| Exclusively Weddings Ltd | Wholesale & retail | 2009 |
| Exdell Limited | Professional & scientific | 2023 |
| Exec Search Ltd | Administrative & support | 2025 |
| Executive Career Jump Limited | Administrative & support | 2018 |
| Executive Dwellings Limited | Real estate | 2024 |
| Executive Securities Personnel Ltd | Administrative & support | 2015 |
| Executive Thinking Ltd | Extraterritorial | 2024 |
| Executive Travel New Forest Limited | Transport & logistics | 2025 |
| Executivego Ltd | Administrative & support | 2019 |
| Executives Ride Limited | Transport & logistics | 2020 |
| Exeter Park Road Limited | Real estate | 2023 |
| Exgrange Ltd | Households | 2025 |
| Exgrange Property Management Ltd | Households | 2026 |
| Exile Gym Ltd | Arts & recreation | 2011 |
| Exile MMA Members Ltd | Arts & recreation | 2020 |
| EXL Project Management Ltd | Professional & scientific | 2020 |
| Exley Design & Planning Ltd | Professional & scientific | 2016 |
| Exmoor Rock Ltd | Hospitality | 2025 |
| Exodus Orbitals Ltd | Manufacturing | 2018 |
| Exordia Limited | Construction | 2021 |
| Exotic NSS Ltd | Administrative & support | 2016 |
| Expand Group AI Limited | Information & communication | 2025 |
| Expandify Commerce Ltd | Wholesale & retail | 2026 |
| Expedient Healthcare Services Limited | Administrative & support | 2017 |
| Expedient Limited | Professional & scientific | 2017 |
| Expedite Projects Ltd | Wholesale & retail | 2022 |
| Experience Attraction Technologies Ltd | Information & communication | 2023 |
| Expert Construct Limited | Construction | 2017 |
| Expert Server Limited | Information & communication | 1989 |
| Experts Live UK Ltd | Administrative & support | 2024 |
| Explorative Limited | Information & communication | 2018 |
| Exploreco Limited | Hospitality | 2025 |
| Expo (Drills) Limited | Administrative & support | 1971 |
| Expo Manager Solutions Limited | Information & communication | 2024 |
| Expobeacon Limited | Information & communication | 2023 |
| Express Eats Catering Ltd | Hospitality | 2022 |
| Express Finance Loans Limited | Financial services | 2002 |
| Express Ironing Southampton Ltd | Other services | 2017 |
| Express Marine Repair Services Ltd | Manufacturing | 2020 |
| Express the Bunker Ltd | Wholesale & retail | 2025 |
| Express Weldcare Services Limited | Wholesale & retail | 2001 |
| Exquisite Chef Group Limited | Hospitality | 2021 |
| Extended Family Ltd | Professional & scientific | 2007 |
| Extension Design Building Plans Limited | Professional & scientific | 2017 |
| External Insulation and Rendering Ltd | Construction | 2024 |
| External Professional Support Limited | Professional & scientific | 1999 |
| Exton Equine Essentials Ltd | Other services | 2025 |
| Extra Seven Limited | Financial services | 2006 |
| Extra-Easy Solutions Ltd | Wholesale & retail | 2024 |
| Extreme Construction South Ltd | Construction | 2025 |
| Extreme Electronics and Accessories Ltd | Wholesale & retail | 2014 |
| Extreme Marine Ltd | Manufacturing | 1999 |
| Extreme Plastering Ltd | Construction | 2014 |
| Extreme Signs Ltd | Manufacturing | 2005 |
| Extreme Trailers Ltd | Manufacturing | 2011 |
| EYE Scope Tech Limited | Wholesale & retail | 2023 |
| Eyes 4 Deals Ltd | Real estate | 2019 |
| Eyes on Limited | Professional & scientific | 2010 |
| Eyeslices UK Limited | Wholesale & retail | 2015 |
| EZ FIX Paintless Dent Removal Ltd | Wholesale & retail | 2019 |
| Ezgi HSE Consulting Limited | Professional & scientific | 2021 |
| Ezra Logistic Ltd | Transport & logistics | 2024 |
| Ezyweb Ltd | Information & communication | 1994 |
| Ezzy FIX Ltd | Construction | 2016 |
| E’Clips Hair and Beauty Lounge Ltd | Other services | 2026 |
| F & K Signs Ltd | Manufacturing | 2009 |
| F & M Engineering Ltd | Construction | 2010 |
| F A-Akb Ltd | Transport & logistics | 2024 |
| F G Cardiac Services Limited | Health & social care | 2025 |
| F Karimi Ltd | Health & social care | 2021 |
| F Noble & Sons Limited | Construction | 2011 |
| F One Technologies Ltd | Wholesale & retail | 2013 |
| F S S W Ltd | Construction | 1946 |
| F&A Associates Ltd | Professional & scientific | 2018 |
| F&L Interiors Limited | Construction | 2018 |
| F&L Speed Ltd | Transport & logistics | 2023 |
| F&R Taxis Ltd | Transport & logistics | 2026 |
| F&T Property (Southampton) Ltd | Construction | 2025 |
| F-V Production Limited | Arts & recreation | 2025 |
| F. E. Chase and SON Limited | Construction | 1984 |
| F. Properties Limited | Real estate | 2002 |
| F.G. Precision Limited | Manufacturing | 1980 |
| F.G. Property Consulting Ltd | Other services | 2009 |
| F.H. Hale & Sons (Builders) Limited | Real estate | 1959 |
| F.O.I.T Ltd | Information & communication | 2017 |
| F.R.C Ltd | Health & social care | 2026 |
| F1 Marine Limited | Professional & scientific | 2015 |
| F171 Services Limited | Professional & scientific | 2022 |
| FAB U FAB Limited | Hospitality | 2026 |
| Faba Umbrella Services Limited | Administrative & support | 2025 |
| Fabrication Technologies Limited | Manufacturing | 2022 |
| Fabrics. Gold Trading Ltd | Wholesale & retail | 2018 |
| Fabsteelrm Ltd | Manufacturing | 2024 |
| Fabulous Beauty & Hair Limited | Wholesale & retail | 2015 |
| Fabulous Partners Limited | Hospitality | 2024 |
| Face Dermals Limited | Health & social care | 2013 |
| Face Homes Ltd | Real estate | 2021 |
| Faces | | 2004 |
| Facilities Maintenance Contracts Limited | Manufacturing | 2011 |
| Facilitypro Academy Ltd | Administrative & support | 2023 |