| Solihull Parent Carer Voice C.I.C. | Information & communication | 2021 |
| Solihull Physiotherapy Clinic Limited | Health & social care | 2007 |
| Solihull Plant Services Ltd | Construction | 2016 |
| Solihull Plastering Contractors Limited | Construction | 1990 |
| Solihull Play Therapy and Counselling Service Limited | Administrative & support | 2015 |
| Solihull Play Town Ltd | Health & social care | 2021 |
| Solihull Plumbing & Heating Ltd | Construction | 2020 |
| Solihull Professional Tuition Centre Ltd | Education | 2026 |
| Solihull Property Company Limited | Real estate | 2013 |
| Solihull Property Solutions Limited | Construction | 2026 |
| Solihull Property Specialists Ltd | Real estate | 2025 |
| Solihull Residential Lettings Limited | Real estate | 2020 |
| Solihull Riding Club Trust Corporation Limited | Financial services | 2016 |
| Solihull Sarbojonin Limited | Other services | 2025 |
| Solihull School Enterprises Limited | Real estate | 2018 |
| Solihull Services Ltd | Professional & scientific | 2025 |
| Solihull Short Stays Limited | Real estate | 2024 |
| Solihull Sports Hub Ltd | Arts & recreation | 2026 |
| Solihull Spotlight Ltd | Information & communication | 2026 |
| Solihull Subs Ltd | Hospitality | 2015 |
| Solihull Superkings Cricket Club Ltd | Arts & recreation | 2023 |
| Solihull Supported Housing C.I.C. | Hospitality | 2020 |
| Solihull Sushi Ltd | Hospitality | 2016 |
| Solihull Sweet Shop Limited | Wholesale & retail | 2025 |
| Solihull Swimming Club Limited | Arts & recreation | 2020 |
| Solihull Taste of Asia Limited | Hospitality | 2026 |
| Solihull Taxi Cabs Ltd | Transport & logistics | 2017 |
| Solihull Technologies Ltd | Information & communication | 2025 |
| Solihull Tiling Specialists Ltd | Construction | 2019 |
| Solihull Time to Care Limited | Health & social care | 2015 |
| Solihull Wedding Creations Limited | Wholesale & retail | 2025 |
| Solihull Wheel Repair Limited | Wholesale & retail | 2023 |
| Solihull Wills Ltd | Professional & scientific | 2024 |
| Solihull Women's Stride Squad CIC | Other services | 2025 |
| Solihull's Real PCS Ltd | Health & social care | 2026 |
| Solihullhomecare Limited | Health & social care | 2013 |
| Solomons Legal LLP | | 2006 |
| Soltax Accountancy Limited | Professional & scientific | 2018 |
| Solubytes Ltd | Information & communication | 2020 |
| Solution Insight Ltd | Professional & scientific | 2010 |
| Solutions in Spades Ltd | Information & communication | 2026 |
| Solve (UK) Limited | Professional & scientific | 2001 |
| Sonal & Vikram Properties Limited | Real estate | 2025 |
| Sonali Supermarket (Birmingham) Ltd | Wholesale & retail | 2016 |
| Sonali Supermarket (Midlands) Ltd | Wholesale & retail | 2020 |
| Sonali Supermarket Oldham Limited | Wholesale & retail | 2009 |
| Sonbeam Services Limited | Real estate | 2023 |
| Sondiak and Wairumu Ltd | Wholesale & retail | 2026 |
| Sookshma Software Limited | Information & communication | 1995 |
| Sophie Louise Holdings Limited | Financial services | 2025 |
| Sophie Louise Investments Limited | Financial services | 2025 |
| Sophie Parcels Limited | Transport & logistics | 2025 |
| Sophie Solutions 2025 Limited | Administrative & support | 2025 |
| Sophie Solutions Limited | Transport & logistics | 2020 |
| Sophren Limited | Professional & scientific | 2026 |
| Sortzi Ltd | Information & communication | 2026 |
| Soru Holdings Limited | Other services | 2018 |
| Soru Jewels Limited | Other services | 2017 |
| SOS Group Services Limited | Construction | 1984 |
| Sostudents (One) Ltd | Real estate | 2018 |
| Sostudents (Three) Ltd | Real estate | 2017 |
| Sostudents (Two) Ltd | Real estate | 2017 |
| Soti Limited | Information & communication | 2013 |
| Soul Partner Holdings Limited | Other services | 2025 |
| Sound of Health Limited | Health & social care | 2003 |
| Sound Trucks Limited | Hospitality | 2024 |
| Sounder Limited | Other services | 2025 |
| Sounds Alarming Limited | Other services | 1997 |
| Soundsnap Studio Ltd | Information & communication | 2025 |
| Sour Haven Ltd | Hospitality | 2021 |
| Sour Sausage Ltd | Wholesale & retail | 2021 |
| Sourced by JB Ltd | Real estate | 2019 |
| South Bailey Development Limited | Education | 2022 |
| South Birmingham Ductwork Limited | Construction | 2019 |
| South Grove (Erdington) Limited | Real estate | 1982 |
| South Liverpool Hair and Beauty Limited | Other services | 2016 |
| South Road Dental Practice Limited | Health & social care | 2009 |
| South Staffs Mortgage Services Ltd | Financial services | 2020 |
| South View Leamington Management Limited | Real estate | 2004 |
| South West Independent Medical Services Limited | Health & social care | 1989 |
| South West Tanks Limited | Wholesale & retail | 2010 |
| Southampton Port Parking Ltd | Transport & logistics | 2025 |
| Southcotes (Leamington Spa) Management Company Limited | Households | 2005 |
| Southern Building Plastics Limited | Extraterritorial | 2023 |
| Southfork Investments Ltd | Real estate | 2017 |
| Southgate Splash Limited | Professional & scientific | 2006 |
| Southpaw Property Solutions Ltd | Households | 2020 |
| Sovereign Tree Surgeons Limited | Administrative & support | 2025 |
| SP Media 19 Limited | Information & communication | 2020 |
| SP Roofing Solutions Limited | Construction | 2022 |
| Spa CE Management Limited | Households | 2006 |
| Spa Web Design Limited | Information & communication | 2003 |
| Spare ME Parts Limited | Wholesale & retail | 2024 |
| Spark Brands Limited | Wholesale & retail | 2013 |
| Sparkhill Studios Ltd | Transport & logistics | 2017 |
| Sparkle Maintenance Limited | Administrative & support | 2023 |
| Sparkle Window Cleaning Limited | Administrative & support | 2009 |
| Sparkleey Ltd | Administrative & support | 2026 |
| Sparkling Sihra Ltd | Administrative & support | 2025 |
| Spartan Direct Limited | Wholesale & retail | 1996 |