| Aspect Bathrooms and Heating Ltd | Construction | 2019 |
| Aspect Home Improvements and Property Maintenance Ltd | Construction | 2018 |
| Aspect Marine & Industrial Ltd | Wholesale & retail | 2019 |
| Aspins Bakery Limited | Manufacturing | 2008 |
| Asset Base South Tyneside Community Interest Company | Other services | 2006 |
| Atex Inspections Limited | Manufacturing | 2003 |
| ATU Investments Ltd. | Financial services | 2022 |
| ATU Properties Ltd | Real estate | 2025 |
| Audiocube Limited | Information & communication | 2016 |
| Aura by S&A Ltd | Manufacturing | 2025 |
| Autismable CIC | Education | 2015 |
| Autopoietic Telemetric Solutions Limited | Manufacturing | 2010 |
| Avne Limited | Administrative & support | 2023 |
| AVO Coating Inspection Ltd | Professional & scientific | 2017 |
| AVO4000 Ltd | Administrative & support | 2016 |
| AWB Security Limited | Administrative & support | 2024 |
| Axis Engineering Design Ltd | Professional & scientific | 2025 |
| Ayra Trading Ltd | Wholesale & retail | 2023 |
| Ayton Property and Management Ltd | Real estate | 2026 |
| B R Glazing NE Ltd | Construction | 2023 |
| B Swift Couriers Ltd | Transport & logistics | 2019 |
| B&C (NE) Limited | Wholesale & retail | 2017 |
| B&E FAB Ltd | Manufacturing | 2025 |
| B&S Global Retail Ltd | Wholesale & retail | 2024 |
| B&S Retail Services Ltd | Wholesale & retail | 2025 |
| B-Reflective Ltd | Wholesale & retail | 2021 |
| B.A.F. Wind Ltd. | Professional & scientific | 2023 |
| B70COL Ltd | Manufacturing | 2019 |
| Baby I Love YOU Limited | Health & social care | 2015 |
| Bains Cleaning Ltd | Administrative & support | 2025 |
| Baldr Studio Ltd. | Professional & scientific | 2020 |
| Bamburgh Property Development Limited | Real estate | 2021 |
| BAMCO77 Limited | Real estate | 2020 |
| Bangla Spice (South Shields) Ltd | Hospitality | 2015 |
| Barber and Heron Limited | | 1947 |
| Barberelle (2003) Ltd | Other services | 2003 |
| Bargain Fancy Goods Ltd | Wholesale & retail | 2026 |
| Bargain Vapers Ltd | Wholesale & retail | 2015 |
| Barley Croft Estate Management Limited | Real estate | 2019 |
| Barry Nunn Aggregates Limited | Wholesale & retail | 2020 |
| Battle Ready Performance and Training Centre CIC | Arts & recreation | 2019 |
| BDB Pine Ltd | Hospitality | 2024 |
| BDM Consult Limited | Professional & scientific | 2022 |
| BDS Building & Joinery NE Ltd | Construction | 2012 |
| BE (UK) Limited | Administrative & support | 2003 |
| Beacon System Integrity Consultants Limited | Professional & scientific | 2018 |
| Beam & Gleam Cleaning Services Limited | Other services | 2023 |
| Beamback Ltd | Information & communication | 2018 |
| Bear ASS Cheek Ltd. | Wholesale & retail | 2017 |
| Beaver Broadband Limited | Information & communication | 2021 |
| Beaver Loft Conversions Limited | Construction | 2023 |
| Beaver Media Limited | Information & communication | 2015 |
| Beehive Southshields Ltd | Hospitality | 2025 |
| Beil Properties Ltd | Real estate | 2025 |
| Believe to Run Ltd | Arts & recreation | 2022 |
| Bell Mechanical Limited | Manufacturing | 2026 |
| Bell-Cvo Limited | Households | 2023 |
| BEN Symington Fabrications Ltd | Manufacturing | 2015 |
| BEN Walker Projects Limited | Professional & scientific | 2012 |
| Benard General Building Ltd | Construction | 2023 |
| Benton Sports Academy Ltd | Arts & recreation | 2024 |
| Bents Foods Limited | Hospitality | 2020 |
| Best Floors Limited | Construction | 2002 |
| Betta Bathrooms Ltd | Construction | 2025 |
| Beyond Heat Ltd | Construction | 2021 |
| BFM Stores Ltd | Wholesale & retail | 2026 |
| Bgpg Taverns Limited | Hospitality | 2026 |
| Biddick Chippy Ltd | Hospitality | 2025 |
| Biddick Liquor Store Ltd | Wholesale & retail | 2023 |
| Big BOY Desserts Limited | Hospitality | 2023 |
| Big Fish North Chippy Ltd | Hospitality | 2026 |
| BIN Boutique Newcastle Limited | Administrative & support | 2019 |
| Birch and INK Ltd | Wholesale & retail | 2023 |
| Bishop Cuthbert 11 Management Company Limited | Real estate | 2007 |
| Bishop Cuthbert Area 6C Management Limited | Real estate | 2005 |
| BK Motor Repairs Limited | Wholesale & retail | 2026 |
| Black Dog Developments (Redcar) Limited | Real estate | 2004 |
| Black Tulip Developments Limited | Other services | 1993 |
| Blacktie Hospitality Ltd | Administrative & support | 2019 |
| Blank Ltd | Professional & scientific | 2017 |
| Blazed Limited | Manufacturing | 2017 |
| Blkengineeringdesign Limited | Professional & scientific | 2019 |
| BLM North East Ltd | Hospitality | 2024 |
| Blossom Tree Hire Co Ltd | Other services | 2018 |
| BLT Transport Ltd | Extraterritorial | 2022 |
| BLU Social Ltd | Hospitality | 2025 |
| Bluegrassdesign Limited | Manufacturing | 2015 |
| BML Property Solutions Ltd | Real estate | 2025 |
| Boardwalk Holdings Ltd | Professional & scientific | 2020 |
| Bolam Premier Sportswear Limited | Wholesale & retail | 2013 |
| Boldon Lane MOT Ltd | Wholesale & retail | 2018 |
| Boldon Lane Nails Spa Ltd | Other services | 2026 |
| Boldon Technical Ltd | Information & communication | 2019 |
| Bollard Load Test Ltd | Professional & scientific | 2022 |
| Bombay Babu Restaurants Limited | Wholesale & retail | 2024 |
| Bon-Bon-Avenue Ltd | Other services | 2024 |
| Borthwick Industries Ltd | Health & social care | 2013 |
| Boxer Property Management Limited | Real estate | 2025 |
| Boyle YER Stotts Productions Limited | Arts & recreation | 2018 |
| Brand Installations NE Ltd | Manufacturing | 2018 |