| Unity Maintenance UK Ltd | Manufacturing | 2024 |
| Unityten Consulting Limited | Information & communication | 2017 |
| Universal Auto Master Ltd | Wholesale & retail | 2024 |
| Universal Boutique Ltd | Wholesale & retail | 2024 |
| Universal Clean Services Ltd | Administrative & support | 2026 |
| Universal Distribution Ltd | Transport & logistics | 2013 |
| Universal Locks Limited | Wholesale & retail | 1988 |
| Universal Organic Products Ltd | Hospitality | 2021 |
| Universal Research Ltd | Professional & scientific | 2018 |
| Universe E Limited | Arts & recreation | 2024 |
| Universe FAR Ltd | Manufacturing | 2024 |
| Universe IT Group Ltd | Other services | 2020 |
| Univrs Ltd | Information & communication | 2021 |
| Unknotted Ltd | Other services | 2024 |
| Unleashed Talent Management Ltd | Professional & scientific | 2021 |
| UNO Click Collections Ltd | Wholesale & retail | 2020 |
| UNO Hotels Ltd | Hospitality | 2023 |
| UNO Thames Hotel Ltd | Hospitality | 2023 |
| Unsa FM Services Limited | Administrative & support | 2024 |
| Unus London Ltd | Information & communication | 2022 |
| Unused Travel Money Limited | Financial services | 2015 |
| UP 26 Construction Limited | Construction | 2025 |
| UP BT Ltd | Other services | 2024 |
| UP UP and Away Events Limited | Wholesale & retail | 2025 |
| Upahaar Box Ltd | Wholesale & retail | 2026 |
| Uppal & Co Accountants (UK) Ltd | Professional & scientific | 2012 |
| Uppal Couriers Limited | Transport & logistics | 2008 |
| Uppal Design Ltd | Professional & scientific | 2024 |
| Uppal Freight Services Ltd | Transport & logistics | 2026 |
| Uppal Transport Ltd | Transport & logistics | 2025 |
| Upper Room Acts Ltd | Professional & scientific | 2014 |
| Upsurge Business Services Limited | Administrative & support | 2025 |
| Uptempo Limited | Construction | 2013 |
| Upton Accountants Ltd | Professional & scientific | 2026 |
| Upton Assets Ltd | Real estate | 2022 |
| Upton Care Plus Ltd | Health & social care | 2022 |
| Upton Court Accountants Ltd | Professional & scientific | 2026 |
| Upton Energy Ltd | Professional & scientific | 2005 |
| Upwant Limited | Wholesale & retail | 2025 |
| Upward & Forwards Ltd | Professional & scientific | 2016 |
| Ur-B Products Ltd | Wholesale & retail | 2025 |
| Uraudits Limited | Information & communication | 2023 |
| Urban Builders Ltd | Construction | 2024 |
| Urban CAB Ltd | Transport & logistics | 2019 |
| Urban Cart Ltd | Wholesale & retail | 2025 |
| Urban Cloud Ltd | Wholesale & retail | 2024 |
| Urban Crusader Limited | Wholesale & retail | 2018 |
| Urban Doors&Window Glazing Ltd | Construction | 2025 |
| Urban Food Street Limited | Hospitality | 2022 |
| Urban Green Chase Ltd | Wholesale & retail | 2023 |
| Urban Haven Group Ltd | Administrative & support | 2025 |
| Urban Haven Store Ltd | Wholesale & retail | 2025 |
| Urban Herb Incorporated Ltd | Wholesale & retail | 2022 |
| Urban Hive South Ltd | Real estate | 2025 |
| Urban Rose Consulting Ltd | Information & communication | 2021 |
| Urban Shelter Ltd | Real estate | 2019 |
| Urbanedge Property Developers Ltd | Construction | 2026 |
| Urbanhome Constructions Ltd | Construction | 2022 |
| Urbanhue Ltd | Wholesale & retail | 2025 |
| Urbanika Limited | Real estate | 2025 |
| Urbanlux Travel Ltd | Transport & logistics | 2026 |
| Urbannest HMO Ltd | Real estate | 2023 |
| Urbanreach Realty Ltd | Real estate | 2025 |
| Urbanstay Properties Ltd | Real estate | 2026 |
| Uread Solutions Limited | Professional & scientific | 2020 |
| Urgent Carriers Limited | Transport & logistics | 2010 |
| URO DIA MED Ltd | Health & social care | 2014 |
| URO Logic Ltd | Health & social care | 2025 |
| URS 4 Limited | Wholesale & retail | 2021 |
| Uruthi Limited | Information & communication | 2024 |
| Urwelcom Ltd | Real estate | 2024 |
| US Business Advisers Limited | Professional & scientific | 2014 |
| US Dana International Food Services Ltd | Wholesale & retail | 2025 |
| Usha Cargo International Ltd | Transport & logistics | 2026 |
| Usha Enterprises Limited | Real estate | 2017 |
| Ushmesh IT Solution Ltd | Information & communication | 2024 |
| Usman and Marrium Limited | Real estate | 2024 |
| Usman Consultancy Ltd | Administrative & support | 2021 |
| USP Property Ltd | Real estate | 2021 |
| USS Technologies Limited | Information & communication | 2018 |
| UTA Consultancy Ltd | Professional & scientific | 2018 |
| UTH Global Ltd | Hospitality | 2024 |
| UTP Systems Limited | Other services | 2009 |
| Utrr Limited | Wholesale & retail | 2021 |
| UV & I Limited | Wholesale & retail | 2023 |
| UV Services Ltd | Other services | 2017 |
| Uvaa Properties Ltd | Real estate | 2021 |
| Uvaa Solutions Limited | Information & communication | 2023 |
| UZI Retail Ltd | Wholesale & retail | 2025 |
| UZI Safeguarding Ltd | Administrative & support | 2024 |
| Uzitaxi Limited | Transport & logistics | 2026 |
| Uzma Beauty Ltd | Other services | 2019 |
| V & M Arrol Limited | Construction | 2014 |
| V Dhariwal Notary Public Limited | Professional & scientific | 2015 |
| V Fitt Limited | Construction | 2022 |
| V S L Consultants Limited | Real estate | 1996 |
| V&L Couriers Ltd | Transport & logistics | 2024 |
| V&M Distributors Ltd | Wholesale & retail | 2024 |
| V&S Building Ltd | Construction | 2022 |
| V&S Holdings Group Ltd | Real estate | 2026 |