| Shire Cleaning Solutions Ltd | Administrative & support | 2024 |
| Shire Digital Ltd | Information & communication | 2025 |
| Shire Holiday Cottages Limited | Real estate | 2023 |
| Shire Roofing and Building Services Ltd | Construction | 2023 |
| Shire Stairlifts Limited | Construction | 2008 |
| Shire Stays Limited | Real estate | 2025 |
| Shire Weddings & Events Ltd | Hospitality | 2026 |
| Shiretech Services Limited | Information & communication | 2026 |
| Shirewood Developments Limited | Households | 2025 |
| Shirley Crescent Residents Association Limited | Households | 1991 |
| Shirley Grove Management Company Limited | Households | 1993 |
| Shisha Lounge Shrewsbury 1 Limited | Hospitality | 2025 |
| SHK Medical Services Limited | Health & social care | 2024 |
| Shobdon Growers Limited | Agriculture & fishing | 2021 |
| Shoot on Sight TV Ltd. | Information & communication | 2018 |
| Shoothill Limited | Information & communication | 2006 |
| Shopbiz Ltd | Wholesale & retail | 2024 |
| Shortroundfilmclub Ltd | Wholesale & retail | 2025 |
| Shotton Hall Estate Limited | Households | 2014 |
| Show Technical Ltd | Administrative & support | 2019 |
| Showground Holdings Limited | Professional & scientific | 2025 |
| Shradale Limited | Agriculture & fishing | 2015 |
| Shraden Holdings Limited | Real estate | 2019 |
| Shree Kumari Limited | Real estate | 2025 |
| Shree Pashupati Limited | Wholesale & retail | 2025 |
| Shrewd Industrial Limited | Wholesale & retail | 2023 |
| Shrewsbury 3A Limited | Hospitality | 2017 |
| Shrewsbury Accounting Services Ltd | Professional & scientific | 2003 |
| Shrewsbury Airport Taxis Limited | Transport & logistics | 2018 |
| Shrewsbury Arena Services (SAS) Ltd | Arts & recreation | 2019 |
| Shrewsbury Arts Trail CIC | Arts & recreation | 2022 |
| Shrewsbury Bathrooms Ltd | Construction | 2021 |
| Shrewsbury Bookkeeping Ltd | Professional & scientific | 2022 |
| Shrewsbury Business Consulting Ltd | Professional & scientific | 2018 |
| Shrewsbury Business Improvement District Limited | Other services | 2014 |
| Shrewsbury Business Park Management Limited | Real estate | 1999 |
| Shrewsbury Car Parks Limited | Extraterritorial | 2008 |
| Shrewsbury Cars Ltd | Transport & logistics | 2023 |
| Shrewsbury Catering Equipment Limited | Manufacturing | 2003 |
| Shrewsbury Chiropody & Podiatry Limited | Health & social care | 2016 |
| Shrewsbury Chiropractic Clinic Ltd. | Health & social care | 2013 |
| Shrewsbury Civic Society Trust Limited | Other services | 1978 |
| Shrewsbury Cleaning Hub Limited | Administrative & support | 2019 |
| Shrewsbury Community Sauna CIC | Health & social care | 2026 |
| Shrewsbury CP Pizza Limited | Hospitality | 2026 |
| Shrewsbury CUP CIC | Wholesale & retail | 2019 |
| Shrewsbury Custom Computers Ltd | Information & communication | 2022 |
| Shrewsbury Dental Laboratory Ltd | Health & social care | 2004 |
| Shrewsbury Developments Limited | Construction | 2004 |
| Shrewsbury Direct Cremations Limited | Extraterritorial | 2024 |
| Shrewsbury Drain Services Limited | Water & waste | 2022 |
| Shrewsbury Drapers Holy Cross Limited | Hospitality | 2009 |
| Shrewsbury Drapers' Hall Preservation Trust | Administrative & support | 1998 |
| Shrewsbury Electrical Services (.Co.Uk) Ltd | Construction | 2014 |
| Shrewsbury Escapes Limited | Hospitality | 2024 |
| Shrewsbury Festivals Limited | Hospitality | 2016 |
| Shrewsbury Filipino Catering and Retail Services Ltd | Wholesale & retail | 2019 |
| Shrewsbury Fitting Centre Limited | Administrative & support | 2012 |
| Shrewsbury Folk Festival (UK) Limited | Arts & recreation | 2008 |
| Shrewsbury Food Ltd | Hospitality | 2026 |
| Shrewsbury Freemasons' Hall Company,Limited(The) | Other services | 1938 |
| Shrewsbury Garage Ltd | Wholesale & retail | 2017 |
| Shrewsbury Group of Anaesthetists Limited | Health & social care | 2020 |
| Shrewsbury Gymnastics Academy Limited | Arts & recreation | 2017 |
| Shrewsbury Hair Loss Clinic Limited | Other services | 2020 |
| Shrewsbury Half Marathon Ltd | Arts & recreation | 2019 |
| Shrewsbury Homes (Construction) Limited | Construction | 2008 |
| Shrewsbury Homes (Mill Court) Limited | Real estate | 2009 |
| Shrewsbury Homes (Mill Road) Limited | Construction | 2011 |
| Shrewsbury Homes (N1) Limited | Construction | 2014 |
| Shrewsbury Homes (R2) Ltd | Construction | 2025 |
| Shrewsbury Homes for ALL | Health & social care | 2011 |
| Shrewsbury Honda Centre Limited | Wholesale & retail | 1986 |
| Shrewsbury Joinery Limited | Manufacturing | 2012 |
| Shrewsbury Motors Ltd | Wholesale & retail | 2024 |
| Shrewsbury Osteopaths Limited | Health & social care | 2018 |
| Shrewsbury PCN Limited | Health & social care | 2023 |
| Shrewsbury Physiotherapy Limited | Health & social care | 2024 |
| Shrewsbury Pickleball Ltd | Arts & recreation | 2023 |
| Shrewsbury Pride CIC | Education | 2023 |
| Shrewsbury Property Investments 1. Ltd | Hospitality | 2020 |
| Shrewsbury Property Investments 2. Ltd | Professional & scientific | 2022 |
| Shrewsbury Railway Heritage Trust | Arts & recreation | 2003 |
| Shrewsbury Rowing Courses Limited | Arts & recreation | 2014 |
| Shrewsbury School Enterprises Limited | Administrative & support | 2002 |
| Shrewsbury School Trading Company Limited | Wholesale & retail | 2005 |
| Shrewsbury Slating & Tiling Limited | Construction | 1987 |
| Shrewsbury Sole Care Limited | Health & social care | 2003 |
| Shrewsbury ST Nicholas Boutique Hotel & Cafe Bar Ltd | Hospitality | 2017 |
| Shrewsbury Storage Limited | Real estate | 2010 |
| Shrewsbury Summer Season Ltd | Arts & recreation | 2011 |
| Shrewsbury Supermarket Market Ltd | Wholesale & retail | 2019 |
| Shrewsbury Sushi Ltd | Hospitality | 2024 |
| Shrewsbury Taxi Limited | Transport & logistics | 2026 |
| Shrewsbury Telecom Limited | Information & communication | 2007 |
| Shrewsbury Tourism Association Limited | Other services | 2002 |
| Shrewsbury Town Flooring Company Ltd | Construction | 2020 |
| Shrewsbury Town Football Club Foundation | Arts & recreation | 2008 |
| Shrewsbury Town Football Club Limited | Arts & recreation | 1936 |
| Shrewsbury Town Women's Football Club Ltd | Arts & recreation | 2023 |