| Drum the Bass Limited | Information & communication | 2003 |
| DSM Domestic Appliance Repairs Ltd | Other services | 2025 |
| DT Newco 1 Limited | Professional & scientific | 2020 |
| DUA Beauty Salon Ltd | Other services | 2026 |
| Dudley Taylor Pharmacies Limited | Wholesale & retail | 2001 |
| Dulwich Building Co Ltd | Construction | 2024 |
| Duora Group Ltd | Real estate | 2026 |
| Duran Logistics Ltd | Transport & logistics | 2025 |
| Durva Healthcare Ltd | Health & social care | 2021 |
| Dutch and Brit Ltd | Other services | 2018 |
| Dutch Fish Ltd | Hospitality | 2025 |
| Duvall Sawyers Limited | Real estate | 2023 |
| DV Plumbing Ltd | Construction | 2022 |
| DW Carpentry and Construction Limited | Construction | 2009 |
| DWZ Properties Ltd | Real estate | 2017 |
| DY UK Transport Ltd | Transport & logistics | 2019 |
| Dygora Ltd | Arts & recreation | 2025 |
| Dymon Designs Limited | Other services | 2017 |
| DYN Construction Ltd | Construction | 2025 |
| E & E Systems Ltd | Construction | 2023 |
| E R London Couriers Ltd | Transport & logistics | 2020 |
| E&B Kebab Limited | Hospitality | 2025 |
| E&C Salon Ltd | Other services | 2025 |
| E&E Bros Catering Limited | Hospitality | 2024 |
| E&G Health & Tourism Ltd | Professional & scientific | 2021 |
| E&G Healthcare Limited | Health & social care | 2024 |
| E-Max Nutrition Ltd | Manufacturing | 2020 |
| E-Pharm Limited | Manufacturing | 1999 |
| E9/677 Limited | Financial services | 2012 |
| Eagle France Limited | Professional & scientific | 2002 |
| Eagle Groundwork and Utilities Limited | Construction | 2025 |
| Eagles United CIC | Education | 2025 |
| EAI Mechanical Services Ltd | Professional & scientific | 2021 |
| EAK Estate & Properties Ltd | Real estate | 2026 |
| Eaka Properties Ltd | Real estate | 2025 |
| Eales Enterprises Ltd | Professional & scientific | 2025 |
| Eanb Limited | Wholesale & retail | 2014 |
| Earl Grade Ltd | Information & communication | 2018 |
| Earth Electrical Concepts Ltd | Construction | 2025 |
| Earth Strong Limited | Other services | 2018 |
| East Devon Beach Property Ltd | Real estate | 2021 |
| Eastwind Logistics (UK) Ltd | Transport & logistics | 2023 |
| Eatscape Indian Ltd | Hospitality | 2025 |
| Eatwell Catering (Morden) Limited | Hospitality | 2019 |
| Echt Concept Limited | Information & communication | 2020 |
| Eclectic Gourmet Ltd | Manufacturing | 2025 |
| Eclipse Consultancy Services Limited | Administrative & support | 2007 |
| ECN 3DMEP Solutions Limited | Professional & scientific | 2013 |
| Eco Origin Limited | Wholesale & retail | 2022 |
| Eco Property Services Ltd | Administrative & support | 2024 |
| Ecom Beast Ltd | Professional & scientific | 2022 |
| Ecom Marija Limited | Wholesale & retail | 2025 |
| Ecotech Auto Services Limited | Manufacturing | 2016 |
| Ecron Ltd | Extraterritorial | 2014 |
| ED Decorating & Construction Limited | Construction | 2021 |
| ED Electrical Services Ltd | Manufacturing | 2024 |
| Edadvance Ltd | Education | 2018 |
| Edna Cods Health Care Limited | Health & social care | 2023 |
| Edtet Limited | Health & social care | 2022 |
| Educo Consulting Ltd | Education | 2023 |
| EDW Construction Ltd | Construction | 2019 |
| Edward Oaks Ltd | Real estate | 2024 |
| Edwards EFS Ltd | Administrative & support | 2019 |
| Edwin Mcginn Electrical Limited | Construction | 2008 |
| Efficiency Plus Limited | Construction | 2014 |
| Eflproductions Ltd | Extraterritorial | 2025 |
| EFS & Property Developments Ltd | Real estate | 2025 |
| EFS Property Investment Ltd | Real estate | 2025 |
| EFW Beauty Limited | Other services | 2021 |
| EGE Bookkeeping Ltd | Professional & scientific | 2020 |
| Eggo Ltd | Other services | 2022 |
| EGO Quality Consultancy Limited | Professional & scientific | 2020 |
| EHA Accountants Ltd | Professional & scientific | 2016 |
| Ehaan Ltd | Construction | 2021 |
| EHH Consultancy Limited | Construction | 2013 |
| EIS Solutions Ltd | Administrative & support | 2024 |
| EJ Design Ltd | Professional & scientific | 2018 |
| EJ Homes Development Ltd | Real estate | 2025 |
| EK Construction Limited | Construction | 2018 |
| EK Dermatology & Hair Clinics Limited | Health & social care | 2025 |
| EKN Property Investment Limited | Real estate | 2021 |
| Ekul Services Ltd | Construction | 2004 |
| ELA Caterers Limited | Hospitality | 2012 |
| ELA DRY Cleaners Limited | Other services | 2020 |
| ELA Homes Ltd | Real estate | 2024 |
| Elate Consulting Ltd | Professional & scientific | 2020 |
| Elder Place Management Company Limited | Households | 2012 |
| Eldhya Build & Developments Ltd | Real estate | 2025 |
| Electric Cars London Limited | Extraterritorial | 2021 |
| Electrotech Construction Ltd | Construction | 2025 |
| Elena Ltd | Health & social care | 2022 |
| Elevate Fitters Ltd | Construction | 2020 |
| Elevated Real Estate Investments Limited | Real estate | 2023 |
| Eleven Normanton Limited | Households | 2017 |
| Eleven Ventures Limited | Wholesale & retail | 2025 |
| Elincom Ltd | Construction | 2013 |
| Elis Services Limited | Extraterritorial | 2019 |
| Elite Painting & Finishing Ltd | Construction | 2026 |
| Elite Property (Southern) Ltd | Construction | 2021 |
| Elite Property Maintenance Group Ltd | Construction | 2021 |