| Deeptrace Consulting Limited | Information & communication | 2025 |
| Deeside Plant Hire Ltd | Transport & logistics | 2021 |
| Deniz Auto Group Ltd | Wholesale & retail | 2025 |
| Denno Trading Limited | Wholesale & retail | 2019 |
| Derek Mason Transport Limited | Transport & logistics | 2005 |
| Design by Gavriela Ltd | Manufacturing | 2023 |
| Despard Properties Ltd | Real estate | 2007 |
| DGM Controls Limited | Manufacturing | 2022 |
| Digident Laboratories Ltd | Manufacturing | 2025 |
| Dimana 19 Ltd | Transport & logistics | 2020 |
| Direct Training (NW) Ltd | Education | 2012 |
| Direct Transport Services Ltd | Transport & logistics | 2018 |
| DIRECT365ONLINE Limited | Administrative & support | 2005 |
| Distinguished Brands (UK) Ltd | Professional & scientific | 2018 |
| Ditacar Transport Ltd | Transport & logistics | 2021 |
| Divine Days Community CIC | Health & social care | 2013 |
| DJF Flooring Ltd | Construction | 2021 |
| Djkb Limited | Wholesale & retail | 2018 |
| DJM Recruitment Limited | Extraterritorial | 2013 |
| DJX Transport Limited | Transport & logistics | 2016 |
| DK & RS Holdings (UK) Limited | Financial services | 2026 |
| Dlicious Treats( Deedew) Ltd | Wholesale & retail | 2026 |
| DLR Education Limited | Administrative & support | 2023 |
| Dorarge CD Trans Ltd | Transport & logistics | 2019 |
| Double Dutch Hotels Limited | Hospitality | 2018 |
| Dowls Construction Ltd | Construction | 2022 |
| Dowls Developments Ltd | Construction | 2024 |
| Dowls Granville Park East Ltd | Real estate | 2026 |
| Dowls Mill Cottage Ltd | Real estate | 2025 |
| DPH Joinery (NW) Limited | Construction | 2013 |
| DR Transformations Ltd | Health & social care | 2023 |
| Dragonfly Fire and Security Ltd | Construction | 2021 |
| Dream Team Play Structures Ltd | Manufacturing | 2021 |
| Dream Wizard Limited | Professional & scientific | 2006 |
| Dream-Makers Showtime CIC | Education | 2024 |
| Drew Finance Support Ltd | Financial services | 2025 |
| Driverlink Training (NW) Limited | Education | 2010 |
| Drivewayworkout Limited | Arts & recreation | 2025 |
| Dropt Ltd | Information & communication | 2026 |
| Dslmc Ltd | Transport & logistics | 2017 |
| DTC Enterprises Ltd | Information & communication | 2015 |
| DTL3 Ltd | Wholesale & retail | 2023 |
| DTR Property & Development Ltd | Construction | 2023 |
| Dynamic Battery Services Limited | Wholesale & retail | 1994 |
| E & C Roofing Services Ltd | Construction | 2016 |
| East END Housing Management Ltd | Households | 2019 |
| East Star Exports Limited | Other services | 2016 |
| Easyfit Blinds Limited | Manufacturing | 2010 |
| Easyfixit Ltd | Professional & scientific | 2019 |
| Easylift Materials Handling Limited | Wholesale & retail | 2016 |
| EAT ME 1 Limited | Hospitality | 2022 |
| Eccleston Properties Limited | Real estate | 2019 |
| Ecommerce Platinum Ltd | Wholesale & retail | 2021 |
| Ecotex Engineering Systems Ltd | Manufacturing | 2013 |
| ECR Investments Limited | Financial services | 2017 |
| Eden & Co Estates Limited | Real estate | 2026 |
| Edgehill Property Finance Ltd | Financial services | 2024 |
| EDM Engineering Ltd | Construction | 2020 |
| Edmund Bell & Co., Limited | Manufacturing | 2008 |
| Edmundson Haulage Holdings Ltd. | Other services | 1999 |
| EDU Advisors UK Limited | Administrative & support | 2024 |
| EDU Bridge Limited | Wholesale & retail | 2025 |
| Edwards Energy Direct Ltd | Information & communication | 2015 |
| EF Property Lettings Ltd | Real estate | 2022 |
| EFA Solutions Ltd | Wholesale & retail | 2024 |
| EGM Properties Ltd | Real estate | 2018 |
| Eighth Fragment Tilers Limited | Construction | 2024 |
| Ekadant Limited | Construction | 2025 |
| Ekhoa Group Ltd | Wholesale & retail | 2026 |
| El-Chez Ltd | Wholesale & retail | 2023 |
| Electric-Cal Ltd | Construction | 2014 |
| Electrical & Environmental Services Ltd | Construction | 2002 |
| Elegant Garden Maintenance Limited | Construction | 2016 |
| Elevate BPM Solutions Ltd | Professional & scientific | 2018 |
| Elevate Spaces Construction Ltd | Construction | 2025 |
| Elevated Holdings Limited | Real estate | 2022 |
| Elevated JAM Tracks Limited | Information & communication | 2020 |
| Elite Property Lettings Ltd | Real estate | 2026 |
| Elite Taping/Jointing Ltd | Construction | 2024 |
| Ellangate Developments Limited | Real estate | 1984 |
| Ellyn Ltd | Wholesale & retail | 2023 |
| ELM House (UK) Ltd | Other services | 2014 |
| Elston Products Limited | Professional & scientific | 2025 |
| EM Care Ltd | Wholesale & retail | 2026 |
| Embryo Genesis Ltd | Professional & scientific | 2025 |
| Empire Painting&Decorating Ltd | Construction | 2025 |
| Empower the Invisible Project C.I.C. | Education | 2019 |
| Energy Plus NW Ltd | Construction | 2024 |
| Engtech Services (North West) Limited | Professional & scientific | 2017 |
| Ennerdale 22 Limited | Households | 2021 |
| Enriles Beauty Ltd | Other services | 2021 |
| Enviroseal Containment Solutions Limited | Construction | 2021 |
| Envision Commercial Properties Limited | Real estate | 2021 |
| Envision Media Ltd | Professional & scientific | 2012 |
| Equicure Ltd. | Manufacturing | 2016 |
| Erlson Precision Components Limited | Manufacturing | 1973 |
| Erlson Precision Holdings Limited | Manufacturing | 2010 |
| ESG Driver Training Ltd | Education | 2026 |
| Espectro Printing Services Ltd | Manufacturing | 2024 |
| Esther a Coaching Limited | Other services | 2020 |