| Russell Property Group Limited | Real estate | 2019 |
| Russell Property Investments Limited | Real estate | 2020 |
| Rustic Sun Limited | Other services | 2025 |
| Ruxley Car Spa Ltd | Administrative & support | 2021 |
| Ruxley Design Services Limited | Professional & scientific | 2021 |
| Ruxley Manor Garden Centre Ltd | Wholesale & retail | 1974 |
| Ruxley Rooms Express Ltd | Hospitality | 2020 |
| Ruyton Holdings Ltd | Real estate | 2020 |
| Ruyton Property Holdings Ltd | Real estate | 2021 |
| RW Crash Repairs & Vehicle Paintwork Limited | Wholesale & retail | 2012 |
| RW Crash Repairs Ltd | Wholesale & retail | 2024 |
| Ryall and Edwards Limited | Extraterritorial | 2016 |
| Ryan Family Holdings Limited | Financial services | 2018 |
| Ryan PO Consultancy Limited | Professional & scientific | 2024 |
| Rysco Construction Limited | Construction | 2018 |
| RZ Barbers Ltd | Other services | 2026 |
| S & G Mechanical Installations Limited | Administrative & support | 2018 |
| S & J Webster (London) Ltd | Construction | 2017 |
| S & L Jewellery Limited | | 1981 |
| S & L Taylor Consultants Limited | Administrative & support | 2012 |
| S & S Contract Cleaning Services Limited | Administrative & support | 1981 |
| S and C Haines Family Ventures Limited | Financial services | 2025 |
| S and F Elec Limited | Construction | 2019 |
| S Biler Limited | Manufacturing | 2013 |
| S E Fixing Ltd | Administrative & support | 2009 |
| S G N Electrical Services Ltd | Construction | 2007 |
| S J Signs Limited | Administrative & support | 2004 |
| S L N Health Limited | Health & social care | 2013 |
| S R Contracts Limited | Construction | 2018 |
| S R Dent Limited | Health & social care | 2023 |
| S R Patterns Limited | Other services | 2015 |
| S Spring Electricals Limited | Construction | 2022 |
| S T Resurfacing Limited | Construction | 2008 |
| S Waters Limited | Professional & scientific | 2020 |
| S&L Prime Property Ltd | Real estate | 2025 |
| S&S Business Development Ltd | Construction | 2022 |
| S.Rofe Maintenance Limited | Construction | 2017 |
| S13 Consulting Ltd | Information & communication | 2024 |
| S42 Group Ltd | Financial services | 2026 |
| S42 Labs Ltd | Information & communication | 2025 |
| SA Carwash and Valeting Limited | Administrative & support | 2020 |
| Sadler Roofing Limited | Construction | 2015 |
| Sadrettin Investments Ltd | Administrative & support | 2023 |
| Safah Trading Ltd | Wholesale & retail | 2025 |
| Safe Path Care Ltd | Administrative & support | 2023 |
| Safety Label System Limited | Extraterritorial | 2016 |
| Sagaris Management Limited | Professional & scientific | 2024 |
| Saige Pilates Studio Limited | Arts & recreation | 2025 |
| Sailaway London Limited | Wholesale & retail | 2024 |
| Salami Services (UK) Limited | Administrative & support | 2012 |
| Salesfortt Limited | Wholesale & retail | 2025 |
| Sallar Trading Ltd | Wholesale & retail | 2025 |
| Salon Aitch Ltd | Other services | 2016 |
| Salt Club Consulting Limited | Administrative & support | 2017 |
| Saluki Limited | Hospitality | 2023 |
| Salus House Ltd | Arts & recreation | 2024 |
| Salusbury Consulting Limited | Real estate | 2021 |
| SAM Stewart Construction Ltd | Construction | 2025 |
| SAM Stock Associates Limited | Administrative & support | 2013 |
| Samantha Watson Osteopathy Limited | Health & social care | 2018 |
| Samir F Abdelghaffar Ltd | Health & social care | 2018 |
| Sampson-Law Consultancy Ltd | Professional & scientific | 2021 |
| Samuel Burrin Limited | Information & communication | 2021 |
| Samuel Williams Production Limited | Information & communication | 2018 |
| SAN Marketing Limited | Professional & scientific | 2013 |
| SAN Telmo Limited | Hospitality | 2006 |
| Sanamera Limited | Real estate | 2025 |
| Sanctum Landscapes Ltd | Administrative & support | 2020 |
| Sand Swallow Consulting Limited | Construction | 2017 |
| Sandi Residential Investments Limited | Real estate | 2021 |
| Sandl Property Holdings Ltd | Real estate | 2026 |
| Sandoldn Ltd | Administrative & support | 2018 |
| Sankofa Estates Group Ltd | Real estate | 2026 |
| Santé Homes Limited | Construction | 2021 |
| Santé Properties Limited | Construction | 2016 |
| Sapper Holdings Limited | Construction | 2023 |
| Sapphire Recruitment Solutions Ltd | Information & communication | 2025 |
| Saps UK Energy Consultants Ltd | Professional & scientific | 2020 |
| SAR Electrical Contractors Limited | Construction | 2017 |
| Sarah G Coaching Ltd | Other services | 2025 |
| Sarbex Plumbing and Heating Ltd | Construction | 2026 |
| Sarvatra Futuretech Ltd | Information & communication | 2024 |
| Sash Tech Windows Ltd | Administrative & support | 2020 |
| Saunders Abbott Ltd | Wholesale & retail | 2017 |
| Saville and Otley Limited | Manufacturing | 2012 |
| Saya Consultancy Limited | Professional & scientific | 2019 |
| SBK Consultancy Solutions Ltd | Professional & scientific | 2025 |
| SBP (Bexleyheath) Ltd | Wholesale & retail | 2016 |
| SC Consulting Group Ltd | Professional & scientific | 2022 |
| SC Power & Data Ltd | Construction | 2005 |
| Scallywags Dog Grooming Limited | Other services | 2020 |
| Scanprobe Techniques Limited | Manufacturing | 1992 |
| Scarlet and Rose Limited | Wholesale & retail | 2026 |
| School of International Futures Limited | Professional & scientific | 2011 |
| Schoolsout (South) Limited | Health & social care | 2004 |
| SCI Construction Group Limited | Manufacturing | 2019 |
| Scott James Mitchell Ltd | Information & communication | 2021 |
| Scott Robinson (UK) Limited | Administrative & support | 2014 |
| SD Plastering and Rendering Services Limited | Construction | 2026 |
| SDH Travel Limited | Administrative & support | 2002 |