| Ellisa Holdings Limited | Financial services | 2006 |
| ELM Shrewsbury Ltd | Real estate | 2022 |
| Elmer Arlyss Investments LLP | | 2020 |
| Elmer Arlyss Ltd | Construction | 2018 |
| Elson Construction (Shropshire) Ltd | Construction | 2019 |
| Elson Land Limited | Agriculture & fishing | 2014 |
| Elvan One Ltd | Real estate | 2026 |
| Embrace PE CIC | Education | 2025 |
| Embrace Physical Education Ltd | Education | 2013 |
| Embrey Property Services Ltd | Real estate | 2025 |
| Emcon Ltd | Professional & scientific | 2015 |
| Emdent Limited | Health & social care | 2010 |
| Emergency Protection Limited | Wholesale & retail | 2016 |
| Emivia Health Ltd | Health & social care | 2023 |
| Emlex Limited | Professional & scientific | 2014 |
| Emll Limited | Real estate | 2021 |
| Emma C Jones Ltd | Professional & scientific | 2021 |
| Emma Lawrence Designs Ltd | Arts & recreation | 2023 |
| Emma Wigley Mortgage Solutions Ltd | Financial services | 2015 |
| Emotion Office Limited | Wholesale & retail | 2020 |
| Empire Court Management (Havant) Limited | Households | 1994 |
| Employee Financial Wellbeing Solutions Ltd | Administrative & support | 2025 |
| Empower Cfsap CIC | Education | 2025 |
| Empower Trust | Education | 2018 |
| Empowering Sport Limited | Education | 2023 |
| Emstrey House NS Ltd | Real estate | 2018 |
| Emtec Laboratories Limited | Manufacturing | 2013 |
| Enbarr Horizons Ltd | Real estate | 2024 |
| Encountering Anti-Polonism Ltd | Professional & scientific | 2022 |
| Endcliffe Residents Company Limited | Households | 1987 |
| Endeavor Consultancy Limited | Information & communication | 2024 |
| Endless Escapes Ltd | Arts & recreation | 2025 |
| Endome Limited | Manufacturing | 2020 |
| Endorph Fitness Limited | Other services | 2021 |
| Endpoint Automation Services (EAS) UK Limited | Information & communication | 2024 |
| Endpoint Automation Services Group Limited | Financial services | 2023 |
| Energize Shropshire Telford and Wrekin | Arts & recreation | 2012 |
| Energy Equipment Limited | Construction | 2017 |
| ENG Construct Limited | Construction | 2021 |
| English (Group) Limited | Professional & scientific | 2010 |
| English Care Limited | Health & social care | 2004 |
| English Country Homes & Gardens Limited | Construction | 1998 |
| English Country Homes Limited | Professional & scientific | 1996 |
| English Developers Limited | Construction | 2002 |
| Enhance Coaching and Consultancy Ltd | Professional & scientific | 2016 |
| Enigma Kitchens & Bathrooms Limited | Manufacturing | 1997 |
| Enrikrauti Ltd | Professional & scientific | 2017 |
| Ensa Memorial Appeal | Other services | 2020 |
| Enterpoint Limited | Manufacturing | 1989 |
| Enterprise Prospects Ltd | Professional & scientific | 2009 |
| Entertaining Elephants Retail Limited | Wholesale & retail | 2022 |
| Env-Iro Cladding and Decks Ltd | Wholesale & retail | 2020 |
| Envida Limited | Water & waste | 2019 |
| Environment Analyst Limited | Information & communication | 2010 |
| Envolution Limited | Transport & logistics | 2007 |
| Enzo Connect Ltd | Construction | 2026 |
| EOS Learn Ltd | Education | 2019 |
| EPG Investments Limited | Real estate | 2022 |
| Epigraph Studio Ltd | Professional & scientific | 2025 |
| EPS Cleaning Services Ltd | Administrative & support | 2013 |
| EPS Printing Limited | Manufacturing | 2020 |
| Eps-Ts Ltd | Manufacturing | 2024 |
| Equals Outdoors Ltd | Education | 2026 |
| Equestrian EYE Ltd | Professional & scientific | 2021 |
| Equine Ventures Ltd | Agriculture & fishing | 2024 |
| Equinox (Cheltenham) Management Company Limited | Households | 2008 |
| Equiptec Limited | Manufacturing | 2018 |
| ER Developments Limited | Real estate | 2020 |
| Ercall Green Limited | Professional & scientific | 2024 |
| Ercall Hill Limited | Real estate | 2019 |
| Ernest Newton (Western) Limited | Extraterritorial | 1948 |
| Escapade Silverstone 38 Limited | Construction | 2024 |
| ESL Hire Ltd | Construction | 2019 |
| ESP Sales & Service Limited | Manufacturing | 2018 |
| Essential Driver Training Limited | Education | 2013 |
| Essential EAR Care Ltd | Health & social care | 2022 |
| Essential Energy Ltd | Construction | 2022 |
| Essential ID Solutions Limited | Financial services | 2007 |
| Essington Farm Limited | Wholesale & retail | 2010 |
| Essington Fruit Farm Limited | Extraterritorial | 2010 |
| Esther Holdings (Shropshire) Limited | Financial services | 2023 |
| ETJ Restore Therapy Limited | Other services | 2026 |
| Etonbrook Limited | Construction | 1985 |
| Europa Fastenings Limited | Manufacturing | 1995 |
| European Federation of Associations of Certification Bodies | Other services | 2002 |
| European Geophysical Services Limited | Professional & scientific | 1994 |
| European Transport Consultancy Limited | Transport & logistics | 2018 |
| Eurospace Resourcing Ltd | Administrative & support | 2010 |
| EVA Pizza Limited | Hospitality | 2024 |
| Evans & SON Funerals Ltd | Other services | 2024 |
| Evans Spraying Limited | Agriculture & fishing | 2022 |
| Evans Transport International Ltd | Transport & logistics | 2018 |
| Evansbowen (2010) Limited | Professional & scientific | 2010 |
| Evedale Care Limited | Health & social care | 2023 |
| Evelyn and MAY Ltd | Wholesale & retail | 2025 |
| Event Clip Limited | Manufacturing | 2012 |
| Eventide Communities Limited | Construction | 2008 |
| Evenwood Ltd | Professional & scientific | 2017 |
| Ever After Properties Ltd | Real estate | 2025 |
| Evercara Ltd | Financial services | 2025 |