| Deli-Weli Ltd | Wholesale & retail | 2018 |
| Devon Appliances Ltd | Wholesale & retail | 2013 |
| Devon Asset Management Ltd | Financial services | 2021 |
| Devon Developments Ltd | Financial services | 2018 |
| Devon EEL Company Ltd | Wholesale & retail | 2018 |
| Devon Joinery Ltd. | Manufacturing | 2009 |
| DFM Film Limited | Information & communication | 2022 |
| DH Drivers Ltd | Extraterritorial | 2020 |
| DH Team Ltd | Administrative & support | 2017 |
| Digital Eyes Consulting Ltd | Professional & scientific | 2023 |
| Dinosaur Cleaning Ltd | Administrative & support | 2026 |
| Disha Fish Bar Ltd | Hospitality | 2023 |
| Disha Food Services Ltd | Hospitality | 2025 |
| Doctor Mind Ltd | Health & social care | 2023 |
| Doid Ltd. | Information & communication | 1998 |
| Dolly TOO Ltd | Wholesale & retail | 2022 |
| Dorchester Court RTM Company Limited | Households | 2009 |
| Dorset and Devon Holiday Cottages Limited | Administrative & support | 2025 |
| DR Birgit Vote Psychology Ltd | Health & social care | 2022 |
| DR Chloe Walker Ltd | Health & social care | 2023 |
| DR Christina Ltd | Health & social care | 2021 |
| DR Danielle Crane Ltd | Health & social care | 2024 |
| DR Jasmin Aquan-Assee Ltd | Professional & scientific | 2023 |
| DR Jayne Griffiths Psychology Ltd | Health & social care | 2025 |
| DR Jessica Jackson Clinical Neuropsychology Limited | Health & social care | 2020 |
| DR Jessica Townsend Psychology Ltd | Health & social care | 2023 |
| DR JO the Psychologist Ltd | Health & social care | 2024 |
| DR Lana Jackson Ltd | Health & social care | 2024 |
| DR Rebecca Moran Psychology Services Limited | Health & social care | 2024 |
| DR Rosie Burton Psychology Ltd | Health & social care | 2021 |
| Dragoneye Digital Limited | Information & communication | 2023 |
| Dragoneye Limited | Administrative & support | 2016 |
| Dreamtown Entertainment Limited | Information & communication | 2023 |
| Dreamtown Film Limited | Information & communication | 2024 |
| Ducky's (Beer) Limited | Hospitality | 2003 |
| Dulwichminds Ltd | Health & social care | 2024 |
| Dungoyne Limited | Administrative & support | 2021 |
| Dunkeswell Holdings Ltd | Real estate | 2018 |
| E.K Trading Limited | Administrative & support | 2016 |
| Eagle Road Flats RTM Company Limited | Households | 2015 |
| East Devon Coastal Properties Ltd | Real estate | 2022 |
| East Devon Physiotherapy Ltd. | Health & social care | 2006 |
| East Devon Soul CIC | Arts & recreation | 2025 |
| East Devon Windows Limited | Manufacturing | 2022 |
| Eastlea Gardens Management Company | Households | 2020 |
| Edgelands Film Limited | Information & communication | 2026 |
| Electra Star Dance Limited | Education | 2019 |
| Electroplumb Ltd | Construction | 2025 |
| Elevate Psychology Services Ltd | Health & social care | 2024 |
| Eleven the Cliff (Brighton) Limited | Households | 2004 |
| Elize Enterprise Ltd | Wholesale & retail | 2016 |
| Emm-Lec Construction Limited | Financial services | 2011 |
| Emm-Lec Limited | Construction | 2002 |
| ENGEN3 Limited | Information & communication | 2026 |
| Erimus Chambers Limited | Professional & scientific | 2014 |
| Esmould Property Services Ltd | Real estate | 2026 |
| Esprit Property Ltd | Real estate | 2016 |
| Est-E-Mate (South West) Ltd | Construction | 2014 |
| Eusa Distributors Ltd | Wholesale & retail | 2012 |
| Evariane Ltd | Professional & scientific | 2026 |
| Exoracing Ltd | Wholesale & retail | 2018 |
| Extractive Projects Limited | Professional & scientific | 2011 |
| FACE2FACE Consulting Limited | Professional & scientific | 2026 |
| Farringtons Commercials Ltd | Wholesale & retail | 2015 |
| Fathom Court RTM Company Ltd | Households | 2015 |
| FD Perspective Limited | Professional & scientific | 2019 |
| Feast (Lyme Bay) Ltd | Hospitality | 2020 |
| Fenetts Investments Ltd | Real estate | 2020 |
| Fieldstone Architecture Ltd | Professional & scientific | 2019 |
| Fifi & Binx Ltd | Wholesale & retail | 2021 |
| Flat 11 Fairlawn House Limited | Real estate | 2021 |
| Fleet Court (Seaton) Limited | Real estate | 2005 |
| Flex Eco Services Ltd | Construction | 2017 |
| Foley's 4C'S Limited | Hospitality | 2007 |
| Force TEN Survey Ltd | Construction | 2019 |
| Forest Path Property Ltd | Real estate | 2025 |
| Fortnam Smith & Banwell (Lyme Regis) Limited | Real estate | 2006 |
| Four Paws Therapy Ltd | Manufacturing | 2018 |
| Frippadviser Limited | Financial services | 2017 |
| Frydays (SW) Ltd. | Hospitality | 2009 |
| FSB Lyme Regis Ltd | Extraterritorial | 2024 |
| FSB Rentals Limited | Real estate | 2017 |
| FSB Seaton Ltd | Real estate | 2016 |
| Fulton House Management Limited | Households | 1987 |
| Fusion Trade Collective Ltd | Professional & scientific | 2024 |
| G Sims (Devon) Ltd | Hospitality | 2012 |
| Garden Wright Limited | Extraterritorial | 2015 |
| Garlands Boat Shed Ltd | Real estate | 2023 |
| Garlands Cottages Ltd | Real estate | 2022 |
| Gate House (49-51 High Street) RTM Company Limited | Households | 2025 |
| Gate House (Goosecroft Lane) RTM Company Limited | Households | 2025 |
| Gayle Hocking Health Limited | Health & social care | 2025 |
| Gella Collective Limited | Wholesale & retail | 2025 |
| Georgie King Interiors Ltd | Professional & scientific | 2023 |
| GES (SW) Ltd | Construction | 2016 |
| Glebe Farm Holdings Ltd | Agriculture & fishing | 2020 |
| Glenholme Consulting Ltd | Professional & scientific | 2011 |
| Gloucester Gate (Basildon) Management Company Limited | Households | 2014 |
| Golden CAP Property Ltd | Real estate | 2023 |
| Goldfinch International Limited | Information & communication | 2023 |