| Supreme Body Work Ltd | Wholesale & retail | 2020 |
| Supreme Global Trading Ltd | Hospitality | 2026 |
| Supreme Ice Cream Limited | Extraterritorial | 2010 |
| Supreme Loss Prevention Limited | Construction | 2021 |
| Supreme Nails 360 Ltd | Other services | 2025 |
| Supreme Origins Limited | Education | 2018 |
| Supreme Suites Ltd | Real estate | 2024 |
| Surafi Ltd | Real estate | 2026 |
| Sure Tech Services Ltd | Information & communication | 2020 |
| Sure Technologies Limited | Information & communication | 2014 |
| SURE2B Limited | Real estate | 2016 |
| Surebay Properties Limited | Construction | 2005 |
| Surefix Direct Limited | Construction | 2003 |
| Surefix Solutions Limited | Construction | 2019 |
| Sureguard Energy Services Limited | Other services | 1983 |
| Surelight Ltd | Manufacturing | 2015 |
| Surelok Limited | Manufacturing | 2020 |
| Surely Music Limited | Professional & scientific | 2022 |
| Suretek ETS Limited | Professional & scientific | 2009 |
| Surf Financials Ltd | Extraterritorial | 2025 |
| Surface Finishing Equipment Group Limited | Manufacturing | 2009 |
| Surface Planning Limited | Professional & scientific | 2019 |
| Surface Preparation UK Holdings Limited | Financial services | 2021 |
| Surfaceprep UK Limited | Financial services | 2021 |
| Surge Films CIC | Information & communication | 2026 |
| Surgimed Clinic Limited | Health & social care | 2010 |
| Surgipack Limited | Other services | 2013 |
| Suron Medical Care Ltd | Health & social care | 2022 |
| Survive, Strive, Thrive Ltd | Education | 2021 |
| Susan Cottrill & Co Limited | Professional & scientific | 2011 |
| Susan Hunter Consultancy Limited | Administrative & support | 1999 |
| Susan Mchale Properties Ltd | Real estate | 2025 |
| Susan Smith Limited | Professional & scientific | 2005 |
| Sushisushi Limited | Wholesale & retail | 2011 |
| Suspension Supplies Limited | Wholesale & retail | 2016 |
| Suspicious Minds Ltd | Wholesale & retail | 2007 |
| Sustainability Made Simple CIC | Professional & scientific | 2025 |
| Sustainability Support Service Ltd | Information & communication | 2020 |
| Sustainable Balance Limited | Professional & scientific | 2012 |
| Sustainable Green IT Ltd | Other services | 2023 |
| Sustainable Shell Homes Limited | Construction | 2019 |
| Sustainablefarm Innovations Ltd | Agriculture & fishing | 2023 |
| Suthan Medical Limited | Health & social care | 2014 |
| Sutherland Farms (Holdings) Limited | Agriculture & fishing | 2011 |
| Sutton Mcgrath Hartley (Financial Services) LLP | | 2014 |
| Sutton Mcgrath Hartley (Rotherham) Limited | Extraterritorial | 2013 |
| Sutton Mcgrath Hartley Ltd | Professional & scientific | 1995 |
| Sutton Mcgrath Hartley Wath Upon Dearne Ltd | Extraterritorial | 2013 |
| Suvipharma Ltd | Wholesale & retail | 2021 |
| Suzanna Anthony Therapy Limited | Administrative & support | 2015 |
| Suzanne Bryant IT Delivery Management Limited | Information & communication | 2023 |
| Suzerain Homes Limited | Real estate | 2020 |
| Suzie's Deeds Cleaners Limited | Administrative & support | 2016 |
| Suzuki Drifting Ltd | Arts & recreation | 2023 |
| Sverdrup Steel UK Limited | Wholesale & retail | 2012 |
| SVL Trading Limited | Transport & logistics | 2016 |
| SVN Development Holdings Ltd | Real estate | 2024 |
| SVS Multimedia Limited | Other services | 2009 |
| SVW Consulting Limited | Information & communication | 2012 |
| SW Centre Property Limited | Wholesale & retail | 2001 |
| SW Electrical Works Ltd | Construction | 2025 |
| SW Motors and SON Ltd | Wholesale & retail | 2022 |
| SW Total Management Limited | Professional & scientific | 2018 |
| SW Trading Limited | Professional & scientific | 2026 |
| SW500 Films Limited | Information & communication | 2016 |
| Swag Creative Ltd | Wholesale & retail | 2018 |
| Swain Build Ltd | Construction | 2025 |
| Swallow (GB) Limited | Manufacturing | 2009 |
| Swallow Financial Management LLP | | 2002 |
| Swallowbeck Ltd | Information & communication | 2023 |
| Swallownest & Airport Taxis Limited | Transport & logistics | 2001 |
| Swallownest Health Care Limited | Health & social care | 2006 |
| Swallownest Miners' Welfare Social Club Limited | Hospitality | 2002 |
| Swallownest Sun Rooms Ltd | Other services | 2025 |
| Swallows and Damsons Limited | Wholesale & retail | 2008 |
| SWAMP81 Limited | Information & communication | 2013 |
| Swana Engineering Solutions Limited | Professional & scientific | 2022 |
| Swanbury-Laine Developments (Northern) Limited | | 1981 |
| Swann-Morton (Europe) Limited | Manufacturing | 1990 |
| Swann-Morton (Services) Ltd. | Professional & scientific | 1948 |
| Swann-Morton Laboratory Services Limited | Professional & scientific | 2000 |
| Swann-Morton Limited | Manufacturing | 1961 |
| Swanneck Trading Co Ltd | Wholesale & retail | 2026 |
| Swanson Property Ltd | Real estate | 2026 |
| Swanston Consultancy Ltd | Professional & scientific | 2023 |
| Swastik Group Limited | Hospitality | 2024 |
| Swat Private Limited | Health & social care | 2019 |
| SWB Steel Services (Holdings) Limited | Professional & scientific | 1982 |
| SWB Steel Services Limited | Wholesale & retail | 2002 |
| SWB Testing Ltd | Professional & scientific | 2015 |
| Swedish Dads UK Limited | Information & communication | 2026 |
| Swedish Rugs & Runners Limited | Wholesale & retail | 2024 |
| Swedisons Ltd | Water & waste | 2023 |
| Sweeny 5 Ltd | Other services | 2020 |
| Sweepforward Cleaning Services Ltd | Administrative & support | 2019 |
| Sweet 'N' Greet Ltd | Wholesale & retail | 2023 |
| Sweet Adeline Ltd. | Manufacturing | 2018 |
| Sweet Dreams of Otherness Ltd | Professional & scientific | 2023 |
| Sweet House Cafe Ltd | Hospitality | 2019 |
| Sweet Irene Limited | Arts & recreation | 2021 |