| DAS HC Services Ltd | Health & social care | 2022 |
| Dash My WIG Limited | Hospitality | 2017 |
| Data and BI Limited | Information & communication | 2022 |
| Data Power Solutions Limited | Information & communication | 2009 |
| Datacrown Solutions Limited | Information & communication | 2002 |
| Datadream Ltd | Information & communication | 2020 |
| Datatag ID Limited | Wholesale & retail | 1987 |
| Davalex Care Ltd | Administrative & support | 2024 |
| Dave Linaker Plumbing & Heating Limited | Construction | 2008 |
| Dave Mellor Cycles Limited | Wholesale & retail | 2012 |
| Dave Morris Transport Ltd | Transport & logistics | 2010 |
| Dave Oliver Plumbing & Heating Limited | Construction | 2010 |
| Dave Rogers Investments Limited | Financial services | 2020 |
| David Barry Engineering Limited | Professional & scientific | 2012 |
| David Davies & Company LLP | | 2010 |
| David Davies Resources Ltd | Agriculture & fishing | 2010 |
| David Ellis Engineering Limited | Transport & logistics | 2011 |
| David Humphreys Limited | Professional & scientific | 2005 |
| David Jones Joinery Ltd | Construction | 2021 |
| David Jones Newtown Limited | Wholesale & retail | 2003 |
| David Potts Associates Limited | Professional & scientific | 2012 |
| David Reynolds Financial Services Limited | Financial services | 2012 |
| David Rogers Electrical Contractors Ltd | Manufacturing | 2001 |
| David Sutton Motortsport Limited | Wholesale & retail | 2019 |
| David Wood Painter & Decorator Limited | Construction | 2018 |
| Davies & Fisher Construction Ltd | Construction | 2008 |
| Davies & Fisher Property Ltd | Real estate | 2023 |
| Davies & Parry Ltd | Construction | 2006 |
| Davies Farms Ltd | Extraterritorial | 2019 |
| Davies Holiday Homes Limited | Hospitality | 2012 |
| Davies Homes & Leisure Ltd | Hospitality | 2021 |
| Davies Parry (Oakfields) Limited | Agriculture & fishing | 2015 |
| Davies Shaw Group Ltd | Extraterritorial | 2016 |
| Davies Shaw Limited | Manufacturing | 2016 |
| Day One Designs Ltd | Administrative & support | 2017 |
| Daytona Technologies Limited | Information & communication | 2013 |
| DB Innkeepers Limited | Real estate | 2014 |
| DBR Direct Ltd | Real estate | 2010 |
| DBS Golden Holdings Ltd | Administrative & support | 2023 |
| DC Solutions for YOU Limited | Other services | 2019 |
| DCE Research Ltd | Professional & scientific | 2018 |
| DCT & LAT Consulting Limited | Information & communication | 2011 |
| DDC Consulting Limited | Professional & scientific | 2009 |
| DE Beauvoir Management Limited | Households | 2021 |
| DE Havilland Homes Limited | Administrative & support | 2016 |
| DE Montfort (Phase 2) Management Company Limited | Households | 2004 |
| DE Montfort (Phase 4) Management Company Limited | Households | 2005 |
| DE Weijer Consulting Ltd | Professional & scientific | 2024 |
| Dealers Limited | Wholesale & retail | 1998 |
| Dean Price Equestrian Ltd | Agriculture & fishing | 2023 |
| Dean Rozier Ltd | Construction | 2003 |
| Deanman Properties Ltd | Real estate | 2019 |
| Deborah Udakis Consultancy Ltd | Professional & scientific | 2017 |
| Debra Nash Limited | Health & social care | 2013 |
| Decal Zone Limited | Manufacturing | 2025 |
| Decimal Work Limited | Administrative & support | 2022 |
| Decostitch Limited | Manufacturing | 2012 |
| Dedman Stores Ltd | Wholesale & retail | 2016 |
| Deep Keep Ltd | Information & communication | 2026 |
| Deep Progress Ltd | Professional & scientific | 2023 |
| Deerbourne Management Limited | Households | 2006 |
| Deers Leap (Phase 2) Management Company Limited | Households | 2011 |
| Defending the Motorist Ltd | Professional & scientific | 2011 |
| Deganwy Avenue (Llandudno) Management Limited | Households | 2007 |
| Deightonwood (2) Limited | Real estate | 2016 |
| Deightonwood Ltd | Real estate | 2014 |
| DEJ Management Ltd | Other services | 2017 |
| Deja-Vu Pre-Loved Limited | Wholesale & retail | 2024 |
| Delux Shape Ltd | Other services | 2022 |
| Demand Finder Limited | Information & communication | 2015 |
| Dennis Edwards Developments Limited | Construction | 2005 |
| Dennis Edwards Homes Ltd | Real estate | 2023 |
| Dennis Edwards Limited | Construction | 1999 |
| Denro Power Services Limited | Manufacturing | 2009 |
| Dent Mate Limited | Wholesale & retail | 2005 |
| Dental Monkey Ltd | Health & social care | 2019 |
| Dental Monkey WEM LLP | | 2006 |
| Dental Warehouse Ltd | Wholesale & retail | 2008 |
| Dentala Ltd | Administrative & support | 2010 |
| Dentflex Ltd | Professional & scientific | 2018 |
| Derby Care Home Living Limited | Health & social care | 2025 |
| Derek Griffiths Decorating Contractors Ltd | Construction | 2004 |
| Derek J Jones Fine Turf Machinery Ltd. | Manufacturing | 2014 |
| Dermaworks Ltd | Wholesale & retail | 2011 |
| Derwas Dale Farm Ltd | Agriculture & fishing | 2019 |
| Derwent Decorating Limited | Real estate | 1972 |
| Derwent Square Management Company Limited | Households | 2006 |
| Design by Country Limited | Professional & scientific | 2014 |
| Design Locations Limited | Administrative & support | 2010 |
| Designalife Limited | Administrative & support | 1999 |
| Designer Apartments (Ullett Road) Management Company Limited | Households | 2005 |
| Destiny Property Management Limited | Real estate | 2019 |
| Destis Ltd | Professional & scientific | 2019 |
| Detail-One Architecture Ltd. | Professional & scientific | 2017 |
| Development 31 Ltd | Construction | 2023 |
| Devey & Co. (Farms) Limited | Agriculture & fishing | 2026 |
| Devlin Dog Training Ltd | Other services | 2023 |
| Dexur Games Ltd | Information & communication | 2025 |
| Dfcmv Ltd | Financial services | 2025 |
| DFF Medics Limited | Health & social care | 2024 |