| Skrc Integrated Infrastructure Ltd | Construction | 2026 |
| Skwat Fitness Ltd | Arts & recreation | 2019 |
| Sky Building Ltd | Construction | 2015 |
| Sky Delivery Services Limited | Professional & scientific | 2018 |
| Sky Direction Limited | Wholesale & retail | 2024 |
| Sky Global Advisory Limited | Administrative & support | 2022 |
| Sky Lettings 365 Limited | Real estate | 2018 |
| Sky of Waves Ltd | Wholesale & retail | 2025 |
| Sky Pictures Limited | Extraterritorial | 2014 |
| Sky Trans Ltd | Transport & logistics | 2018 |
| Skyblue Transport Ltd | Transport & logistics | 2024 |
| Skye Holiday Lettings Ltd | Real estate | 2022 |
| Skyefit Personal Training Ltd | Health & social care | 2023 |
| Skylandia Consulting Ltd | Information & communication | 2026 |
| Skylark Ascends Limited | Financial services | 2025 |
| Skyline Events & Structures Ltd | Construction | 2026 |
| Skyline Hosting Solutions Limited | Information & communication | 2008 |
| Skyline Roofing & Building Solutions Ltd | Construction | 2025 |
| Skyline Roofing & Maintenance Ltd | Construction | 2025 |
| Skyline School Sports Ltd | Education | 2025 |
| Skylines Air Conditioning Ltd | Construction | 2011 |
| Skymat Limited | Professional & scientific | 2013 |
| Skypath Limited | Administrative & support | 2000 |
| Skysol AI Ltd | Professional & scientific | 2025 |
| Skytouch Buildings Ltd | Construction | 2020 |
| Skyward Commercial Interests Limited | Financial services | 2025 |
| Skywheels Travel Limited | Administrative & support | 2024 |
| Skywire Communications Limited | Information & communication | 2011 |
| SKZ Properties Limited | Real estate | 2022 |
| SL Core Limited | Administrative & support | 2010 |
| SL Private Limited | Wholesale & retail | 2016 |
| SL Trans Ltd | Transport & logistics | 2017 |
| Slawkowskitransport Ltd | Transport & logistics | 2025 |
| Slawomir Stobiecki Limited | Health & social care | 2009 |
| Slcm Business Support Ltd | Administrative & support | 2019 |
| Sleekhounds Ltd | Wholesale & retail | 2022 |
| SLH Contractors Ltd | Construction | 2007 |
| Slice & Bites Soton Limited | Hospitality | 2024 |
| Slim Projects Limited | Professional & scientific | 2020 |
| Slipform Engineering International (2000) Limited | Construction | 2012 |
| Slipstream Management Limited | Administrative & support | 2018 |
| SLK Construction Ltd | Construction | 2012 |
| SLK Property Solutions Ltd | Construction | 2018 |
| Sllh Trans Ltd | Transport & logistics | 2024 |
| SLM Electrics Limited | Energy | 2015 |
| SLM Tutoring Services Limited | Professional & scientific | 2025 |
| SLN Consultancy Ltd | Professional & scientific | 2023 |
| SLN Property Services Ltd | Real estate | 2022 |
| Slotab Ltd | Health & social care | 2014 |
| Slow Alladin Limited | Wholesale & retail | 2026 |
| SLS (Housing Consultants) Limited | Professional & scientific | 2012 |
| SLS Construction (Southern) Ltd | Construction | 2008 |
| SM Finance Lounge Ltd | Financial services | 2022 |
| SM Property Portfolio Ltd | Real estate | 2021 |
| SM Systems Plumbing and Heating Ltd | Construction | 2021 |
| SM5 Developments Ltd | Construction | 2018 |
| SM5 Holdings Limited | Financial services | 2023 |
| SM5 Property Limited | Real estate | 2025 |
| SMA Logistics & Property Maintenance Ltd | Water & waste | 2025 |
| Smac Business Integration Ltd. | Information & communication | 2014 |
| Smac Partnership Ukeig | | 2007 |
| Smae Consulting Limited | Professional & scientific | 2025 |
| Small Animal Clinical Therapies Ltd | Professional & scientific | 2025 |
| Small Car Services Ltd | Wholesale & retail | 2022 |
| Small Enterprises Ltd | Real estate | 2019 |
| Small Steps Giant Leaps Ltd. | Education | 1999 |
| Small Works Property Services Ltd | Construction | 2019 |
| Small World Collaboration Ltd | Information & communication | 2006 |
| Smart Accountancy & Business Consulting Ltd | Professional & scientific | 2019 |
| Smart AI Networks Ltd | Information & communication | 2025 |
| Smart Crafts Supplies Ltd | Manufacturing | 2021 |
| Smart Cutz Barbers Ltd | Other services | 2023 |
| Smart Fabric Inks Limited | Manufacturing | 2011 |
| Smart Fabrications Ltd | Manufacturing | 2026 |
| Smart Farming Solutions Ltd | Professional & scientific | 2023 |
| Smart General Care Ltd | Health & social care | 2025 |
| Smart Insurance Services Limited | Financial services | 2003 |
| Smart Locate Solutions Services Ltd | Professional & scientific | 2026 |
| Smart Meals Limited | Wholesale & retail | 2000 |
| Smart Money Wealth Limited | Administrative & support | 2019 |
| Smart Property Services Hampshire Ltd | Construction | 2026 |
| Smart Repair Shops Limited | Wholesale & retail | 2012 |
| Smart Roofing & Home Improvements Ltd | Construction | 2016 |
| Smart Room Lettings Limited | Real estate | 2015 |
| Smart Rudder Education Ltd | Professional & scientific | 2024 |
| Smart Rudder Online Ltd | Education | 2024 |
| Smart Shipping Services Ltd | Transport & logistics | 2024 |
| Smart Terms Ltd | Financial services | 2023 |
| Smart Way Limited | Transport & logistics | 2019 |
| Smart Window Solutions Ltd | Construction | 2024 |
| Smart Wings Aviation Services Ltd | Transport & logistics | 2021 |
| Smart-Rentals Ltd | Real estate | 2019 |
| Smarta Foods Limited | Wholesale & retail | 2020 |
| Smarta Services Ltd | Administrative & support | 2018 |
| Smartcable Limited | Extraterritorial | 2001 |
| Smartcall Healthcare Solutions Ltd | Administrative & support | 2024 |
| Smartcraft Hub Ltd | Wholesale & retail | 2024 |
| Smarter Business Support Ltd | Professional & scientific | 2022 |
| Smarter Data Management Limited | Information & communication | 1991 |
| Smarthubit Limited | Information & communication | 2017 |