| Ranger Photography Ltd. | Professional & scientific | 2011 |
| Rangers Run Limited | Other services | 2024 |
| Ranking Edge Ltd | Professional & scientific | 2025 |
| Ranya Hair Style Ltd | Other services | 2025 |
| Raoco Ltd | Wholesale & retail | 2024 |
| Rapid Accountants Ltd | Professional & scientific | 2019 |
| Rapid Boiler Repair Ltd | Construction | 2020 |
| Rapid Care Services Ltd | Health & social care | 2022 |
| Rapid Repair Network Limited | Other services | 2017 |
| Rapid Response Services Ltd | Construction | 2004 |
| Rapid Smart Repairs South Ltd | Wholesale & retail | 2026 |
| Rapid Teknology Limited | Information & communication | 2025 |
| Raptor Build Ltd | Construction | 2018 |
| Raptor Drylining Ltd | Construction | 2019 |
| Raquel Campos Regenerative Clinic Ltd | Health & social care | 2022 |
| RAR Retail Ltd | Wholesale & retail | 2024 |
| Rarangi Consultants Limited | Professional & scientific | 2010 |
| Rare Art Press Limited | Information & communication | 2012 |
| Rareridge Investments Limited | Real estate | 2019 |
| Rareridge Limited | Information & communication | 2004 |
| Rascal's Party Shop Limited | Wholesale & retail | 2026 |
| Rascals Castles (Southampton) Limited | Arts & recreation | 2015 |
| Rasco Solutions Limited | Professional & scientific | 2013 |
| Rasha Medical Limited | Health & social care | 2025 |
| Rasooli Cars Ltd | Administrative & support | 2021 |
| Ratesdata Limited | Information & communication | 2013 |
| Rathi Ltd | Wholesale & retail | 2021 |
| Rathore Limited | Professional & scientific | 2018 |
| Rathy Retail Ltd | Wholesale & retail | 2025 |
| Ravasi Ltd | Wholesale & retail | 2022 |
| Ravasi Properties Limited | Real estate | 2023 |
| Ravenscar Logistics Ltd | Transport & logistics | 2014 |
| Ravenscroft Enterprises Limited | Wholesale & retail | 2016 |
| RAW Accounting Solutions Limited | Professional & scientific | 2019 |
| RAW Capital Partners UK Limited | Administrative & support | 2023 |
| RAW Eden Beauty Limited | Other services | 2025 |
| RAY of Light Limited | Administrative & support | 2013 |
| RAY Patricio Limited | Transport & logistics | 2025 |
| Raya Barber Limited | Other services | 2024 |
| Rayah LLP | | 2024 |
| Rayamajhi Dental Therapy Services Ltd | Health & social care | 2026 |
| Rayan Enterprises Ltd | Wholesale & retail | 2020 |
| Rayan Food Centre Limited | Wholesale & retail | 2020 |
| Raye Property Investment Ltd | Real estate | 2025 |
| Rayg Limited | Construction | 2024 |
| Raymond and Broom Ltd | Real estate | 2025 |
| Raymond Arnold Limited | Professional & scientific | 2007 |
| Rays of Hope | Education | 2013 |
| Rays Technical Freelance Management Limited | Arts & recreation | 2008 |
| Rayson Viswas Services Ltd | Hospitality | 2022 |
| Rayvn Critical Event Management Limited | Information & communication | 2023 |
| Rayyan Commerce Ltd | Wholesale & retail | 2026 |
| RAZ Heating Ltd | Construction | 2020 |
| Raznet Marketing Ltd | Manufacturing | 2024 |
| Razor Barber Southampton Ltd | Other services | 2019 |
| Razor Blade Group Ltd | Information & communication | 2022 |
| Razorsouthampton Ltd | Other services | 2020 |
| Razvan GC Ltd | Transport & logistics | 2009 |
| RB Consultants Ltd | Professional & scientific | 2015 |
| RB Events & Promotions Limited | Arts & recreation | 2003 |
| RB Programmes Limited | Information & communication | 2013 |
| RBK Systems Ltd | Information & communication | 2010 |
| RBM Group (Holdings) Ltd | Wholesale & retail | 1978 |
| RBT Property Limited | Real estate | 2017 |
| RC Piping Ltd | Construction | 2013 |
| RC Traffic Management Services Limited | Construction | 2020 |
| RCB Developments Ltd | Construction | 2020 |
| RCB Management (Southern) Limited | Financial services | 2016 |
| RCB Management Limited | Financial services | 2013 |
| RCD Consult Ltd | Information & communication | 2025 |
| RCF Cleaning Services Limited | Administrative & support | 2020 |
| RCF Events & Catering Limited | Hospitality | 2025 |
| RCF Property Management Ltd | Real estate | 2020 |
| RCF Property Services Limited | Real estate | 2017 |
| RCK Group Limited | Professional & scientific | 2018 |
| Rckts FP Ltd | Financial services | 2025 |
| RCP Technologies Ltd | Information & communication | 2025 |
| RCS Transport Limited | Transport & logistics | 2002 |
| RCW Estates Ltd. | Hospitality | 2025 |
| RD Tours Ltd | Administrative & support | 2025 |
| RDC Services (UK) Ltd | Administrative & support | 2009 |
| Rdc's Courier Limited | Transport & logistics | 2025 |
| RDG Ceramics Ltd | Construction | 2023 |
| Rdotz Ltd | Information & communication | 2026 |
| RDT Management Limited | Administrative & support | 2018 |
| RE Marina Fish Bar Limited | Hospitality | 2024 |
| Re-Let Homes Ltd | Real estate | 2020 |
| RE4LISE Ltd | Professional & scientific | 2022 |
| Re:Surface ASR Limited | Construction | 2025 |
| Reach Cooperative Trust | Education | 2019 |
| Reach for the Stars (Fleet) Limited | Hospitality | 2005 |
| Reach International Holding Limited | Real estate | 2017 |
| Reach Mechanical Services Ltd | Professional & scientific | 2024 |
| Reach Social Enterprises Ltd | Health & social care | 2022 |
| React Electrical Contractors Limited | Construction | 2025 |
| Read Brothers Engineering Ltd | Manufacturing | 2021 |
| Read Electrical Services Limited | Construction | 2004 |
| Reader Fabrication Limited | Manufacturing | 2017 |
| Readstart Ltd | Manufacturing | 2023 |
| Ready Fore Golf Ltd | Information & communication | 2023 |