| Vagman Ltd | Wholesale & retail | 2025 |
| Vail Williams Employment Services Limited | Administrative & support | 1995 |
| Vail Williams LLP | | 2006 |
| Vaisoft Technologies Ltd | Information & communication | 2008 |
| Valentine Court (Southampton) Management Company Limited | Households | 1997 |
| Valentino Nails 3 Ltd | Other services | 2022 |
| Valentino Services Ltd | Transport & logistics | 2017 |
| Valeting Centre Limited | Professional & scientific | 2016 |
| Valetoria Ltd | Manufacturing | 2025 |
| Valico Publishing Ltd | Wholesale & retail | 2023 |
| Valiha Consultancy Ltd | Information & communication | 2019 |
| Valkyrie Consultants Group Ltd | Professional & scientific | 2023 |
| Valkyrie Health & Fitness Ltd | Arts & recreation | 2025 |
| Valler Newco Limited | Hospitality | 2025 |
| Valley Control Systems Ltd | Professional & scientific | 2021 |
| Valley Law Limited | Professional & scientific | 2004 |
| Valley Mini Market Ltd | Wholesale & retail | 2026 |
| Valley Place (Surbiton) Management Co. Limited | Households | 1981 |
| Valley Ventures Limited | Administrative & support | 2016 |
| Valley View Management (Southampton) Limited | Households | 1987 |
| Valley View Stud Ltd | Agriculture & fishing | 2008 |
| Valluvanadu Limited | Hospitality | 2024 |
| Valmora Services Ltd | Administrative & support | 2025 |
| Valor Asset Management Limited | Real estate | 2025 |
| Valor Associates Limited | Professional & scientific | 2020 |
| Valor Holding Companies Limited | Administrative & support | 2020 |
| Valvecon Limited | Administrative & support | 2018 |
| Vama Properties Limited | Real estate | 2025 |
| Vama Spa Limited | Other services | 2022 |
| Vamp Marine Limited | Construction | 2021 |
| Vancouver Property Company Limited | Real estate | 1922 |
| Vandikaran.Uk. Ltd | Wholesale & retail | 2024 |
| Vanguard Cold Storage & Distribution Limited | Transport & logistics | 2019 |
| Vanguard Estates & Holdings Ltd | Financial services | 2026 |
| Vanguard Maritime Solutions Ltd | Professional & scientific | 2023 |
| Vanguard Number 1 Limited | Real estate | 2017 |
| Vanguard PFP & Joinery Ltd | Construction | 2019 |
| Vanilla Gourmet Catering Limited | Hospitality | 2004 |
| Vanille Royale Limited | Wholesale & retail | 2025 |
| Vanity Lounge Hair & Beauty Limited | Other services | 2016 |
| Vans 4 Less Limited | Wholesale & retail | 2015 |
| Vans Direct (Southern) Limited | Wholesale & retail | 2003 |
| Vanta Point Ltd | Professional & scientific | 2026 |
| Vantage Clothing Ltd | Wholesale & retail | 2026 |
| Vantage Land, Sea & Sky Limited | Hospitality | 2019 |
| Vantage PUB Company Limited | Hospitality | 2020 |
| Vantora Ltd | Wholesale & retail | 2025 |
| Vape & Smoke Bazaar Ltd | Wholesale & retail | 2021 |
| Vape Escape Southampton Ltd | Wholesale & retail | 2024 |
| Vape Hardware Limited | Manufacturing | 2021 |
| Vape N’ Beans Limited | Hospitality | 2023 |
| Vapess Two U Limited | Wholesale & retail | 2023 |
| Vapetime UK Ltd | Administrative & support | 2012 |
| Vapor-Z Havant Limited | Wholesale & retail | 2013 |
| Vaporz Southampton Limited | Wholesale & retail | 2013 |
| Varese-Secure Ltd | Wholesale & retail | 2015 |
| Varisa Foods Ltd | Hospitality | 2024 |
| Vartex Global Ltd | Information & communication | 2025 |
| Vasi Power Ltd | Professional & scientific | 2023 |
| Vasi Southern Ltd | Professional & scientific | 2019 |
| Vasil Express Ltd | Wholesale & retail | 2024 |
| Vass Homes Ltd | Construction | 2025 |
| Vast XU Limited | Manufacturing | 2025 |
| Vasthomp Limited | Construction | 2022 |
| Vastpoint Ltd | Information & communication | 2025 |
| Vavasi Limited | Transport & logistics | 2020 |
| Vavona Bespoke Joinery Limited | Manufacturing | 2014 |
| Vaxandi Ltd | Administrative & support | 2010 |
| Vaxshan Limited | Wholesale & retail | 2018 |
| Vconsult Limited | Professional & scientific | 2023 |
| VDR Properties (YIG) Limited | Real estate | 2020 |
| Vear Building Services Limited | Construction | 1995 |
| Vear Holdings Limited | Financial services | 1999 |
| Vear M & E Services Limited | Construction | 1995 |
| Veazey Property Developments Ltd | Real estate | 2022 |
| Vectecus Ltd | Construction | 2022 |
| Vectis Financial Services Limited | Financial services | 2014 |
| Vectis Horizon Limited | Construction | 2008 |
| Vectis Land Management Limited | Real estate | 2026 |
| Vector CFO Ltd | Professional & scientific | 2026 |
| Vector Marine Limited | Manufacturing | 2026 |
| Vector Tutoring Ltd | Education | 2025 |
| Vedanshi News Limited | Wholesale & retail | 2017 |
| VEE TAM Limited | Health & social care | 2009 |
| Veeclean Ltd | Administrative & support | 2020 |
| Veescent Candles Ltd | Wholesale & retail | 2025 |
| Vega Apartments Limited | Real estate | 2018 |
| Vega Designs Ltd | Construction | 2019 |
| Vega Recruitment Ltd | Administrative & support | 2020 |
| Vehicle Logistics Company Ltd | Transport & logistics | 2021 |
| Vehicleeye Ltd | Wholesale & retail | 2024 |
| Veho Global Group Limited | Financial services | 2019 |
| Veho UK Ltd | Manufacturing | 2007 |
| Veiga Limited | Information & communication | 2024 |
| Vela Drive Ltd | Transport & logistics | 2024 |
| Vela Projects Ltd | Arts & recreation | 2024 |
| Velara Solutions Ltd | Professional & scientific | 2025 |
| Veles Capital Consulting Ltd | Other services | 2025 |
| Veles Capital Ltd | Other services | 2025 |
| Velion Technology Ltd | Information & communication | 2025 |