| Surgical Exams Limited | Education | 2023 |
| Surgical Revolutions Ltd | Health & social care | 2019 |
| Suri Marketing Ltd | Professional & scientific | 2023 |
| Surveyiq Ltd | Professional & scientific | 2025 |
| Surya Group Limited | Real estate | 2007 |
| Susan Ford Recruitment Limited | Administrative & support | 2012 |
| Sushi Midlands Limited | Hospitality | 2026 |
| Sustain Group Ltd | Construction | 2019 |
| Sustain Recruitment Limited | Administrative & support | 2011 |
| Sustainability Eco Ltd | Professional & scientific | 2010 |
| Sustainable Jade Homes Limited | Construction | 2015 |
| Sustainable Operational Solutions Ltd | Professional & scientific | 2006 |
| Sustainable Success Publications Limited | Education | 2011 |
| Sustainable Vehicle Solutions Limited | Administrative & support | 2015 |
| Suter Limited | Information & communication | 2017 |
| Sutton Lodge Management Company Limited | Households | 1982 |
| Suzanne Murphy Public Relations Ltd | Professional & scientific | 2015 |
| Suzie's Serene Dream Sea Views Limited | Hospitality | 2026 |
| SV 7 Ltd | Real estate | 2022 |
| SV Elite Homes Limited | Real estate | 2025 |
| Svasti Global Solutions Ltd | Professional & scientific | 2025 |
| Svbvs Limited | Real estate | 2017 |
| SVO Estates Ltd | Real estate | 2020 |
| SVP Health Limited | Health & social care | 2024 |
| SW Opex Limited | Professional & scientific | 2025 |
| SW77 Limited | Professional & scientific | 2022 |
| Swallowfield Equestrian Limited | Arts & recreation | 1995 |
| Swan Surveyors Limited | Real estate | 2011 |
| Swani Alliances Limited | Real estate | 2025 |
| Swann Technology Limited | Transport & logistics | 1985 |
| Swans View Management Company Limited | Households | 2004 |
| Swansea-Light Ltd | Real estate | 2023 |
| Swaraaj Ltd | Information & communication | 2021 |
| Sway Solutions Limited | Professional & scientific | 2015 |
| Sweeney's Alloys Ltd | Manufacturing | 2022 |
| Swift Buy Online Ltd | Wholesale & retail | 2026 |
| Swift Circle Ltd | Real estate | 2020 |
| Swift FIX 24/7 Ltd | Administrative & support | 2025 |
| Swift Flooring and Prep Solutions Ltd | Construction | 2018 |
| Swift Flooring Ltd | Construction | 2023 |
| Swift FM Solutions Ltd | Administrative & support | 2025 |
| Swift Move Removals Ltd | Transport & logistics | 2025 |
| Swift N Simple Solutions Ltd | Information & communication | 2014 |
| Swiftlet Properties Ltd | Real estate | 2019 |
| Swiftpath Solutions Limited | Health & social care | 2025 |
| Swig Club Ltd | Professional & scientific | 2021 |
| Swigable Limited | Wholesale & retail | 2025 |
| Swim QED Ltd | Education | 2017 |
| Swim Schbang Limited | Wholesale & retail | 2024 |
| Swimswims Limited | Wholesale & retail | 2018 |
| Swingsimz Limited | Information & communication | 2025 |
| Swipe Studios Interactive Limited | Information & communication | 2017 |
| Swish Building Products Limited | Extraterritorial | 1994 |
| Swiss Homes Limited | Real estate | 2021 |
| Switch Space Solihull Limited | Real estate | 2026 |
| SWL Customer Analytics Ltd | Information & communication | 2024 |
| SWL Group Holdings Limited | Financial services | 2021 |
| SWL Group Ltd | Professional & scientific | 2006 |
| Swopodoms Ltd | Wholesale & retail | 2022 |
| Swopsee Ltd | Information & communication | 2025 |
| Sword Homes Ltd | Real estate | 2026 |
| Swuk Trading Ltd | Wholesale & retail | 2022 |
| SY Investments Limited | Real estate | 2014 |
| SYC2J Banbury Ltd | Wholesale & retail | 2022 |
| SYC2J Coventry Limited | Wholesale & retail | 2026 |
| SYC2J Redditch Ltd | Wholesale & retail | 2022 |
| SYC2J Stratford Ltd | Wholesale & retail | 2022 |
| SYC2J Sutton Coldfield Ltd | Wholesale & retail | 2024 |
| SYC2J Tamworth Ltd | Wholesale & retail | 2022 |
| SYC2J Touchwood Solihull Ltd | Wholesale & retail | 2023 |
| SYC2J Wolverhampton Ltd | Wholesale & retail | 2023 |
| Sycamore Gardens Management Company Solihull Limited | Households | 2020 |
| Sydney Mitchell Estate Agents Limited | Professional & scientific | 2007 |
| Sydney Mitchell LLP | | 2009 |
| Sydney Mitchell Services Limited | Professional & scientific | 1994 |
| Symphony Court Management Limited | Households | 1995 |
| Synai Limited | Professional & scientific | 2025 |
| Synergy Body & Spine Clinic Ltd | Health & social care | 2025 |
| Synergy Film Studios Ltd | Professional & scientific | 2022 |
| Synergy Group HB Ltd | Real estate | 2023 |
| Synergy Maintenance Limited | Administrative & support | 2019 |
| Synergy Premises Limited | Real estate | 2017 |
| Synergy Serve Ltd | Professional & scientific | 2022 |
| Syntaxis Consulting Limited | Information & communication | 2013 |
| Synvestment Holdings Limited | Hospitality | 2021 |
| Sysanalyst Limited | Information & communication | 2007 |
| Syseco for Accounting Services Ltd | Professional & scientific | 2021 |
| Systemedge Strategy Ltd | Professional & scientific | 2025 |
| Systems Delivery Limited | Professional & scientific | 2009 |
| Systems Inc UK Ltd | Information & communication | 2007 |
| Systems Target Solutions Ltd | Professional & scientific | 2025 |
| Systems Union Group Limited | Financial services | 1992 |
| SYX Kitchens Limited | Wholesale & retail | 2023 |
| SZ Training Limited | Education | 2024 |
| SZH Medics Ltd | Health & social care | 2026 |
| T & J Carpets Ltd | Construction | 2017 |
| T & K Construction Ltd | Construction | 2019 |
| T & Q Foods Ltd | Wholesale & retail | 2024 |
| T & S Contracts Ltd | Construction | 2020 |
| T & S Roofing Ltd | Construction | 2013 |