| Sophos Systems Ltd | Information & communication | 2024 |
| Sorbus Services Ltd | Professional & scientific | 2021 |
| South East Beach Limited | Administrative & support | 2025 |
| Spell Beautiful Limited | Health & social care | 2018 |
| Sports CUT Ltd | Other services | 2026 |
| Stone Crabs Productions | Arts & recreation | 2003 |
| Store IT (IOW) Ltd | Transport & logistics | 2006 |
| Student Habitat Ltd | Real estate | 2024 |
| Sturrock Homes Ltd | Real estate | 2024 |
| Style Lounge Ltd | Other services | 2024 |
| Sun Rise Hotel Ltd | Hospitality | 2025 |
| Sunrise Hospitalities Ltd | Hospitality | 2026 |
| SW Country Homes Ltd | Real estate | 2025 |
| SW2025 Limited | Real estate | 2025 |
| Tamora Meat Company Ltd | Wholesale & retail | 2018 |
| Taylors of Wight Ltd | Construction | 2025 |
| Thai Mukda Shanklin Limited | Hospitality | 2019 |
| THE Burrow Isle of Wight CIC | Wholesale & retail | 2026 |
| THE Cambria Management Limited | Households | 2005 |
| THE Colonnades Westhill Manor Management Company Limited | Administrative & support | 2006 |
| THE Crossley Company (IOW) Ltd | Education | 2010 |
| THE Falcon PUB Shanklin Ltd | Hospitality | 2010 |
| THE Havelock (Isle of Wight) Ltd | Hospitality | 2019 |
| THE Hollies (Sandown) Management Limited | Households | 2004 |
| THE Home and Textile Limited | Wholesale & retail | 2015 |
| THE Littlest Footprint Limited | Manufacturing | 2013 |
| THE Mortgage Matcher Ltd | Financial services | 2020 |
| THE Old Thatch LLP | | 2008 |
| THE Q Boutique Hotel Ltd | Hospitality | 2023 |
| THE Resource Exchange Limited | Information & communication | 2003 |
| THE Rock Shop LLP | | 2008 |
| THE Shanklin Chine Trust | Arts & recreation | 1997 |
| THE TAP PUB Sandown Ltd | Hospitality | 2025 |
| THE Whanau Project Limited | Hospitality | 2021 |
| THE Wighthill Ltd | Hospitality | 2026 |
| Thread and Tote Ltd | Wholesale & retail | 2025 |
| Three Gates Limited | Transport & logistics | 2021 |
| Toneworks Ltd | Professional & scientific | 2025 |
| Touchstone Resources Limited | Wholesale & retail | 1996 |
| Tradewinds Cafe Limited | Hospitality | 2015 |
| Trident Marine Systems and Services Limited | Manufacturing | 2020 |
| Undercliff Accounting Ltd | Professional & scientific | 2016 |
| Upper Chine (Shanklin) Management Limited | Households | 2018 |
| Valemont Limited | Arts & recreation | 2011 |
| Vectis Healthcare Solutions Ltd | Professional & scientific | 2021 |
| Vectis Technology Ltd | Information & communication | 2025 |
| Vibes Events Management Ltd | Hospitality | 2020 |
| Villanelle Heritage Limited | Real estate | 2024 |
| Voltpol Electrical Services Ltd | Construction | 2025 |
| W.I.S.C Isle of Wight Ltd | Hospitality | 2019 |
| W.J.Nigh & Sons Limited | Wholesale & retail | 1938 |
| WA Foods Limited | Hospitality | 2018 |
| Walton Lodge Residents Association Limited | Households | 1996 |
| Watermen Foods Limited | Wholesale & retail | 2005 |
| White Petals Ltd | Wholesale & retail | 2015 |
| Wight Coastal Plumbing Limited | Construction | 2025 |
| Wight Developments (IW) Limited | Construction | 2005 |
| Wight Electromagnetics Limited | Manufacturing | 1996 |
| Wight Host Partners Ltd | Real estate | 2026 |
| Wight Hotel Management Limited | Administrative & support | 2011 |
| Wight Hotels Limited | Hospitality | 2019 |
| Wight Model Railway Group | Arts & recreation | 2006 |
| Wight Property Partners LLP | | 2021 |
| Wight Sound Hearing Limited | Health & social care | 2000 |
| Wight Spark Electrical Limited | Construction | 2025 |
| Wightgold Properties Ltd | Households | 2026 |
| Wighthill Bungalows Ltd | Hospitality | 2026 |
| Willow Brook Touring Park LLP | | 2012 |
| Winford Farm Fisheries Limited | Agriculture & fishing | 2022 |
| Woods Architects Ltd | Professional & scientific | 2026 |
| Woods Group IOW Limited | Financial services | 2026 |
| Workshop 25 Limited | Real estate | 2026 |
| Worsley View Management Company Limited | Households | 2018 |
| Wunderbär Holdings Limited | Professional & scientific | 2024 |
| Wykes Blade Repair IOW Ltd | Manufacturing | 2026 |
| Wykes IOW Ltd | Real estate | 2026 |
| Yanuka Ltd | Financial services | 2020 |
| YB Consultancy Limited | Administrative & support | 2015 |
| Zapline Electrical Ltd | Construction | 2026 |