| Zenon Limited | Arts & recreation | 2001 |
| Zensei Health Limited | Education | 2023 |
| Zentro Design Ltd | Professional & scientific | 2025 |
| Zenvio Ltd | Real estate | 2023 |
| Zenvyrox Ltd | Wholesale & retail | 2026 |
| Zeon Richards Consultancy Limited | Real estate | 2011 |
| Zephyr Medical Ltd | Health & social care | 2022 |
| Zeppin Concepts Ltd | Hospitality | 2023 |
| Zeqode Ltd | Wholesale & retail | 2025 |
| Zero Avenue Limited | Wholesale & retail | 2025 |
| Zero Binary Limited | Information & communication | 2020 |
| Zero Degrees S65 Limited | Hospitality | 2026 |
| Zero Threat Limited | Hospitality | 2022 |
| Zero Waste Works Limited | Construction | 2020 |
| Zeru Haile Ltd | Transport & logistics | 2020 |
| Zest Barbers Limited | Other services | 2024 |
| Zest Business Group Limited | Administrative & support | 2006 |
| Zest Cleaning Services Limited | Administrative & support | 2022 |
| Zest Fire Protection Ltd | Construction | 2023 |
| Zest Medical Limited | Administrative & support | 2010 |
| Zest Optical Limited | Administrative & support | 2007 |
| Zestbazaar Limited | Wholesale & retail | 2026 |
| Zestra Ltd | Health & social care | 2018 |
| Zete Solutions Limited | Wholesale & retail | 2025 |
| Zeticula Ltd | Information & communication | 2001 |
| Zeus Trucking Ltd | Transport & logistics | 2024 |
| Zewe Courier Services Ltd | Transport & logistics | 2026 |
| Zeylontra Travels Limited | Administrative & support | 2025 |
| Zeyn Tailoring Ltd | Manufacturing | 2021 |
| Zeze Limited | Wholesale & retail | 2023 |
| ZF Properties Ltd | Real estate | 2015 |
| Zforcel Jing Ltd | Manufacturing | 2023 |
| Zhang Anda Snooker Ltd | Arts & recreation | 2023 |
| Zhang's Trading Ltd | Wholesale & retail | 2014 |
| Zhao Xintong Snooker Ltd | Arts & recreation | 2021 |
| Zhaoyang Limited | Wholesale & retail | 2025 |
| Zharbat Limited | Hospitality | 2025 |
| Zhong Bang Business Limited | Transport & logistics | 2017 |
| Zhong Jing TCM UK Ltd | Professional & scientific | 2016 |
| Zhong Xing Group Limited | Wholesale & retail | 2025 |
| Zhou Yuelong Snooker Limited | Arts & recreation | 2018 |
| Zhuoren Zhai Limited | Other services | 2013 |
| ZHY Evergreen Limited | Wholesale & retail | 2025 |
| Zicman Properties Limited | Real estate | 2020 |
| Zidane Outlet Ltd | Wholesale & retail | 2025 |
| Zidicat Ltd | Information & communication | 2017 |
| Zilan Food Limited | Wholesale & retail | 2023 |
| Zilanroj International Food Ltd | Wholesale & retail | 2025 |
| Zilio Ltd | Professional & scientific | 2023 |
| Zillasstudio Ltd | Information & communication | 2025 |
| Zina Market Limited | Wholesale & retail | 2023 |
| Zina Super CUT Saloon Limited | Other services | 2023 |
| Zint Technology Limited | Information & communication | 2018 |
| Zion Hall Ltd | Hospitality | 2026 |
| Zion Premium Limited | Administrative & support | 2019 |
| ZIP Screens Limited | Extraterritorial | 1993 |
| Ziporah Services Ltd | Health & social care | 2018 |
| Zippy Munch Ltd | Hospitality | 2025 |
| Zita Steel Cleaners Ltd | Administrative & support | 2026 |
| Zitamar Ltd | Information & communication | 2015 |
| Zizas Shop Limited | Wholesale & retail | 2025 |
| Zizu Housing Limited | Real estate | 2024 |
| Zizu Ventures Limited | Real estate | 2026 |
| ZJB Transport Limited | Transport & logistics | 2025 |
| ZJH UK Ltd | Real estate | 2018 |
| ZK Enterprise Consultants Ltd | Wholesale & retail | 2014 |
| ZLN Building Services Ltd | Construction | 2016 |
| ZMB Joinery Ltd | Construction | 2026 |
| ZMB Legal Ltd | Professional & scientific | 2025 |
| Zmrk Holdings Ltd | Financial services | 2024 |
| ZMT (UK) Limited | Administrative & support | 2013 |
| ZOD Property & Investment Limited | Real estate | 2026 |
| ZOE Flower Ltd | Information & communication | 2018 |
| Zoe&Sam Limited | Real estate | 2020 |
| Zoe's Kitchen Ltd | Hospitality | 2011 |
| Zoe's Kitchen Takeaway Ltd | Hospitality | 2024 |
| Zoefave Ltd | Health & social care | 2022 |
| Zoeylight Limited | Wholesale & retail | 2026 |
| Zolde Ltd | Professional & scientific | 2023 |
| Zone Business Solutions Limited | Information & communication | 2009 |
| Zone Group Holdings Limited | Professional & scientific | 2017 |
| Zonecyber Limited | Information & communication | 2026 |
| Zonegreen Limited | Information & communication | 1984 |
| Zones (Sheffield) Ltd | Hospitality | 2024 |
| Zonnix UK Limited | Wholesale & retail | 2011 |
| ZOO Digital Group PLC | Information & communication | 1999 |
| ZOO Digital Limited | Information & communication | 2001 |
| ZOO Digital Production Limited | Extraterritorial | 2000 |
| ZOO Employee Share Trust Limited | Professional & scientific | 2000 |
| ZOO Shop Limited | Wholesale & retail | 2018 |
| ZOO V2 Ltd | Wholesale & retail | 2026 |
| Zoom Funding Limited | Financial services | 2018 |
| Zoomic UK Ltd | Wholesale & retail | 2025 |
| Zoomphysio Ltd | Wholesale & retail | 2021 |
| Zoon Ltd | Wholesale & retail | 2026 |
| Zoopraxiphone Limited | Information & communication | 2011 |
| Zootech Limited | Professional & scientific | 1999 |
| Zopf PR Limited | Professional & scientific | 2016 |
| Zorbas Swallownest Limited | Hospitality | 2023 |
| Zorock Introserves (UK) Ltd | Administrative & support | 2016 |