| Cozy Coffee (Birmingham) Ltd | Hospitality | 2026 |
| CP Therapy Ltd | Health & social care | 2024 |
| CPA System Designs Limited | Information & communication | 2024 |
| Crackle Property Limited | Real estate | 2020 |
| Crafters Vinyl Emporium Ltd | Wholesale & retail | 2021 |
| Craiova Body Repairs Limited | Manufacturing | 2017 |
| Creative Bedrooms & Kitchens UK Limited | Manufacturing | 2013 |
| Creative Decorations Limited | Wholesale & retail | 2018 |
| Creative Joinery Limited | Manufacturing | 2015 |
| Crepe Delight Ltd | Hospitality | 2025 |
| Crepella Limited | Hospitality | 2025 |
| Crescent (North & Midlands) Limited | Manufacturing | 2025 |
| Crescent Law Ltd | Professional & scientific | 2024 |
| Crestvale Ltd | Real estate | 2025 |
| Crispy Bites Smethwick Ltd | Hospitality | 2025 |
| Crossco Express Limited | Wholesale & retail | 2023 |
| Cruzaa Ltd | Wholesale & retail | 2015 |
| Crystal Repairs 42 Ltd | Administrative & support | 2022 |
| CSD IT Ltd | Construction | 2020 |
| CSD Projects Ltd | Construction | 2020 |
| CSD Tech Ltd | Construction | 2020 |
| CSG Services Ltd | Construction | 2020 |
| CST Transport Ltd | Transport & logistics | 2019 |
| Cubiz Ltd | Information & communication | 2025 |
| Cuddly Bears Little Explorers Ltd | Health & social care | 2025 |
| Curry and ALE Ltd | Hospitality | 2019 |
| Custard and Creams Ltd | Hospitality | 2024 |
| Cwmg Properties Limited | Real estate | 2022 |
| Cyber IT Limited | Construction | 2020 |
| Cyber IT Systems Ltd | Construction | 2020 |
| Cyberdata Systems Ltd | Construction | 2020 |
| Cybertrade Store Ltd | Wholesale & retail | 2021 |
| Cybex Services Ltd | Wholesale & retail | 2021 |
| D & B Drinkstop Limited | Wholesale & retail | 2015 |
| D & P Stores Ltd | Wholesale & retail | 2023 |
| D&G Property Management (Tipton) Ltd | Construction | 2023 |
| D&M (B'Ham) Ltd | Wholesale & retail | 2025 |
| D&M Extra Bargain Limited | Wholesale & retail | 2019 |
| D&M Works Ltd | Transport & logistics | 2024 |
| D. Wilson Architectural Metalwork Ltd | Manufacturing | 1993 |
| D. Wilson Property (Cannock) Ltd | Construction | 2022 |
| D. Wilson Property (Halesowen) Limited | Construction | 2022 |
| D. Wilson Property Holding Group Limited | Real estate | 2008 |
| D.S.Hayer Transport Ltd | Transport & logistics | 2020 |
| D.Wilson Holdings Limited | Financial services | 2016 |
| Dacosta Grove Entertainment Ltd | Arts & recreation | 2025 |
| Dafidi Visuals Ltd | Professional & scientific | 2026 |
| Dagm Limited | Real estate | 2025 |
| Daily Drinks 007 Limited | Wholesale & retail | 2020 |
| Dakh Holdings Ltd | Financial services | 2025 |
| Dakh Investments Ltd | Real estate | 2025 |
| Daljeet Tailor Ltd | Manufacturing | 2017 |
| Dallas Tech Ltd | Construction | 2020 |
| Dalo Cafe Ltd | Hospitality | 2021 |
| Dalya House Limited | Households | 2025 |
| Dalys Tiling Ltd | Construction | 2018 |
| Damcon Automobiles Company Limited | Wholesale & retail | 2024 |
| Damcon Estates Ltd | Real estate | 2025 |
| Damcon Software Solutions Limited | Information & communication | 2023 |
| Danesh FAR Limited | Hospitality | 2024 |
| Dani Building Ltd | Construction | 2025 |
| Danmens Ltd | Transport & logistics | 2026 |
| Danmyke Limited | Construction | 2017 |
| Danny Construction Ltd | Construction | 2018 |
| Dapobo Limited | Health & social care | 2023 |
| DAR UL Qlam Limited | Public administration | 2019 |
| Dara Property Ltd | Real estate | 2025 |
| Dardania Place Ltd | Hospitality | 2019 |
| Darius Denis Dumitru Ltd | Transport & logistics | 2025 |
| Darrenneilnelson Ltd | Extraterritorial | 2024 |
| Darrez Construction Ltd | Construction | 2025 |
| Darshan Foods Ltd | Manufacturing | 2024 |
| Dastro Services Ltd | Transport & logistics | 2021 |
| Data Works (Birmingham) Ltd | Information & communication | 2008 |
| Davek Kitchen Ltd | Hospitality | 2025 |
| Davenports Brewery CB Ltd | Extraterritorial | 2013 |
| Daventry Fish Bar Ltd | Hospitality | 2023 |
| David's Construction Ltd | Construction | 2020 |
| Day & Night Store Limited | Wholesale & retail | 2026 |
| DB General Building Services Limited | Construction | 2022 |
| DC Facilities Consultancy Limited | Administrative & support | 2026 |
| DC Stamatin Ltd | Extraterritorial | 2018 |
| DCT WM Limited | Construction | 2024 |
| DD Constructions Limited | Construction | 2022 |
| DD Midlands Ltd | Construction | 2026 |
| Decorating Masters and Cleaning Ltd | Construction | 2023 |
| Deen Connect Limited | Wholesale & retail | 2025 |
| Deephysio Limited | Other services | 2019 |
| Defect Hunters Ltd | Information & communication | 2019 |
| Deledy 2018 Ltd | Transport & logistics | 2018 |
| Delivering Care Direct Ltd | Health & social care | 2010 |
| Delivery Investigations Limited | Transport & logistics | 2005 |
| Dell Limited | Wholesale & retail | 2025 |
| Delta V Automotive Ltd | Wholesale & retail | 2026 |
| Demitasse Group Limited | Hospitality | 2019 |
| Demon WM Ltd | Construction | 2026 |
| DEN of Echoes Limited | Hospitality | 2015 |
| Dent-Pall Ltd | Health & social care | 2018 |
| Dervish-Lang Equestrian Limited | Agriculture & fishing | 2015 |
| Desi 2 Private Limited | Hospitality | 2025 |