| Csplatinumvapes Limited | Wholesale & retail | 2019 |
| CT Infotech Ltd | Information & communication | 2016 |
| CTK Housing Services Limited | Hospitality | 2026 |
| Cube Estate Management Limited | Administrative & support | 2026 |
| Culina Bistro Ltd | Hospitality | 2022 |
| Curiousminds Montessori Ltd | Education | 2022 |
| CUS1 Prop Ltd | Real estate | 2025 |
| Cute Suga Limited | Wholesale & retail | 2022 |
| CV Shed Ltd | Other services | 2023 |
| Cy-Group Ltd | Extraterritorial | 2017 |
| Cyber Shield Consultancy and Services Ltd | Information & communication | 2025 |
| CYE & Co Consultants Ltd | Education | 2025 |
| Cylock Limited | Professional & scientific | 2001 |
| Cyma Solutions Ltd | Professional & scientific | 2019 |
| Cynthia Levina Ltd | Real estate | 2025 |
| Cyprus American Hospital Limited | Extraterritorial | 2013 |
| Cyprus Aviation Academy Limited | Extraterritorial | 2014 |
| Cyprus Halloumi & Cheese Limited | Extraterritorial | 2008 |
| Cyprus International Airlines Limited | Extraterritorial | 2014 |
| Cyprus Turkish Airways Limited | Transport & logistics | 2014 |
| Cyrista Limited | Information & communication | 2025 |
| Czse Limited | Hospitality | 2022 |
| D & CD Properties Ltd | Construction | 2021 |
| D B Powell and Associates Limited | Administrative & support | 2011 |
| D L Jones CPS Ltd | Construction | 2018 |
| D&D Property Repairs Ltd | Financial services | 2025 |
| D&K Mortgages Ltd | Financial services | 2022 |
| D&K Perfect Clean Limited | Administrative & support | 2017 |
| D'Cruze Gardens Ltd | Administrative & support | 2025 |
| D.C.N Fire Ltd | Construction | 2026 |
| Daffodils Care and Support Services Ltd | Health & social care | 2020 |
| DAG Trading & Investments Ltd | Financial services | 2016 |
| DAIGORO789 Limited | Information & communication | 2018 |
| Daily Tropical Limited | Information & communication | 2025 |
| Dainty Darlings Childrenswear Limited | Wholesale & retail | 2016 |
| Daisy Asaf Ltd | Information & communication | 2025 |
| Daltax Ltd | Transport & logistics | 2019 |
| Damp DRS (UK) Ltd. | Construction | 2013 |
| Dancers Unite Ltd | Hospitality | 2025 |
| Dans Gardening and Maintenance Ltd | Households | 2022 |
| Dariba Design Limited | Professional & scientific | 2005 |
| Dark Pictures Limited | Information & communication | 2011 |
| Darlings Beauty Limited | Other services | 2024 |
| Darlnik Estate Limited | Real estate | 2019 |
| Daron Pearce Associates Limited | Professional & scientific | 2021 |
| Data Turbine Ltd | Information & communication | 2015 |
| Data Web Security Ltd | Information & communication | 2010 |
| Databoard Limited | Information & communication | 2008 |
| Dataera Ltd | Information & communication | 2013 |
| Datorum Limited | Professional & scientific | 2020 |
| Datta Sahaj Yoga Mission (UK) Limited | Professional & scientific | 2006 |
| Daunt Roofing Services Ltd | Construction | 2026 |
| David Akuffo Limited | Administrative & support | 2015 |
| David Care Limited | Health & social care | 2018 |
| David Symes Limited | Professional & scientific | 2013 |
| David's Christian Church Int'L Ltd | Other services | 2022 |
| Davies Consulting & Management Limited | Other services | 2013 |
| Dawini Limited | Wholesale & retail | 2011 |
| Day and Night Removal Ltd | Transport & logistics | 2017 |
| DB1 Developers Ltd | Construction | 2023 |
| DB2020 Ltd | Real estate | 2020 |
| DCN Tech Serv Ltd | Construction | 2024 |
| DE Montfort Art Ltd | Arts & recreation | 2018 |
| DE Montfort Limited | Information & communication | 2009 |
| Deafnet Limited | Information & communication | 2021 |
| Deborah and Habakkuk Direct Fresh Fruits and Vegetabled Importers Limited | Wholesale & retail | 2020 |
| Decent Property Ltd | Construction | 2018 |
| Deejays Investments Limited | Real estate | 2007 |
| Deen Digital Ltd | Information & communication | 2026 |
| Deep Blue C Limited | Arts & recreation | 2007 |
| Dees Caps UK Ltd | Wholesale & retail | 2026 |
| Deevak IT Ltd | Information & communication | 2013 |
| Dekscare Company Limited | Health & social care | 2015 |
| DEL4U Ltd | Transport & logistics | 2022 |
| Delilah's Dagger Ltd | Other services | 2014 |
| Demarc Enterprises Limited | Construction | 2002 |
| Demetris Property Ltd | Real estate | 2026 |
| Demms Advisory Limited | Professional & scientific | 2021 |
| Denia Investments Ltd | Real estate | 2024 |
| Dermethics Ltd. | Health & social care | 2020 |
| Derodra Assets Ltd | Real estate | 2017 |
| Derodra Estates Limited | Real estate | 2025 |
| DES Franklin Limited | Professional & scientific | 2025 |
| DES Voeux Consultancy Ltd | Extraterritorial | 2023 |
| Deshpande Consultants Limited | Real estate | 2012 |
| Designapex Limited | Construction | 1994 |
| Designswarm Industries Limited | Information & communication | 2010 |
| Devcap Advisers Limited | Professional & scientific | 2021 |
| Developmental Health Ltd | Health & social care | 2024 |
| Devon Road Financial Services Ltd | Professional & scientific | 2014 |
| Devotion Trading Limited | Education | 2004 |
| Devs Solutions Limited | Information & communication | 2019 |
| Devsiva Engineering Services Limited | Professional & scientific | 2026 |
| DF Groundworks&Landscaping Ltd | Construction | 2026 |
| Dfww Limited | Information & communication | 2011 |
| Dhaskeya Properties Limited | Real estate | 2026 |
| Diamond Mens Barbers Ltd | Other services | 2023 |
| Diamond Patents Ltd | Professional & scientific | 2024 |
| Digikev Ltd | Information & communication | 2025 |
| Diginet Solutions Ltd | Construction | 2022 |