| Bawse and Co Ltd | Hospitality | 2025 |
| Beacon Surveying Limited | Professional & scientific | 2024 |
| Beaufort Place (Crawley) Management Company Limited | Households | 2016 |
| Beecroft Communications Consultancy Ltd | Information & communication | 2014 |
| BEN 9 Limited | Information & communication | 2002 |
| Bena Corp Limited | Professional & scientific | 2024 |
| Bewick Court (RYE) Management Company Limited | Households | 2015 |
| Bewiser Solutions Ltd | Information & communication | 2025 |
| Bexonet Limited | Information & communication | 2012 |
| Biker Bits Ltd | Wholesale & retail | 2013 |
| Bill Edmeads Roofing Contractors Ltd | Construction | 2020 |
| Black Label Financial Ltd | Financial services | 2010 |
| Blackbarn Foods Limited | Hospitality | 2014 |
| Blackgate Security Ltd | Administrative & support | 2024 |
| Blatchington Hill Flats (Seaford) Limited | Households | 2020 |
| Block Guitar Limited | Wholesale & retail | 2020 |
| Blok Products Ltd | Manufacturing | 2018 |
| Blonde and Beyond Ltd | Other services | 2025 |
| Blue and Green Properties and Investments Limited | Real estate | 2018 |
| Blue Spot Property Limited | Real estate | 2007 |
| Blue Squared LLP | | 2010 |
| BM Event Productions Ltd | Administrative & support | 2025 |
| BN Shutters Ltd | Wholesale & retail | 2023 |
| BN1 Brighton Consulting Limited | Professional & scientific | 2016 |
| BON BON Jewellery Club Ltd | Wholesale & retail | 2021 |
| Branchwalkers Group Ltd | Agriculture & fishing | 2018 |
| Breakaway Agency Europe Ltd | Education | 2021 |
| Brighton Gutter Cleaning Ltd | Administrative & support | 2014 |
| BRIGHTON3D Ltd | Information & communication | 2023 |
| British Athletics Coaches Association Ltd | Education | 2022 |
| Bryans Property Holdings Limited | Real estate | 2017 |
| Built for Mars Ltd | Information & communication | 2020 |
| Burfield & Sons Ltd. | Manufacturing | 2016 |
| Buywize Drinks Ltd | Wholesale & retail | 2016 |
| Byeways Road Management Company Limited | Real estate | 2007 |
| C J Self Limited | Health & social care | 2003 |
| C&G Education Ltd | Education | 2022 |
| C&S Teamwear Limited | Wholesale & retail | 2018 |
| C2V Ltd | Professional & scientific | 2025 |
| Caburn Construction Ltd | Construction | 2019 |
| Caffe POD Ltd | Manufacturing | 2023 |
| Canelle Design Limited | Other services | 2012 |
| Caredata Ltd | Real estate | 2023 |
| Carers Support and Wellbeing CIC | Health & social care | 2021 |
| Carew Views Management Limited | Households | 1986 |
| Carwent Limited | Households | 2001 |
| Castle Hill Consulting Ltd | Professional & scientific | 2019 |
| Caterham Interiors Ltd | Manufacturing | 2008 |
| Catmando Boarding Cattery Limited | Hospitality | 2014 |
| CEE Surveys Limited | Professional & scientific | 2008 |
| Celllife U.K. Limited | Manufacturing | 1978 |
| Cheeky Baby Products Limited | Wholesale & retail | 2011 |
| Cherrypicker Roofing & Access Hire Southern Ltd | Construction | 2026 |
| Chichester Court (Seaford) Limited | Professional & scientific | 1997 |
| Chittenden Holdings Limited | Real estate | 2015 |
| Chrysalis Construction & Project Management Ltd | Construction | 2010 |
| Chyngton Court (Seaford) Limited | Households | 1960 |
| Chyngton Management Services Limited | Professional & scientific | 2015 |
| Cinque Ports Seaford Limited | Hospitality | 2024 |
| Cityside Events Limited | Arts & recreation | 2023 |
| Cjot Sussex Limited | Financial services | 2024 |
| Clanlu Investments Limited | Administrative & support | 2006 |
| Classic Cars of Kent Limited | Manufacturing | 1997 |
| Classic Property Management Ltd | Real estate | 2017 |
| Clearview Court Ltd | Real estate | 2007 |
| CMB Equine Dentistry Ltd | Professional & scientific | 2026 |
| Coastside Homes Limited | Construction | 2008 |
| Colleary Group Limited | Financial services | 2019 |
| Combro Limited | Manufacturing | 2006 |
| Community Basketball Academy CIC | Education | 2026 |
| Community Basketball Initiative CIC | Education | 2019 |
| Community Health Collective CIC | Health & social care | 2026 |
| Connaught House Seaford Limited | Real estate | 1962 |
| Consider Yourself CIC | Hospitality | 2022 |
| Copcraft Limited | Education | 2026 |
| Coplestone Tree Surgery Limited | Administrative & support | 2015 |
| Core Accounting Services Ltd | Professional & scientific | 2011 |
| Cornerstone Management Limited | Real estate | 2025 |
| Cornhill Finance & Management Limited | Real estate | 2013 |
| Cosmo Construction (UK) Ltd | Construction | 2013 |
| Countywide Driving School Ltd | Other services | 1998 |
| Crabtree House Residents Association Limited | Hospitality | 1988 |
| Craftsman Press Limited | Real estate | 1958 |
| Crawford Carpets Limited | Wholesale & retail | 1990 |
| Crawley Jennion Holdings Limited | Financial services | 2021 |
| Creating the Edge Limited | Other services | 2016 |
| Creative Buzz Media Limited | Information & communication | 2013 |
| Creative Mortgage Solutions Limited | Financial services | 2024 |
| Creativity Takes Courage Ltd | Arts & recreation | 2019 |
| CREW4 North Limited | Manufacturing | 2017 |
| Crowhurst Marketing Collective Ltd | Professional & scientific | 2026 |
| Croxford Close Management Company Limited | Households | 2018 |
| Cruise FX Ltd | Information & communication | 2024 |
| Crusade Consulting Limited | Professional & scientific | 2020 |
| Crusoe Care Limited | Health & social care | 2009 |
| Cside Flyers Limited | Professional & scientific | 2005 |
| Cuckmere Building Design Ltd | Professional & scientific | 2023 |
| Cuckmere Court Residents Association Limited | Households | 1998 |
| Curl Carpentry Ltd | Construction | 2026 |
| Dalgain Biomedical Ltd | Professional & scientific | 2021 |