| Dropzzy Ltd | Transport & logistics | 2025 |
| DS Motorworld Ltd | Wholesale & retail | 2025 |
| DU Coffee Limited | Hospitality | 2024 |
| DU Grill Ltd | Hospitality | 2026 |
| DUA Trades U.K. Limited | Wholesale & retail | 2024 |
| Dubb Properties Limited | Real estate | 2005 |
| Duccio Limited | Arts & recreation | 2006 |
| Dudley Fish Bar Ltd | Hospitality | 2023 |
| Dudley General Stores Ltd | Wholesale & retail | 2019 |
| Dugdale Properties Ltd | Real estate | 2024 |
| Dunnings Stores Ltd | Wholesale & retail | 2025 |
| Dvuk Clothing Ltd | Wholesale & retail | 2025 |
| Dwam Holdco Ltd | Financial services | 2026 |
| Dwphg Holdco Ltd | Financial services | 2026 |
| Dylan Group Midlands Ltd | Other services | 2024 |
| Dylans Drink Shop Ltd | Wholesale & retail | 2016 |
| Dynamic Energy Saviour Limited | Construction | 2023 |
| Dynamic Movers Ltd | Transport & logistics | 2024 |
| Dynamic Properties Solutions Ltd | Real estate | 2025 |
| Dynamic Services Midland Ltd | Transport & logistics | 2022 |
| Dynmark Ltd | Information & communication | 2019 |
| Dzcleaning Services Limited | Administrative & support | 2025 |
| Dziezormz Ltd | Health & social care | 2023 |
| DÈ Arkhurst Group Limited | Manufacturing | 2020 |
| E R Automotive Ltd | Wholesale & retail | 2019 |
| E-Siwa Enterprises Ltd | Wholesale & retail | 2020 |
| E-Student Limited | Information & communication | 2018 |
| Ea-Cre Limited | Real estate | 2023 |
| Eactuate Limited | Wholesale & retail | 2020 |
| Eagle Production Ltd | Professional & scientific | 2023 |
| Eamt Limited | Real estate | 2018 |
| Eardley Lighting Solutions Ltd | Information & communication | 2020 |
| Easybuy Online Ltd | Wholesale & retail | 2026 |
| Easybuycn Trading Limited | Wholesale & retail | 2019 |
| Easyfit Tyres 24/7 Ltd | Wholesale & retail | 2026 |
| Eazy Recycling Ltd | Manufacturing | 2018 |
| EBH Valeting Ltd | Administrative & support | 2023 |
| Ebony Organic Empire Limited | Manufacturing | 2023 |
| Eco Energy Savers Ltd | Construction | 2022 |
| Eco Heat Shop Ltd | Construction | 2025 |
| Eco Insulation Solution U.K. Ltd | Transport & logistics | 2024 |
| Eco Motion Tech Ltd | Wholesale & retail | 2020 |
| Ecogum Limited | Administrative & support | 2012 |
| Ecolife Club Ltd | Water & waste | 2025 |
| Ecomlights Ltd | Wholesale & retail | 2023 |
| Ecomotion Group Limited | Wholesale & retail | 2020 |
| Economical Investment Limited | Real estate | 1993 |
| Ecospares Ltd | Wholesale & retail | 2015 |
| Eddy Automotive Ltd | Wholesale & retail | 2025 |
| Edgbaston Capital Holdings Ltd | Financial services | 2024 |
| Edgbaston Health Limited | Health & social care | 2023 |
| Edgbaston MOT Centre Ltd | Wholesale & retail | 2016 |
| Edge Coffee Shop Ltd | Hospitality | 2025 |
| Edmontongreen Transport Ltd | Transport & logistics | 2025 |
| Education and Skills for Life Ltd | Extraterritorial | 2011 |
| Edymar Ltd | Transport & logistics | 2018 |
| Ee-Zee Life Limited | Wholesale & retail | 2021 |
| Eg&C Limited | Construction | 2023 |
| Egarage App Ltd | Information & communication | 2022 |
| Eggless Cake Shop Smethwick Limited | Wholesale & retail | 2013 |
| Egreefit Private Limited | Wholesale & retail | 2025 |
| Ehhr SPV Ltd | Real estate | 2016 |
| Ehsaan Properties Ltd | Real estate | 2020 |
| Einstein Studio Ltd | Wholesale & retail | 2026 |
| Eithad Developers Ltd | Construction | 2024 |
| EKM Building and Maintenance Ltd | Construction | 2025 |
| Ekman Logistics Ltd | Transport & logistics | 2026 |
| Elecable MAN Limited | Professional & scientific | 2016 |
| Electrolyzed AI Ltd | Health & social care | 2026 |
| Electus Global Education Company Limited | Education | 2016 |
| Elegance Home Furniture Ltd | Wholesale & retail | 2019 |
| Elegance Real Estate Ltd | Real estate | 2024 |
| Elegant Phones Limited | Wholesale & retail | 2018 |
| Elegant Property Ltd | Real estate | 2019 |
| Eletteming Corporation Ltd | Health & social care | 2020 |
| Elis Shand Ltd | Real estate | 2020 |
| Elite Destinations Travel Ltd | Transport & logistics | 2025 |
| Elite Glass Finishing Ltd | Manufacturing | 2023 |
| Elite Resources Limited | Transport & logistics | 2026 |
| Elite Services Midlands Ltd | Other services | 2020 |
| Elitekey Management Limited | Administrative & support | 2025 |
| Ella's Magical Garden Ltd | Wholesale & retail | 2022 |
| Ellahi Properties Ltd | Real estate | 2021 |
| Elmbridge Health Care Ltd | Health & social care | 2026 |
| ELY PJ Ltd | Hospitality | 2024 |
| EMA Electrical Limited | Construction | 2020 |
| Embassy Properties (BD) Ltd | Real estate | 2023 |
| Embsay Limited | Information & communication | 2019 |
| Emellyaa Limited | Hospitality | 2015 |
| Emiljan's Motor Repairs Ltd | Wholesale & retail | 2025 |
| Empire Coaching Limited | Education | 2017 |
| Empire House Care Ltd | Health & social care | 2025 |
| Empire Pizza and Fried Chicken Ltd | Hospitality | 2025 |
| Employment Contractor Group Ltd | Administrative & support | 2025 |
| Emrn Capital Limited | Real estate | 2018 |
| EMS Couriers Ltd | Transport & logistics | 2026 |
| Endeavour Education Services Ltd | Education | 2019 |
| Engineering Nation Limited | Professional & scientific | 2025 |
| Enhanced Ideas Limited | Other services | 2007 |
| Enhancify Ltd | Education | 2025 |