| Emma Marston Hair Limited | Other services | 2018 |
| Emma Nails 18 Ltd | Other services | 2018 |
| Emma Scott Beauty Ltd | Other services | 2022 |
| Emma Turner Communications Limited | Administrative & support | 2024 |
| Emmachris Holdings Limited | Transport & logistics | 2019 |
| Emmanuil Limited | Administrative & support | 2025 |
| Emmanuil NB Ltd | Administrative & support | 2025 |
| Emmas Flowers Ltd | Wholesale & retail | 2022 |
| Emons Indian Takeaway Ltd | Hospitality | 2022 |
| Emotionslock Ltd | Wholesale & retail | 2026 |
| EMP Partnership Limited | Professional & scientific | 2023 |
| Empath-E Limited | Information & communication | 2003 |
| Empath-E Services Limited | Information & communication | 2010 |
| Emphasis Event Production Limited | Administrative & support | 2006 |
| Empire Electrical & Mechanical Solutions Ltd | Construction | 2020 |
| Empire H Ltd | Wholesale & retail | 2024 |
| Empire Hill Estates Ltd | Real estate | 2018 |
| Empire Leisure Events Ltd | Professional & scientific | 2024 |
| Empire Property and Development Ltd | Construction | 2023 |
| Empire Stores Ltd | Wholesale & retail | 2025 |
| Empire Times Ltd | Wholesale & retail | 2024 |
| Emplacement Ltd | | 2003 |
| Employee Relations Services Ltd | Administrative & support | 2018 |
| Empower Blue Ltd | Wholesale & retail | 2024 |
| Empower Property Maintenance Ltd | Construction | 2020 |
| Empowr Personal Training Ltd | Education | 2024 |
| Empress Accounting Ltd | Professional & scientific | 2023 |
| Empress Developments Ltd. | Wholesale & retail | 2014 |
| Empress Heights RTM Company Limited | Households | 2014 |
| Empress Sony Retail Ltd | Wholesale & retail | 2024 |
| Empress Way Management Company Limited | Households | 2019 |
| Emsan Renovations Ltd | Real estate | 2023 |
| Emscote Mill Residents Ltd | Real estate | 2021 |
| EMU Build and Clean Ltd | Construction | 2022 |
| EMU Interior Design Ltd | Professional & scientific | 2012 |
| Emulate Ltd | Information & communication | 2025 |
| EMW Logistic Limited | Transport & logistics | 2014 |
| EMZ Beauty Ltd | Other services | 2025 |
| EN Route Logistics Ltd | Transport & logistics | 2016 |
| ENA Chinese Wellbeing Salon Ltd | Health & social care | 2020 |
| Enablement Homes Limited | Real estate | 2016 |
| ENB Oncology Ltd | Health & social care | 2025 |
| END to END Logistics Ltd | Administrative & support | 2023 |
| END Zone KIT Ltd | Wholesale & retail | 2020 |
| Endangered Asian Species Trust | Professional & scientific | 2003 |
| Endeavour Close Management Company Limited | Households | 2014 |
| Endeavour Communication Solutions Limited | Health & social care | 2016 |
| Endeavour OV RTM Company Limited | Households | 2024 |
| Endeavour Recruitment Solutions Limited | Administrative & support | 2013 |
| Enden Mechanical Ltd. | Manufacturing | 2015 |
| Enderland Ltd | Transport & logistics | 2016 |
| Endgame Capital Limited | Real estate | 2020 |
| Endgame Estates Limited | Professional & scientific | 2020 |
| Endgame Rebuild Limited | Construction | 2024 |
| Endon Limited | Households | 1996 |
| Endorphin Software Limited | Information & communication | 1994 |
| Enenco Office Design and Development Limited | Construction | 2022 |
| Energee Ltd. | Education | 2023 |
| Energetic Shield Ltd | Other services | 2026 |
| Energetic Wisdom Ltd | Health & social care | 2022 |
| Energi EV Solutions Limited | Professional & scientific | 2024 |
| Energi Solutions Limited | Construction | 2022 |
| Energise Sports Limited | Arts & recreation | 2023 |
| Energised Project Solutions Ltd | Professional & scientific | 2022 |
| Energize-Uk Limited | Arts & recreation | 2023 |
| Energy Bill Solutions Limited | Energy | 2025 |
| Energy Management Limited | Professional & scientific | 2020 |
| Energy Management Products Ltd | Manufacturing | 2008 |
| Energy Recovery Solutions Limited | Construction | 2013 |
| Energy Water Limited | Financial services | 2024 |
| Energy World International Limited | Extraterritorial | 2017 |
| ENERGY101 Ltd | Professional & scientific | 2021 |
| Enfields Commercial Limited | Real estate | 2008 |
| Enfields Vincent Limited | Real estate | 2008 |
| Engage Financial Solutions Ltd | Financial services | 2021 |
| Engage Intelligently Ltd | Professional & scientific | 2025 |
| Engaging Data Limited | Information & communication | 2018 |
| Engine Recon Limited | Wholesale & retail | 2018 |
| Engine Refurb UK Limited | Manufacturing | 2025 |
| Engine Restore Ltd | Wholesale & retail | 2024 |
| Engineering Consultancy Limited | Professional & scientific | 2004 |
| Engineering Holdings Limited | Financial services | 2017 |
| Engineering Talent Ltd | Administrative & support | 2026 |
| Englex Limited | Information & communication | 2007 |
| English Rose Travel Company Limited | Administrative & support | 1996 |
| Englyst Carbohydrates Limited | Professional & scientific | 1998 |
| Engraved Memories Ltd | Manufacturing | 2021 |
| Engtex Consulting Limited | Professional & scientific | 2012 |
| Enhance Glazing and Property Services Ltd | Construction | 2016 |
| Enhance Hair & Beauty Southampton Limited | Other services | 2022 |
| Enhanced Care Services Ltd | Health & social care | 2015 |
| Enhanced Computer Solutions Holdings Limited | Professional & scientific | 2007 |
| Enhanced Computer Solutions Limited | Information & communication | 1994 |
| Enhanced Photonics Limited | Professional & scientific | 2008 |
| Enigmatica AI Ltd | Information & communication | 2024 |
| Enitor Properties Limited | Real estate | 2023 |
| Enitor Rentals Ltd | Real estate | 2025 |
| ENJ8YED Limited | Professional & scientific | 2008 |
| Enjoy Fitness Limited | Arts & recreation | 2025 |
| Enle Business Services Limited | Information & communication | 2025 |