| Strathmore Capital Limited | Professional & scientific | 2025 |
| Stratton House Ltd | Hospitality | 2024 |
| Stratton Oakmont Limited | Wholesale & retail | 2014 |
| Streamvector UK Limited | Information & communication | 2022 |
| Street Wise Logistics Ltd | Transport & logistics | 2026 |
| Streetwise Lettings & Property Management Ltd | Real estate | 2024 |
| Streetwise Translations Limited | Professional & scientific | 2013 |
| Stretch People Development Limited | Professional & scientific | 2012 |
| Strings Payments Ltd | Financial services | 2023 |
| Strive Assist Ltd | Health & social care | 2026 |
| Structegrity Investments Ltd | Real estate | 2024 |
| Structegrity Projects Ltd | Construction | 2009 |
| Structural Renovations Limited | Construction | 1993 |
| Structure Sight Ltd | Professional & scientific | 2025 |
| Stryd Limited | Wholesale & retail | 2025 |
| Stryve Group Limited | Real estate | 2016 |
| STS Transport World Ltd | Wholesale & retail | 2019 |
| Stuart Cameron Medical and Transport Ltd | Health & social care | 2018 |
| Stuart House Care Limited | Health & social care | 2020 |
| Studenthive Tutoring Ltd | Education | 2026 |
| Studio Glove Limited | Manufacturing | 2022 |
| Studio JAG Sihra Limited | Professional & scientific | 2021 |
| Studio Kosta Ltd | Professional & scientific | 2022 |
| Studio Late. Ltd | Wholesale & retail | 2026 |
| Studio NO26 Limited | Other services | 2018 |
| Studio Rovik Ltd | Professional & scientific | 2025 |
| Study Bits Ltd | Wholesale & retail | 2025 |
| Study Milestone Ltd | Education | 2020 |
| Stuffusell Ltd | Wholesale & retail | 2022 |
| Style Heaven UK Ltd | Wholesale & retail | 2023 |
| Style Kitchen & Bedrooms Ltd | Professional & scientific | 2022 |
| Stylecove Ltd | Wholesale & retail | 2025 |
| Styleharbor Ltd | Administrative & support | 2024 |
| Stylish Living Ltd | Manufacturing | 2024 |
| Styllish Windows Ltd. | Construction | 2017 |
| Styloo Stores Ltd | Wholesale & retail | 2015 |
| SU Brothers Properties Limited | Real estate | 2021 |
| SU WEN Herbs Limited | Administrative & support | 1996 |
| Suad a Warsama Limited | Health & social care | 2024 |
| Suave Events Limited | Hospitality | 2021 |
| SUB & Super Structures Ltd | Construction | 2026 |
| SUB Build Ltd | Construction | 2025 |
| Subfox Limited | Construction | 2024 |
| Subg Solutions Limited | Information & communication | 2014 |
| Subhan Halal Meat Ltd | Wholesale & retail | 2022 |
| Sublime Resourcing Ltd | Administrative & support | 2009 |
| Sublime Ventures Ltd | Wholesale & retail | 2025 |
| Sublimedia Limited | Information & communication | 2013 |
| Submission UK Ltd | Transport & logistics | 2019 |
| Subs Limited | Extraterritorial | 2005 |
| Substructure Developments Ltd | Construction | 2019 |
| Suburbia Photography Limited | Professional & scientific | 2007 |
| Succeed ED (2015) Ltd | Education | 2015 |
| Success IT Solutions Limited | Information & communication | 2016 |
| Suckers Limited | Hospitality | 2000 |
| Suden Homes Limited | Real estate | 2019 |
| Suede Cosmetics Ltd | Wholesale & retail | 2025 |
| SUF Solutions Ltd | Administrative & support | 2026 |
| Sufan Limited | Manufacturing | 2021 |
| Sufi International Ltd | Professional & scientific | 2024 |
| Sugar and Spice and Everything That IS Nice Ltd | Health & social care | 2022 |
| Sugarmark Holding Company Limited | Professional & scientific | 2009 |
| Suhavi Bricklaying and Construction Ltd | Construction | 2026 |
| Sujash Limited | Wholesale & retail | 2018 |
| Sukh Flower Decorations Limited | Wholesale & retail | 2022 |
| Sukh Jiven Investments Limited | Real estate | 2024 |
| Sukh Roofing Limited | Construction | 2021 |
| Sukh Staircase Limited | Construction | 2019 |
| Sukh&Sonu Construction Limited | Transport & logistics | 2024 |
| Sukhdeep Estates Limited | Real estate | 2025 |
| Sukhdev SINGH1 Ltd | Construction | 2024 |
| Sukhman Properties Limited | Real estate | 2021 |
| Sukhmani Drylining Limited | Construction | 2022 |
| Sukhnoor Trading Limited | Wholesale & retail | 2023 |
| Sukhpreet Kaur Legacy Wealth Ltd | Real estate | 2026 |
| Sukhraj Brickwork Ltd | Construction | 2021 |
| Sukhwinder Singh Ltd | Construction | 2019 |
| Sukhwinder Singh Randhawa Ltd | Transport & logistics | 2026 |
| Suleman Haulage Ltd | Transport & logistics | 2016 |
| Suleman Transport Ltd | Transport & logistics | 2021 |
| Sultan Cafe Ltd | Hospitality | 2025 |
| Sultani Autobody Ltd | Manufacturing | 2026 |
| Sultani Motors Ltd | Wholesale & retail | 2015 |
| Sumaira’S Hair & Beauty Limited | Other services | 2026 |
| Sumeet's STEP2STEP Entertainments Ltd | Arts & recreation | 2019 |
| Sumeetpal Plumbing & Build Ltd | Construction | 2025 |
| SUMEETSSTEP2STEP Limited | Arts & recreation | 2015 |
| Sumera Khan Ltd | Wholesale & retail | 2025 |
| Sumitraraj Ltd | Information & communication | 2026 |
| Summercombe OTS NO 31 Limited | Wholesale & retail | 1995 |
| Summerley Investments Limited | Professional & scientific | 2001 |
| Summit Lifestyle Management Ltd | Administrative & support | 2016 |
| Summit Payroll Services Ltd | Health & social care | 2010 |
| Summit Roofing and Guttering Ltd | Construction | 2024 |
| Summit Umbrella Limited | Administrative & support | 2024 |
| Summit Wheels Ltd | Wholesale & retail | 2026 |
| Sun Eclipse Ltd | Wholesale & retail | 2018 |
| Sun Global Realty UK Limited | Construction | 2024 |
| Sun Mortgage and Protection Limited | Financial services | 2017 |
| Sun N Shine Limited | Real estate | 2025 |