Drummer Bees Ltd | Manufacturing | 2022 |
| Drurycourt Property Limited | Real estate | 2009 |
| DRW FM Consulting Limited | Professional & scientific | 2020 |
| DS Developments Ltd | Real estate | 2025 |
| DSL Consultants Limited | Information & communication | 1981 |
| DSMN8 Ltd | Information & communication | 2016 |
| Dsquare Services Ltd | Real estate | 2016 |
| DSS Estates PVT Ltd | Real estate | 2019 |
| DTF Warehouse Ltd | Wholesale & retail | 2026 |
| DTP Educational Consultants Ltd | Education | 2026 |
| DTS Catering Group Limited | Hospitality | 2024 |
| Duafort Limited | Wholesale & retail | 2023 |
| Dubuy Ltd | Professional & scientific | 2023 |
| Dude Startup Ltd | Wholesale & retail | 2023 |
| Due-Diligence.Consulting Limited | Professional & scientific | 2018 |
| Duehl Ltd | Households | 2021 |
| Duenas Consulting Ltd | Professional & scientific | 2024 |
| Dugganite Racing Limited | Administrative & support | 2018 |
| Dukan 1 Ltd | Water & waste | 2021 |
| Duncan Grieve Ltd | Arts & recreation | 2022 |
| Dune Solutions Ltd | Wholesale & retail | 2021 |
| Dunes Investments Limited | Professional & scientific | 2017 |
| Dunhill Aviation Ltd | Transport & logistics | 2020 |
| Dunhill Aviation Services Ltd | Transport & logistics | 2025 |
| Dunphy Automation Services Limited | Information & communication | 2024 |
| Duobuild Solutions Ltd | Real estate | 2024 |
| Dust to Done Cleaning Limited | Administrative & support | 2026 |
| Duty by Design Limited | Construction | 2015 |
| Dvan Autos MOT 1 Limited | Wholesale & retail | 2019 |
| Dvan Autos Services 1 Limited | Wholesale & retail | 2019 |
| DWK Building Services Ltd | Construction | 2019 |
| Dynamic Production Services Ltd | Construction | 2009 |
| Dynamic Roofs Ltd | Construction | 2025 |
| Dynisty Services Ltd | Administrative & support | 2026 |
| DZ Plumbing and Heating Limited | Construction | 2023 |
| E & R Acquisitions Limited | Real estate | 2024 |
| E & R Digital Solutions Limited | Information & communication | 2024 |
| E a K Services Limited | Professional & scientific | 2011 |
| E Bedini & Sons Limited | Manufacturing | 2003 |
| E E Carpets & Flooring Ltd | Construction | 2024 |
| E K Nguyen Limited | Real estate | 2025 |
| E&B Mechanics Limited | Wholesale & retail | 2019 |
| E&B Motors Limited | Wholesale & retail | 2018 |
| E&B Renovations Ltd | Construction | 2022 |
| E.C.K.N. Properties Limited | Construction | 1977 |
| E.K.S. Electrical Limited | Professional & scientific | 2022 |
| E.K.S. Property Maintenance Limited | Construction | 2018 |
| E.S.M Parts & Automotive Ltd | Wholesale & retail | 2025 |
| E20 Investments Ltd | Administrative & support | 2022 |
| Eagle Heights Properties Limited | Real estate | 2022 |
| Earthworm Developments Limited | Construction | 2011 |
| East Essex Foot Care Ltd | Health & social care | 2016 |
| East Gate (Wantage) Management Company Limited | Households | 2019 |
| East India Traders Ltd | Hospitality | 2025 |
| East West Army Surplus Ltd | Wholesale & retail | 2013 |
| Eastern Beavers Limited | Construction | 2010 |
| Eastern Security Ltd | Administrative & support | 2001 |
| Eastfield Moda Ltd | Wholesale & retail | 2024 |
| Eastwood Air Services Limited | Manufacturing | 2020 |
| Eastwood Hall Limited | Hospitality | 1985 |
| Eastwood Motor Company UK Limited | Administrative & support | 2010 |
| Eastwood Plant Hire Ltd | Administrative & support | 2021 |
| Eastwood Tree Services Ltd | Agriculture & fishing | 2019 |
| Easwood Services Ltd | Manufacturing | 2009 |
| Easylet Limited | Extraterritorial | 1959 |
| Eatalia (Thorpe Bay) Limited | Hospitality | 2025 |
| Eazystore Ltd | Transport & logistics | 2012 |
| Eazzzibaby Limited | Other services | 2025 |
| EB Ultrasound Limited | Health & social care | 2020 |
| EC2I Limited | Manufacturing | 2001 |
| Echoes of the Mind Ltd | Other services | 2025 |
| ECJ Service Solutions Limited | Administrative & support | 2025 |