| Stay for Work Limited | Administrative & support | 2023 |
| Stayline Limited | Wholesale & retail | 2016 |
| STB Leasing Limited | Financial services | 1982 |
| Steadfast Industrial Services Limited | Water & waste | 1992 |
| Steadford Ltd | Professional & scientific | 2016 |
| Steadman Property Limited | Real estate | 2025 |
| Steady Roots Ltd | Professional & scientific | 2026 |
| Steakholders Steak & Chips Ltd | Hospitality | 2026 |
| Steals and Deals Ltd | Administrative & support | 2025 |
| Steaming Sam's Cleaning & Maintenance Ltd | Administrative & support | 2015 |
| Steel Fixing Solution Ltd | Administrative & support | 2017 |
| Steele IT Solutions Limited | Information & communication | 2016 |
| Steelhouse Services Ltd | Construction | 2019 |
| Steelier Ltd | Professional & scientific | 2025 |
| Stella Brookes Ltd | Professional & scientific | 1999 |
| Stella Property Developments Limited | Real estate | 2025 |
| Stellar Aluminium Limited | Extraterritorial | 2017 |
| Stellar Building Solutions Ltd | Construction | 2023 |
| Stellar Systems Ltd | Information & communication | 2023 |
| Step Into Teaching Limited | Administrative & support | 2016 |
| Stephen Bailey Plumbing Services Ltd | Construction | 2019 |
| Stephen Delaney Associates Limited | Professional & scientific | 2003 |
| Stephen Esslemont Ltd | Extraterritorial | 2015 |
| Stephen Hartley Interior Technician Limited | Construction | 2007 |
| Sterling Accountancy (Birmingham) Limited | Professional & scientific | 2004 |
| Sterling International Products Ltd | Wholesale & retail | 2025 |
| Sterling Luxury Cars Limited | Transport & logistics | 2022 |
| Stes Industrial Limited | Wholesale & retail | 2026 |
| Steve Harris Carpentry Limited | Construction | 2025 |
| Steve Pearse Consulting Limited | Professional & scientific | 2016 |
| Steve's Industries Limited | Other services | 2002 |
| Stevebuild Limited | Construction | 2018 |
| Stevie Morrison Sailing Ltd | Administrative & support | 2015 |
| Stillby Limited | Administrative & support | 2012 |
| Stir & Serve Ltd | Hospitality | 2024 |
| Stirling Land and Planning Limited | Professional & scientific | 2022 |
| STL Project Management Limited | Professional & scientific | 2015 |
| Stlc Techno Solutions Limited | Information & communication | 2013 |
| Stobswell 1865 Limited | Real estate | 2004 |
| Stoics Medical Ltd | Health & social care | 2017 |
| Stokesley Devco LLP | | 2016 |
| Stokesley Holdco 1 LLP | | 2016 |
| Stokesley Holdco 2 LLP | | 2016 |
| Stone Village Consulting Ltd | Information & communication | 2022 |
| Stoneage Building Contractors Limited | Construction | 2017 |
| Stonebow (Drakes Broughton) Limited | Construction | 2024 |
| Stonegate Entity 2 Limited | Hospitality | 2023 |
| Stonegate Management Nominees Limited | Professional & scientific | 2020 |
| Stonegate Property (Craft) Limited | Administrative & support | 2021 |
| Stonegate Property (L&T) Limited | Administrative & support | 2021 |
| Stonegate Property Midco Limited | Administrative & support | 2021 |
| Stonegate Property Topco Limited | Administrative & support | 2021 |
| Stonegate PUB Company Financing 2019 PLC | Hospitality | 2019 |
| Stonegate PUB Company Financing Limited | Administrative & support | 2014 |
| Stonegate PUB Company Pikco Holdings Limited | Hospitality | 2019 |
| Stonegate PUB Company Pikco Limited | Hospitality | 2019 |
| Stoneglad Limited | Real estate | 2024 |
| Stoneleigh Professional Services Limited | Information & communication | 2021 |
| Stoneleigh Retirement Planning Limited | Financial services | 2016 |
| Stonor Housing Ltd | Real estate | 2025 |
| Stonor Park Estates LLP | | 2023 |
| Stonor Survey Limited | Construction | 2016 |
| Stoptide Cottage Limited | Real estate | 2019 |
| Storm IT Technology Limited | Information & communication | 2000 |
| Stormking Plastics Limited | Extraterritorial | 1983 |
| Stove Installation Supplies Ltd | Wholesale & retail | 2020 |
| Stowstays Ltd | Hospitality | 2025 |
| Straight Line Survey Services Ltd | Administrative & support | 2006 |
| Strataigem Ltd | Information & communication | 2025 |
| Strategic Investment Advice Limited | Professional & scientific | 2018 |
| Stratford Central LLP | | 2024 |
| Stratford Corporate Finance Limited | Financial services | 2007 |
| Stratford Court Estate Management Limited | Households | 2003 |
| Stratofortress Aviation Limited | Transport & logistics | 2024 |
| Stratton Real Estates Ltd | Hospitality | 2020 |
| Strava Consulting Limited | Professional & scientific | 2015 |
| Strava Developments Limited | Other services | 2022 |
| Streamline Software Limited | Information & communication | 2013 |
| Street & Alley Limited | Hospitality | 2026 |
| Street Bytez Ltd | Hospitality | 2025 |
| Streets Ahead Properties Limited | Real estate | 1998 |
| Streetsbrook Academy Trust | Education | 2016 |
| Streetsbrook Property Developments LLP | | 2018 |
| Strength Edge Tech Ltd | Manufacturing | 2025 |
| Stretton Estates Limited | Construction | 2025 |
| Stretton Homes Limited | Construction | 1999 |
| Stride Coaching Limited | Other services | 2024 |
| Stride Physiotherapy Ltd | Health & social care | 2023 |
| Strike Back Self Defence Ltd | Arts & recreation | 2024 |
| STRIKE9T CIC | Arts & recreation | 2019 |
| STRIKE9TRAINING Ltd | Arts & recreation | 2016 |
| Strive to Succeed Limited | Professional & scientific | 2018 |
| Structured Care Ltd | Health & social care | 2015 |
| Stsk Consulting Ltd | Professional & scientific | 2018 |
| Stsk Consulting Services Limited | Professional & scientific | 2026 |
| Stsk Invest Limited | Real estate | 2026 |
| Stsk Ltd | Professional & scientific | 2026 |
| STT Property Limited | Real estate | 2002 |
| STU Holdings Ltd | Real estate | 2022 |
| Stuart Charles Estate Agents Ltd | Real estate | 2021 |