| Two Double US Ltd | Hospitality | 2025 |
| Two Words Digital Limited | Information & communication | 2025 |
| TY Coch Restaurants Limited | Administrative & support | 2012 |
| Typocolor Designs Limited | Manufacturing | 2008 |
| U.I.D.D Works Ltd | Construction | 2025 |
| U.S.B Nationwide Limited | Professional & scientific | 2025 |
| UB Properties Ltd | Real estate | 2023 |
| UDC Property Limited | Real estate | 2026 |
| UK 3V3S Ltd | Arts & recreation | 2025 |
| UK Carbody Limited | Wholesale & retail | 2000 |
| UK Online Group Ltd | Information & communication | 2022 |
| UK Pixel Limited | Information & communication | 2018 |
| UKI Express Transport Limited | Transport & logistics | 2007 |
| UKI Holdings Limited | Administrative & support | 2016 |
| UKI Property Group Limited | Real estate | 2025 |
| UKI Warehousing Limited | Transport & logistics | 2005 |
| Unicorn Domestic Limited | Administrative & support | 2020 |
| Unique Integrated Systems Limited | Administrative & support | 1991 |
| Uniqueu Custom Designs Ltd | Manufacturing | 2024 |
| Uniting Paths CIC | Education | 2025 |
| Untaught State Ltd | Wholesale & retail | 2018 |
| Upholland Barbers Limited | Other services | 2026 |
| Upholland Kennels Ltd | Other services | 2023 |
| Upholland Property Company Ltd | Real estate | 2024 |
| UPS Building & Maintenance Limited | Construction | 2007 |
| UPS Investments Limited | Financial services | 2018 |
| Urban Asset Developments Ltd | Real estate | 2025 |
| Urban Hair Skelmersdale Limited | Other services | 2020 |
| Urgent Dental Care Limited | Health & social care | 2006 |
| Used Bodyshop Equipment Ltd | Other services | 2017 |
| Uthink New Horizons CIC | Education | 2010 |
| Uthink People Developing People | Education | 2012 |
| V&A Lettings Properties Ltd | Real estate | 2026 |
| V&N Logistics Ltd | Transport & logistics | 2023 |
| V&P Transport Ltd | Transport & logistics | 2017 |
| V15 Ltd | Hospitality | 2023 |
| Vale Cost Management Limited | Construction | 2017 |
| Vanguard Auto Locksmith & Van Security Ltd | Administrative & support | 2025 |
| Vanguard Construction Solutions Ltd | Construction | 2022 |
| Vape Juice Direct Distro Ltd | Wholesale & retail | 2022 |
| Vapeflava Ltd | Wholesale & retail | 2019 |
| Vasc Aminian Limited | Health & social care | 2022 |
| Vastu Vidya Ltd | Real estate | 2022 |
| VB GAS and Heating Limited | Construction | 2025 |
| VEE Associates Limited | Hospitality | 2012 |
| VEE Bidco Limited | Financial services | 2025 |
| VEE Midco 1 Limited | Financial services | 2025 |
| VEE Midco 2 Limited | Financial services | 2025 |
| Vellum Bathrooms Ltd | Construction | 2026 |
| Velpro Solutions Ltd | Administrative & support | 2020 |
| Venilde & Sons Limited | Wholesale & retail | 1979 |
| Venueburst Ltd | Real estate | 2024 |
| Veridion Consulting Limited | Professional & scientific | 2025 |
| Vertigo Recruitment Ltd | Administrative & support | 2025 |
| Vessel Management Ltd | Mining & quarrying | 2015 |
| Vibrant Sky Records Limited | Arts & recreation | 2019 |
| Virtue Technologies Limited | Information & communication | 2006 |
| Vision Connected Ltd | Wholesale & retail | 2001 |
| Vitacure Ltd. | Manufacturing | 2016 |
| VJP Limited | Wholesale & retail | 2022 |
| Vmbh Ltd | Transport & logistics | 2025 |
| Volta Electrical Limited | Construction | 2018 |
| Voodoo Boutique Outlet Ltd | Wholesale & retail | 2016 |
| Vulpes Eniera Ltd | Financial services | 2025 |
| Vyrolabs Ltd | Information & communication | 2026 |
| W & J Rigby Limited | Transport & logistics | 2014 |
| W L Polymer Limited | Water & waste | 2019 |
| Walk on Design Limited | Extraterritorial | 2004 |
| Walker Engineering (NW) Limited | Manufacturing | 2003 |
| Walker Engineering Holdings Limited | Manufacturing | 2025 |
| Walthew Green Association (LBG) Limited | Water & waste | 2019 |
| Warm Connections Ltd | Construction | 2019 |
| Web Solution Flores Ltd | Information & communication | 2025 |
| Wellmeing Limited | Wholesale & retail | 2020 |
| West Cheshire Carpets Limited | Wholesale & retail | 2015 |
| West Lancashire Crisis and Information Centre | Health & social care | 1997 |
| West Lancashire Engineering Ltd | Manufacturing | 2018 |
| West Lancashire Junior Football League Ltd | Arts & recreation | 2025 |
| West Lancashire Niche Fragrance Group Limited | Wholesale & retail | 2025 |
| West Lancs BIN Cleaning Ltd | Administrative & support | 2023 |
| West Lancs Butchers Ltd | Manufacturing | 2011 |
| West Lancs Diner Ltd | Hospitality | 2021 |
| West Lancs Functions Ltd | Hospitality | 2024 |
| West Lancs Hackneys Ltd | Transport & logistics | 2016 |
| West Lancs Logistics Ltd | Administrative & support | 2023 |
| West Lancs Peer Support | Administrative & support | 2007 |
| West Lancs Precision (Holdings) Limited | Administrative & support | 2017 |
| Westgate Flooring Supply Limited | Construction | 2018 |
| Westgate Tyre & Service Centre Ltd | Wholesale & retail | 2013 |
| Westhaven Mews Managment Company Limited | Real estate | 2017 |
| Westhead Caravans Ltd | Hospitality | 2017 |
| Weston Truck & Excavator Ltd | Transport & logistics | 2005 |
| What's the Script Ltd | Professional & scientific | 2025 |
| White House Warehousing Ltd | Transport & logistics | 2019 |
| White Lion (Skelmersdale) Ltd | Hospitality | 2025 |
| White Moss Pavilion Limited | Hospitality | 2025 |
| Whittington Broadway Ltd | Hospitality | 2024 |
| Wide Cross Service Station Limited | Wholesale & retail | 1999 |
| Wigan Logs Direct Ltd | Agriculture & fishing | 2025 |
| Willmore Properties Limited | Real estate | 2020 |