| Universal Networkings Limited | Information & communication | 2016 |
| Unlocking Potential Foundation CIC | Education | 2015 |
| Unloq Solutions Ltd | Information & communication | 2024 |
| Unmole Investments Ltd | Real estate | 2024 |
| UNO Marketing Ltd | Professional & scientific | 2023 |
| Unwanted Cars and Vans Limited | Wholesale & retail | 2020 |
| Unwanted Tattoos Limited | Health & social care | 2014 |
| UP Dental Holdings Ltd | Financial services | 2024 |
| UP the Junction Limited | Hospitality | 2017 |
| Upcurve Limited | Professional & scientific | 2014 |
| Upergy Limited | Manufacturing | 1986 |
| Upgrade Property and Grounds Maintenance Ltd | Administrative & support | 2026 |
| Upkind CIC | Information & communication | 2026 |
| Uppal Investments Limited | Real estate | 2024 |
| Upton Meadows Ltd | Hospitality | 2022 |
| Upvc Distributors Limited | Extraterritorial | 1988 |
| Upwise.Ai Limited | Information & communication | 2024 |
| UR Pet P.A Services Ltd | Other services | 2010 |
| UR Wedding BF Ltd | Information & communication | 2026 |
| Urban Audio Productions Ltd | Arts & recreation | 2006 |
| Urban Bathrooms Ltd | Construction | 2022 |
| Urban Body Aesthetics Ltd | Health & social care | 2013 |
| Urban Body Ltd | Health & social care | 2010 |
| Urban Edge Developers Limited | Construction | 2007 |
| Urban Made Ltd | Real estate | 2021 |
| Urban Nest Interiors Ltd | Construction | 2025 |
| Urban Orchid Limited | Real estate | 2019 |
| Urban Pubs & Bars 2 Limited | Hospitality | 2018 |
| Urban Stone Property Ltd | Construction | 2021 |
| Urban Stone Property Solutions Limited | Construction | 2015 |
| Urban Thompson Limited | Other services | 2013 |
| Urban UK Property Investment Ltd | Real estate | 2024 |
| Urosurg Limited | Health & social care | 2008 |
| US Consultants Limited | Professional & scientific | 2022 |
| USA Summer Camp Limited | Administrative & support | 2007 |
| Usama Ameer Ltd | Wholesale & retail | 2026 |
| Uscs Acquisitions Limited | Transport & logistics | 2024 |
| Useful Digital Ltd | Information & communication | 2011 |
| USF Consulting Limited | Information & communication | 2023 |
| Usmr Homes Limited | Real estate | 2024 |
| Ussz Enterprises Ltd | Real estate | 2023 |
| UT (UK) Limited | Professional & scientific | 2005 |
| UT Property Holdings Limited | Construction | 2018 |
| Utilising Consulting Ltd | Information & communication | 2022 |
| Utility Performance Consultants Limited | Other services | 2001 |
| Utopia Designs Limited | Construction | 1993 |
| Utter Interiors Limited | Manufacturing | 2011 |
| UUA Capital Ltd | Financial services | 2017 |
| UUR Property Ltd | Real estate | 2025 |
| Uvem Ltd | Manufacturing | 2002 |
| UXD Trading Ltd | Wholesale & retail | 2018 |
| Uxton Ltd | Other services | 2007 |
| V & S Group Limited | Financial services | 2021 |
| V Care Private Limited | Health & social care | 2022 |
| V Retail Limited | Wholesale & retail | 2019 |
| V&G Oldco Limited | Manufacturing | 1937 |
| V&I Properties Limited | Real estate | 2020 |
| V12 Finance Group Limited | Financial services | 2011 |
| V12 Personal Finance Limited | Financial services | 2005 |
| V12 Retail Finance Limited | Financial services | 2002 |
| V93 Properties Limited | Real estate | 2022 |
| Vader Properties Limited | Real estate | 2019 |
| VAF Aesthetics Ltd | Health & social care | 2023 |
| Vaghela & Co. (Services) Limited | Professional & scientific | 2002 |
| Valcinante Development Limited | Construction | 2006 |
| Vale Housing Ltd | Real estate | 2025 |
| Valencia Midland Limited | Real estate | 2023 |
| Valentine Farm Limited | Agriculture & fishing | 2014 |
| Valentines Plastering Services Ltd | Construction | 2021 |
| Valley Motor Group Ltd | Wholesale & retail | 2024 |
| Valley Wholesale Carpets (2004) Limited | Financial services | 2004 |
| Valley Wholesale Carpets Limited | Wholesale & retail | 1982 |
| Vallis Homes Ltd | Real estate | 2017 |
| Valping Health Care Limited | Health & social care | 2012 |
| Valtren Distribution Ltd | Wholesale & retail | 2025 |
| Valuingyou Limited | Professional & scientific | 2014 |
| Van Isle Limited | Real estate | 2018 |
| Van Kings Ltd | Wholesale & retail | 2022 |
| Vanables Limited | Administrative & support | 2024 |
| Vanite Clinic Limited | Health & social care | 2018 |
| Vanstead Limited | Transport & logistics | 1976 |
| Vantage & Co Group Limited | Construction | 2015 |
| Vapor Cove Ltd | Wholesale & retail | 2026 |
| Vapour Services Ltd | Administrative & support | 2021 |
| Vapourmist Ltd | Wholesale & retail | 2023 |
| Variable Message Signs Limited | Manufacturing | 2014 |
| Vascusphere Limited | Health & social care | 2026 |
| Vasuki Amara Ltd | Wholesale & retail | 2024 |
| Vathi Ltd | Professional & scientific | 2013 |
| Vaughtons Holdings Limited | Financial services | 2023 |
| Vaultbridge Technology Ltd | Information & communication | 2026 |
| VC & HC Properties Limited | Households | 2018 |
| VCK Ltd | Professional & scientific | 2022 |
| VCP Associates Ltd | Health & social care | 2023 |
| Vcpulse.Io Ltd | Professional & scientific | 2023 |
| Vebabox UK Ltd | Wholesale & retail | 2024 |
| Veela Limited | Professional & scientific | 2011 |
| Veelatech Limited | Professional & scientific | 2011 |
| VEG Roti Market Ltd | Hospitality | 2025 |
| Vegasparisuk Ltd | Administrative & support | 2025 |