| Saviour Energy Solutions Ltd | Professional & scientific | 2014 |
| Saviour Healthcare Limited | Health & social care | 2014 |
| Saviour Properties Ltd | Real estate | 2021 |
| Saviour Services Ltd | Transport & logistics | 2013 |
| Savoir Living Limited | Real estate | 2023 |
| Savoy Partnership Ltd | Real estate | 2013 |
| Savreet's Consulting Limited | Information & communication | 2018 |
| Savs MD Ltd | Wholesale & retail | 2024 |
| Savvy Cat Limited | Information & communication | 1982 |
| Savvy Programmers Limited | Wholesale & retail | 2016 |
| SAW Consultancy Services Ltd | Professional & scientific | 2024 |
| Sayed Property Limited | Real estate | 2025 |
| Sayeda Holdings Limited | Financial services | 2025 |
| Sayeda Logistics Ltd | Transport & logistics | 2020 |
| Sayers Construction Ltd | Construction | 2011 |
| Sayhar Limited | Administrative & support | 2023 |
| Saysa Ltd | Wholesale & retail | 2023 |
| Sayyadain M Limited | Real estate | 2025 |
| SB Furniture & Decor Ltd. | Wholesale & retail | 2025 |
| SB Planning Services Ltd | Construction | 2011 |
| SB Project Solutions Ltd | Professional & scientific | 2024 |
| SBA Properties Ltd | Real estate | 2012 |
| SBA Vision Property Services Limited | Real estate | 2016 |
| Sbas Tax Ltd | Professional & scientific | 2023 |
| Sbfour Limited | Health & social care | 2018 |
| SBH Construction Ltd | Construction | 2024 |
| SBM Solutions Limited | Information & communication | 2022 |
| SBR Consultants Ltd | Other services | 2013 |
| SBR Technologies Limited | Information & communication | 2018 |
| SBS Refrigration Limited | Professional & scientific | 2019 |
| SBT Consulting Limited | Information & communication | 2009 |
| SBT Properties Ltd | Real estate | 2017 |
| SBX Property Ltd | Real estate | 2025 |
| SC Asset Management Limited | Arts & recreation | 2026 |
| SC Garg Limited | Health & social care | 2010 |
| SC Housing Ltd | Real estate | 2019 |
| SC IT Consultancy Limited | Information & communication | 2012 |
| SC Technologies Global (PVT) Limited | Information & communication | 2011 |
| SCA Trafalgar Limited | Health & social care | 2019 |
| Scaanan Company Limited | Information & communication | 2019 |
| Scala Technologies Ltd | Information & communication | 2019 |
| Scalable Property Solutions Limited | Real estate | 2018 |
| Scale TEC Ltd | Education | 2019 |
| Scale With Flair Ltd | Administrative & support | 2025 |
| Scaleforce AI Ltd | Information & communication | 2025 |
| Scalesbars Limited | Hospitality | 2025 |
| Scan Global Logistics (UK) Ltd | Transport & logistics | 1991 |
| Scarborough Way Residents Company Limited | Households | 2009 |
| Scarlet Impex Limited | Wholesale & retail | 2024 |
| Scav Limited | Administrative & support | 2003 |
| SCD Insights Limited | Professional & scientific | 2020 |
| Scene IT Done IT Ltd | Professional & scientific | 2021 |
| Scently Ltd | Manufacturing | 2019 |
| Scentrd Limited | Wholesale & retail | 2026 |
| Scents for Your Senses Ltd | Wholesale & retail | 2022 |
| Scents on Trial Limited | Wholesale & retail | 2025 |
| Schb Services Ltd | Professional & scientific | 2022 |
| Schemtech Limited | Professional & scientific | 2007 |
| Schezwan Street Ltd | Hospitality | 2025 |
| School of Business and Management London Ltd | Education | 2025 |
| School Spider Limited | Information & communication | 2013 |
| Scientific Graphics Limited | Professional & scientific | 2006 |
| Scion Jewellers Limited | Manufacturing | 2024 |
| Scorr Ltd | Wholesale & retail | 2022 |
| Scotch & Ginger Limited | Professional & scientific | 2016 |
| Scott Investment Partners LLP | | 2012 |
| Scott Yard Ltd | Wholesale & retail | 2021 |
| Scotts Motors Ltd | Wholesale & retail | 2025 |
| Scouts Services Limited | Professional & scientific | 2017 |
| Scrapape Ltd | Hospitality | 2025 |
| Screen of Space Ltd | Manufacturing | 2023 |
| Scube IT Solutions Ltd | Information & communication | 2023 |
| Sculpt Haus Aesthetics Ltd. | Other services | 2024 |
| Sculpt Reformer Pilates Ltd | Health & social care | 2025 |
| SD Aviation Ltd | Manufacturing | 2025 |
| SD Maini Ltd | Health & social care | 2019 |
| SD Technologies PVT Ltd | Information & communication | 2022 |
| SD Wines Ltd | Wholesale & retail | 2021 |
| SDE Enterprise Ltd | Wholesale & retail | 2024 |
| Sdec Property Ltd | Real estate | 2025 |
| SDJ Consulting Limited | Information & communication | 2010 |
| SDK Medical Services Limited | Health & social care | 2023 |
| SDM Solutions Limited | Administrative & support | 2014 |
| SDM Square Properties Limited | Real estate | 2023 |
| SDR Transport Limited | Transport & logistics | 2025 |
| Se-Ba Interiors Ltd | Construction | 2024 |
| Sea Technology UK Ltd | Other services | 2013 |
| Seahorse Amphibious Vehicles Ltd | Transport & logistics | 2012 |
| Seahorse Manufacturing Limited | Manufacturing | 2024 |
| Seahorse Vehicles Limited | Transport & logistics | 2024 |
| Seamar Properties Ltd | Real estate | 2021 |
| Seanic Limited | Wholesale & retail | 2009 |
| Seaquest-Newquay Limited | Construction | 2013 |
| Search Promotional Merchandise Limited | Professional & scientific | 1988 |
| Sears Holdings Limited | Hospitality | 2025 |
| Season Fruit and VEG Ltd | Wholesale & retail | 2015 |
| Seasonal IT Solutions Ltd | Transport & logistics | 2014 |
| Seclair Care Company Limited | Health & social care | 2023 |
| Secrets Lounge Ltd | Hospitality | 2021 |
| Secriss Ltd | Construction | 2022 |