| Shelton Court Management Company (Slough) Limited | Households | 1977 |
| Shelvex Limited | Manufacturing | 1999 |
| Shen Property Management Limited | Real estate | 2017 |
| Shepherd Property Solutions Ltd | Real estate | 2017 |
| Shepic Ltd | Wholesale & retail | 2025 |
| Shepperton Splash Ltd | Arts & recreation | 2018 |
| Sher-E-Punjab Logistics Ltd | Transport & logistics | 2025 |
| Shera Gill Transport Ltd | Transport & logistics | 2023 |
| Shera Transport Ltd | Transport & logistics | 2025 |
| Shere Punjab Living Interiors Ltd | Other services | 2022 |
| Shergill Driveway Ltd | Construction | 2026 |
| Shergillz Construction Limited | Construction | 2024 |
| Sheridan Court Management (Slough) Limited | Households | 1972 |
| Sheridan Projects S E LLP | | 2017 |
| Sheridan Ward Recruitment Services Limited | Administrative & support | 2002 |
| SHERINE26 Offlicence Ltd | Wholesale & retail | 2024 |
| Sherry Enterprises Ltd | Wholesale & retail | 2019 |
| Sherwani King Ltd | Administrative & support | 2015 |
| Sherwood Asset Management Ltd | Real estate | 2020 |
| Sherwood Building Group Ltd | Construction | 2016 |
| Sherwood Court RTE Associates Limited | Extraterritorial | 2009 |
| Sheter Ltd. | Financial services | 2017 |
| Shevik Limited | Real estate | 2023 |
| Shiby Ltd | Education | 2024 |
| Shieldguard Ltd | Wholesale & retail | 2024 |
| Shienga Ltd | Real estate | 2025 |
| Shifa Hydraytion Ltd | Other services | 2026 |
| Shifa Pure and Simple Ltd | Manufacturing | 2025 |
| Shifaa Ltd | Wholesale & retail | 2021 |
| Shimmer Oceans Ltd | Wholesale & retail | 2025 |
| Shine Builders Ltd | Construction | 2026 |
| Shine Cash&Carry Ltd | Wholesale & retail | 2025 |
| Shine Healthcare Recruitment Services PVT Limited | Health & social care | 2013 |
| Shine Kitchen and Bedroom Limited | Manufacturing | 2023 |
| Shine on GEM & Jewellery Ltd | Wholesale & retail | 2022 |
| Shiner Consulting Limited | Professional & scientific | 2026 |
| Shinfield Village Holdings Ltd | Real estate | 2022 |
| Shingar Info Ltd | Real estate | 2015 |
| Shingar Jewellers Limited | Wholesale & retail | 2006 |
| Shinzer Industries Ltd | Wholesale & retail | 2023 |
| Shinzer Investments Ltd | Real estate | 2015 |
| Shiolou Group Limited | Wholesale & retail | 2019 |
| Ship Bravo Ltd | Wholesale & retail | 2024 |
| Shiperoo-Uk Ltd | Wholesale & retail | 2022 |
| Shipleys Foodservice Limited | Hospitality | 2008 |
| Shipright Limited | Construction | 2013 |
| Shir Graphic Limited | Professional & scientific | 2024 |
| Shireen Faisal Traders Ltd | Wholesale & retail | 2024 |
| Shital Gaurang Limited | Health & social care | 2012 |
| Shiv Property Limited | Real estate | 2024 |
| Shiv SAI Technologies Ltd | Information & communication | 2012 |
| Shiva Consulting Private Limited | Information & communication | 2016 |
| Shivana Global Ltd | Wholesale & retail | 2025 |
| Shivayaa Limited | Wholesale & retail | 2017 |
| Shivkrupa Properties Ltd | Real estate | 2023 |
| Shivraee Limited | Education | 2020 |
| SHL Roofing and Building Ltd | Construction | 2025 |
| SHM Logistics Ltd | Transport & logistics | 2026 |
| Shmaila Modern Wear Ltd | Wholesale & retail | 2019 |
| SHO Verify UK Ltd | Administrative & support | 2025 |
| Shoc, Slough Homeless - OUR Concern | Health & social care | 1998 |
| Shodesh UK Limited | Hospitality | 2016 |
| Shoe City Slough Ltd | Wholesale & retail | 2021 |
| Shoe World Hounslow Ltd | Wholesale & retail | 2013 |
| Sholé Software Solutions Ltd | Information & communication | 2018 |
| Shop & Stop Limited | Wholesale & retail | 2018 |
| Shop Smarter Ltd | Wholesale & retail | 2025 |
| Shop With AM Ltd | Wholesale & retail | 2026 |
| Shop With ZEE Ltd | Wholesale & retail | 2025 |
| Shopandtrend Ltd | Wholesale & retail | 2022 |
| Shopeefy Store Limited | Wholesale & retail | 2019 |
| Shopelo Ltd | Wholesale & retail | 2026 |
| Shopglide Ltd | Wholesale & retail | 2025 |
| Shopi Shopper Ltd | Wholesale & retail | 2025 |
| Shopiphy Ltd. | Wholesale & retail | 2026 |
| Shoplia Stores Ltd | Wholesale & retail | 2025 |
| Shoplyf. Ltd | Wholesale & retail | 2025 |
| Shopping Spree Ltd | Wholesale & retail | 2023 |
| Shoptarctica Ltd | Wholesale & retail | 2020 |
| Shopvault Ltd | Wholesale & retail | 2023 |
| Shopvoraa Ltd | Wholesale & retail | 2026 |
| Shopy Trolley Limited | Wholesale & retail | 2021 |
| Shoviz Ltd | Administrative & support | 2017 |
| Showard Ltd | Financial services | 2024 |
| Shown Limited | Wholesale & retail | 2025 |
| Shown Tradings Limited | Energy | 2025 |
| Showtime Deals Ltd | Wholesale & retail | 2025 |
| Shree Nidhi Fresh Bites Ltd | Wholesale & retail | 2024 |
| Shree Radhe Cakebox Limited | Wholesale & retail | 2020 |
| Shreea Limited | Professional & scientific | 2018 |
| Shreeji Health Limited | Public administration | 2024 |
| Shreetha Care Ltd | Real estate | 2015 |
| Shri Ankaalamman PVT Ltd | Hospitality | 2026 |
| Shri Beauty Bar Ltd | Other services | 2024 |
| Shri Krishna SAI Foods Ltd | Wholesale & retail | 2023 |
| Shri Sadgurukripa Limited | Wholesale & retail | 2011 |
| Shri Sannidhi Foods Limited | Wholesale & retail | 2021 |
| Shrihari IT Solutions Ltd | Information & communication | 2024 |
| Shrill Services Limited | Professional & scientific | 2013 |
| Shrinam Investments Ltd | Real estate | 2022 |