| Dhmj Property Ltd | Real estate | 2026 |
| Digby House Management Company (Skegness) Limited | Real estate | 2018 |
| Digital Cryogenics Limited | Information & communication | 2016 |
| Dimaf Ltd | Health & social care | 2018 |
| Direct Selling Success Ltd | Other services | 2023 |
| DJ Robinson Engineering Services Ltd | Professional & scientific | 2021 |
| Djcl Ltd | Arts & recreation | 2026 |
| DK Motor Group Ltd | Wholesale & retail | 2022 |
| Dksj Properties Limited | Real estate | 2017 |
| DM Trading Limited | Hospitality | 2012 |
| DMA Project Management Ltd | Construction | 2019 |
| DMC Motors Limited | Wholesale & retail | 2012 |
| Dodelivery Ltd | Information & communication | 2020 |
| DOM Huga Ltd | Information & communication | 2017 |
| Double SIX Leisure Limited | Arts & recreation | 2022 |
| Dragon House YUN Limited | Hospitality | 2022 |
| Dragon Virtual Assistants Limited | Administrative & support | 2017 |
| Dusemond Study Programmes Ltd | Education | 2015 |
| E G Banham & Sons Limited | Agriculture & fishing | 2011 |
| E.Wrisdale & Sons,Limited | Agriculture & fishing | 1949 |
| Ealing Electronics Limited | Manufacturing | 2001 |
| East Coast Fish & Chips Limited | Hospitality | 2024 |
| East Coast Holidays Ltd | Hospitality | 2026 |
| East Coast Plumbing and Heating Ltd | Construction | 2022 |
| East Coast Satellites Limited | Wholesale & retail | 2013 |
| East Coast Sundecks Ltd | Manufacturing | 2018 |
| East Coast Vacations Limited | Hospitality | 2025 |
| East Lincs Electrical Ltd | Construction | 2006 |
| East Lincs Heating and Plumbing Services Ltd | Construction | 2025 |
| East Lincs Investments Ltd | Real estate | 2017 |
| East Lincs Renewables Ltd | Construction | 2023 |
| East Lindsey Flooring Ltd | Wholesale & retail | 2026 |
| East Lindsey Indoor Bowls Club (Skegness & District) Limited | Arts & recreation | 1978 |
| East Park Leisure Limited | Hospitality | 2003 |
| EAST2WEST Holidays Ltd | Hospitality | 2025 |
| Easy Shop & Vape Shop Ltd | Wholesale & retail | 2025 |
| Eclipse Executive Coaching and Training Ltd | Other services | 2016 |
| Ecogen Renewables (Lincs) Ltd | Construction | 2025 |
| Eden Developments and Property UK Ltd | Construction | 2026 |
| Educational Parks Limited | Education | 2024 |
| Edwin George Limited | Professional & scientific | 2023 |
| EHB Homes Limited | Real estate | 2024 |
| Electrical MEC Ltd | Construction | 2025 |
| Electrotechnical Services Ltd | Construction | 2024 |
| Elele Limited | Hospitality | 2015 |
| Eleventione Ltd | Professional & scientific | 2025 |
| Elliott Family Property Investments Ltd | Real estate | 2024 |
| Elliott Group Holdings Ltd | Financial services | 2024 |
| Elysium International Cuisine Ltd | Hospitality | 2019 |
| Emir CAN Home Ltd | Real estate | 2023 |
| Empire Hospitality Skegness Limited | Hospitality | 2025 |
| Empire Skegness Limited | Arts & recreation | 2015 |
| Endo Collects Ltd | Wholesale & retail | 2021 |
| Engage Legal Consulting Limited | Professional & scientific | 2013 |
| Entertainment & Artiste Consultancy Ltd | Arts & recreation | 2017 |
| Environmental Quality Limited | Water & waste | 2016 |
| Even Flow (Skegness) Holdings Limited | Financial services | 2025 |
| Even Flow (Skegness) Limited | Arts & recreation | 2014 |
| Everingtons Lane Services Ltd | Manufacturing | 2025 |
| Evie Toombes Foundation Ltd | Arts & recreation | 2018 |
| Extralean Limited | Wholesale & retail | 2010 |
| Ezcx Consulting Limited | Construction | 2024 |
| F Simpson and SON Limited | Agriculture & fishing | 2015 |
| Fabexstore Ltd | Wholesale & retail | 2022 |
| Facial Attraction (Skegness) Ltd | Wholesale & retail | 2004 |
| Fairhaven Fields Ltd | Hospitality | 2021 |
| Fantasy Baby & Children's Wear Ltd | Wholesale & retail | 2019 |
| Fardy Ltd | Hospitality | 2025 |
| Fashion Comes First Ltd | Wholesale & retail | 2018 |
| Faulkers Lakes Ltd | Hospitality | 2013 |
| Fedo Group Ltd | Wholesale & retail | 2025 |
| Femson Healthcare Services Limited | Health & social care | 2023 |
| Ferensway Hotels Limited | Real estate | 2016 |
| Fibreactive Fibreglass Roofing Ltd | Construction | 2017 |
| Fifth Element Enterprise Ltd | Information & communication | 2019 |
| Finesse Auto Body Centre Limited | Wholesale & retail | 2023 |
| Fiona Bateman Interiors Ltd | Construction | 2022 |
| Firbeck Properties Limited | Real estate | 1994 |
| Firetruck Communications Limited | Administrative & support | 2002 |
| First Inns Limited | Hospitality | 1997 |
| Five Sailed Windmill Limited | Manufacturing | 2003 |
| Flame Curry and Kebab House Limited | Hospitality | 2025 |
| Flare Leadership and Consulting Ltd | Professional & scientific | 2024 |
| Flexroad UK Limited | Administrative & support | 2021 |
| Floyd Lodge Limited | Hospitality | 2021 |
| Foopod Limited | Wholesale & retail | 2025 |
| Footy Prints Ltd | Wholesale & retail | 2025 |
| Foreman Catering Limited | Hospitality | 2025 |
| Foreshore Leisure Limited | Wholesale & retail | 2007 |
| Forsight (Lincolnshire) Limited | Wholesale & retail | 2009 |
| Foster Benson Associates Ltd | Construction | 2023 |
| Foundations and Buildings Limited | Construction | 2005 |
| Four Squires Property Limited | Real estate | 2026 |
| Fourteen Agrinsect Limited | Agriculture & fishing | 2020 |
| Fresh Start Cleaning Services Lincolnshire Ltd | Other services | 2023 |
| Frosty Models UK Ltd | Wholesale & retail | 2025 |
| FU Yuan Chinese Skegness Limited | Hospitality | 2018 |
| Funworld Limited | Arts & recreation | 1977 |
| Fury Autoworx Limited | Wholesale & retail | 2016 |
| G Barker & Sons Limited | Construction | 2003 |