| Cr&Co Ltd | Professional & scientific | 2025 |
| CRA Consulting Limited | Administrative & support | 2012 |
| Crabtree Care Ltd | Health & social care | 2018 |
| Crabtree Limited | Households | 1984 |
| Cracked Media Ltd | Professional & scientific | 2021 |
| Cracked Reed Ltd | Information & communication | 2017 |
| Crackerjaw Limited | Information & communication | 2010 |
| Crackpots Ltd | Manufacturing | 2020 |
| Cradl Coffee Ltd. | Hospitality | 2025 |
| Craft Blanks Wholesale Limited | Wholesale & retail | 2020 |
| Craft Form Engineering Limited | Manufacturing | 2015 |
| Craft Haus Studio Ltd | Professional & scientific | 2024 |
| Craft Innkeeper Ltd | Information & communication | 2025 |
| Craft Legacy Ltd | Professional & scientific | 2024 |
| Craft of Photography Limited | Professional & scientific | 2024 |
| Craft Renewables Limited | Extraterritorial | 2014 |
| Craft Supplies Limited | Extraterritorial | 1997 |
| Crafted Elixir Limited | Manufacturing | 2023 |
| Crafted Syntax Limited | Information & communication | 2014 |
| Craftie - Charlie Limited | Wholesale & retail | 2011 |
| Crafts Wood Worx Ltd | Manufacturing | 2020 |
| Crafts YOU LOT Limited | Wholesale & retail | 2014 |
| Craftworks Micropub Ltd | Hospitality | 2019 |
| Crafty Devils Limited | Wholesale & retail | 2004 |
| Crafty FOX Market Limited | Professional & scientific | 2016 |
| Crafty Foxx Designs Ltd | Manufacturing | 2015 |
| Crafty MOO Ltd | Wholesale & retail | 2023 |
| Crafty Trading Limited | Wholesale & retail | 2012 |
| Craftyspottydog Limited | Extraterritorial | 2011 |
| Crag Digital Ltd | Professional & scientific | 2020 |
| Crag View Developments Ltd | Construction | 2025 |
| Cragg Ltd | Wholesale & retail | 2009 |
| Craig Richards Limited | Transport & logistics | 2017 |
| Craig Walker Haulage Ltd | Transport & logistics | 2023 |
| Crain Limited | Real estate | 2017 |
| Cramar Properties Limited | Real estate | 2019 |
| Crane & Hoist Limited | Professional & scientific | 2007 |
| Cranford Hall District Heating Ltd | Other services | 2014 |
| Cranmer Property Services Ltd | Real estate | 2024 |
| Cranswick Homes and Developments Ltd | Construction | 2021 |
| Cranworth Wharf & Transport Limited | Professional & scientific | 1946 |
| Crapper & Haigh Limited | Real estate | 2014 |
| Crater Law Solicitors Ltd | Professional & scientific | 2018 |
| Crave Communications Limited | Administrative & support | 2013 |
| Crawford Controls Limited | Manufacturing | 1997 |
| Crawler Cranes Limited | Wholesale & retail | 2003 |
| Craze Doctor Ltd | Wholesale & retail | 2020 |
| Crazy APE Competitions Ltd | Wholesale & retail | 2026 |
| CRB Home Improvements Ltd | Construction | 2023 |
| CRB Media Ltd | Information & communication | 2026 |
| CRC Trustee Limited | Extraterritorial | 2021 |
| CRD Hospitality Limited | Hospitality | 2016 |
| Creaghan & Sons Limited | Construction | 2013 |
| Create a Dream Foundation | Other services | 2016 |
| Create Acquisitions Ltd | Wholesale & retail | 2024 |
| Create Coffee Ltd | Hospitality | 2025 |
| Create Life Studio Ltd | Professional & scientific | 2025 |
| Create Partnerships Limited | Professional & scientific | 2020 |
| Create Sheffield | Education | 2018 |
| Create Spark Limited | Administrative & support | 2008 |
| Create Theatre School Limited | Arts & recreation | 2020 |
| Creation Staffing Services Ltd | Administrative & support | 2022 |
| Creative Admin Support Ltd | Professional & scientific | 2012 |
| Creative BI Partners Limited | Administrative & support | 2014 |
| Creative Brick Solutions Ltd | Information & communication | 2019 |
| Creative Building Projects Limited | Construction | 2014 |
| Creative Connections (Sheffield) C.I.C. | Arts & recreation | 2024 |
| Creative Elegance Limited | Wholesale & retail | 2013 |
| Creative House Services Ltd | Construction | 2023 |
| Creative Maintenance Ltd | Construction | 2025 |
| Creative Outdoor Spaces Ltd | Manufacturing | 2017 |
| Creative Restaurant (Berkeley) Limited | Hospitality | 2021 |
| Creative Space Management Limited | Real estate | 2005 |
| Creative Space Management Trustee Limited | Administrative & support | 2020 |
| Creative Stream Limited | Information & communication | 2006 |
| Creative Studio NC Ltd | Construction | 2019 |
| Creativezerouk CIC | Professional & scientific | 2021 |
| Creator 1991 Limited | Other services | 2012 |
| Creator Series Limited | Arts & recreation | 2025 |
| Creature Comforts Animal Boarding Limited | Agriculture & fishing | 2026 |
| Creche POD Limited | Real estate | 2011 |
| Credence Resources Ltd | Administrative & support | 2022 |
| Credence Traders and Suppliers Ltd | Wholesale & retail | 2026 |
| Credibility First Consultancy Ltd | Professional & scientific | 2015 |
| Credit Protection & Debt Recovery Agency Limited | Administrative & support | 2009 |
| Credit Style Holdings Limited | Professional & scientific | 2013 |
| Credit Style Limited | Financial services | 2007 |
| Creditmaster Ltd | Professional & scientific | 2009 |
| Creekside Properties Ltd | Real estate | 2025 |
| Cremsons Ltd | Financial services | 2025 |
| Creplocationhq Ltd | Wholesale & retail | 2025 |
| Cresair Limited | Real estate | 2009 |
| Crescens Consulting Ltd | Information & communication | 2010 |
| Crescent & Co Properties Ltd | Real estate | 2026 |
| Crescent Allure Care Services Limited | Health & social care | 2019 |
| Crescent Builders Limited | Construction | 2023 |
| Crescent Imaging Ltd | Health & social care | 2022 |
| Crescent Maintenance Limited | Households | 2006 |
| Crescent Property Solutions Limited | Real estate | 2023 |
| Cresko Ltd | Information & communication | 2025 |