| Purely Pilates Hove Ltd | Arts & recreation | 2022 |
| Purfield Solutions Limited | Information & communication | 2002 |
| Purge Commercial Solutions Ltd | Water & waste | 2023 |
| Purple Computer Services Ltd | Information & communication | 2021 |
| Pyroban Group Limited | Professional & scientific | 1990 |
| Pyroban Limited | Manufacturing | 1978 |
| Q Cafe Limited | Hospitality | 2025 |
| QA Head Limited | Information & communication | 2024 |
| QL Homes Ltd | Real estate | 2014 |
| Qualita Global Ltd | Administrative & support | 2016 |
| Quality Matters Training and Consultancy Ltd | Education | 2011 |
| Qubicad Ltd | Information & communication | 2025 |
| Quintessential Decorating and Design Ltd | Construction | 2020 |
| R Knight Brickwork Limited | Construction | 2007 |
| R Remedy Ltd | Health & social care | 2006 |
| R2 Finance Limited | Financial services | 2014 |
| Race Nutrition Ltd | Wholesale & retail | 2011 |
| Rahian Limited | Wholesale & retail | 2024 |
| Rally Cars Livery Limited | Wholesale & retail | 2024 |
| Raydan Limited | Professional & scientific | 1990 |
| RDA Accountants (UK) Limited | Professional & scientific | 2022 |
| Re:Bourn Clothing Ltd | Wholesale & retail | 2024 |
| Realis Simulation Ltd | Information & communication | 2021 |
| Ream Creative Limited | Administrative & support | 2018 |
| Rebecca Hartley Educational Psychology Limited | Education | 2025 |
| Recruitment Software Consultancy Services Ltd | Information & communication | 2018 |
| Redash Group Limited | Other services | 2019 |
| Redlands Financial Planning Limited | Financial services | 2025 |
| Redwood Tree Publishing Ltd | Professional & scientific | 2015 |
| Reelmedia Film Ltd. | Information & communication | 2016 |
| Refurb and Construct Limited | Construction | 2024 |
| Regency Management Company Limited | Households | 1962 |
| Regiment Limited | Information & communication | 2025 |
| Regiment Music Publishing Limited | Information & communication | 2026 |
| Remoat Ltd | Information & communication | 2021 |
| Remote Visual Inspections Limited | Professional & scientific | 2003 |
| Resilient Intelligence Ltd | Information & communication | 2026 |
| Resilute Ltd | Professional & scientific | 2023 |
| Results of Kindness Ltd | Information & communication | 2023 |
| Retail Apprenticeship Partners Ltd | Professional & scientific | 2017 |
| Retail Exhibition Display Joinery Limited | Construction | 2004 |
| Revoco Saunas Limited | Health & social care | 2025 |
| Rexash Consultancy Limited | Other services | 2011 |
| Rhythm & Bikes Ltd | Other services | 2017 |
| Rhythm Retail Ltd | Hospitality | 2023 |
| RI Motors Ltd | Wholesale & retail | 2024 |
| Ricardo Asia Limited | Administrative & support | 1996 |
| Ricardo Certification Limited | Professional & scientific | 2015 |
| Ricardo Emea Limited | Professional & scientific | 2015 |
| Ricardo Innovations Limited | Financial services | 2014 |
| Ricardo Performance Products Limited | Manufacturing | 2023 |
| Ricardo Software Limited | Administrative & support | 2011 |
| Ricardo Strategic Consulting Limited | Manufacturing | 1999 |
| Ricardo UK Limited | Manufacturing | 1993 |
| Ricardo-Aea Limited | Information & communication | 2012 |
| Ricky Melville Consulting Ltd | Information & communication | 2026 |
| Rise Fire Safety Limited | Public administration | 2024 |
| Riverbeach (Shoreham) Limited | Households | 1971 |
| Riverside Reformer Ltd | Arts & recreation | 2025 |
| Rivervale Cars Limited | Wholesale & retail | 2003 |
| Rivervale Limited | Extraterritorial | 2003 |
| Rivervale Minibus Limited | Administrative & support | 1999 |
| Rivervale of Brighton Limited | Extraterritorial | 2007 |
| RJB Roofing&Construction Ltd | Construction | 2023 |
| Robal Freehold Ltd | Real estate | 2026 |
| Robal Properties Limited | Real estate | 2023 |
| Robal Studio Ltd. | Professional & scientific | 2018 |
| Robinson Gale-Tash UK Limited | Wholesale & retail | 2004 |
| Robinsons Scaffolding Ltd | Construction | 2025 |
| Roblewood Projects Ltd | Construction | 2024 |
| Rock Recruitment Ltd | Administrative & support | 2019 |
| Rocker FLY Ltd | Other services | 2013 |
| Roddick Morgan Ltd | Professional & scientific | 2026 |
| Rojava Mini Market Limited | Information & communication | 2019 |
| Roll Labels.Com Limited | Extraterritorial | 2016 |
| Ronski Limited | Real estate | 2012 |
| Roots Construction Ltd | Construction | 2018 |
| Roots Tutor Limited | Education | 2024 |
| Ropetackle Fish Ltd | Hospitality | 2025 |
| Ropetackle Ltd | Hospitality | 2010 |
| Ropetackle Management Company Limited | Households | 2004 |
| ROR Leisure Ltd | Arts & recreation | 2025 |
| Rosclare Residential Home Limited | Health & social care | 2005 |
| Rosco Infrastructure Limited | Construction | 2018 |
| ROX Electrical Ltd | Construction | 2017 |
| RP RTM Company Limited | Extraterritorial | 2024 |
| RPM Business Communications Limited | Administrative & support | 2014 |
| Rudycom Limited | Information & communication | 2014 |
| Run School Ltd | Extraterritorial | 2014 |
| Rushman and SON Holdings Limited | Financial services | 2023 |
| Russell House RTM Company Limited | Households | 2019 |
| Rust Studio Ltd | Professional & scientific | 2023 |
| Ruston Heights (Withdean Avenue) Residents Management Company Limited | Households | 2008 |
| Ruth Anslow Ltd. | Professional & scientific | 2013 |
| Rutland Scaffold Ltd | Construction | 2024 |
| Sabsound Limited | Information & communication | 2003 |
| SAF Consult Limited | Information & communication | 2012 |
| Sally Parkes Yoga Ltd | Health & social care | 2011 |
| Salty Dog Grooming Ltd | Other services | 2012 |
| Salvage Group Ltd | Construction | 2026 |