| Edwards Automotive South West Ltd | Wholesale & retail | 2020 |
| Efficiency Wise Ltd | Professional & scientific | 2026 |
| Effordless Ltd | Wholesale & retail | 2016 |
| Egkr Ltd | Wholesale & retail | 2020 |
| Electricair SW Ltd | Manufacturing | 2025 |
| Elegant Floors Limited | Wholesale & retail | 2013 |
| Elephant House Productions Ltd | Professional & scientific | 2025 |
| Ellenden Homes Ltd | Real estate | 2025 |
| Ellenden Limited | Real estate | 2006 |
| Embetel Limited | Information & communication | 2006 |
| Enchanted Day Nursery Hooe Holding Ltd | Financial services | 2026 |
| Enchanted Day Nursery Hooe Ltd | Education | 2026 |
| Entyre Supplies Ltd | Extraterritorial | 2023 |
| Envy Hair Design Limited | Other services | 2003 |
| EPF Boiler Breakdowns Ltd | Other services | 2019 |
| Ephesus Shipping Ltd | Transport & logistics | 2017 |
| Eric Doel Quality Inspections Limited | Professional & scientific | 2020 |
| ERP Onprem Limited | Information & communication | 2020 |
| Essa Architects LLP | | 2026 |
| Essa Building Solutions Ltd | Construction | 2023 |
| Essa Estates Limited | Real estate | 1973 |
| Essa PRM Limited | Real estate | 2017 |
| Essaedge Ltd | Wholesale & retail | 2025 |
| Essential Services S.W. Ltd | Construction | 2018 |
| Ethan Bargains Limited | Wholesale & retail | 2026 |
| Ethanwalshmusic Ltd | Information & communication | 2025 |
| Ethical Investments (SW) Ltd | Financial services | 2018 |
| Euro Tactical Ltd | Wholesale & retail | 2006 |
| Evans Oak Limited | Construction | 2025 |
| Excel Plymouth Ltd | Professional & scientific | 2015 |
| Excelsa Floors Ltd | Construction | 2023 |
| Exterior Cleaning Supplies UK Limited | Wholesale & retail | 2024 |
| Extreme Property Solutions Limited | Administrative & support | 2023 |
| F W Rogers Garage (Saltash) Limited | Wholesale & retail | 1978 |
| Face & Field BDS Ltd | Health & social care | 2024 |
| Face & Field Wealth Management Ltd | Real estate | 2024 |
| Facility Review Ltd | Financial services | 2016 |
| Falic (South West) Limited | Real estate | 2007 |
| Famas Geosolutions Community Interest Company | Professional & scientific | 2025 |
| Faro Holdings Ltd | Financial services | 2024 |
| FD Builders Limited | Construction | 2013 |
| Field Fresh (SW) Limited | Wholesale & retail | 2017 |
| Financial Lifestyling Limited | Financial services | 2011 |
| Find Care Compare Ltd | Information & communication | 2024 |
| Firstpay Technology Limited | Manufacturing | 2026 |
| FLATSEAL20 Limited | Construction | 2008 |
| Focused Vision Limited | Professional & scientific | 2008 |
| Foreign Muck Limited | Hospitality | 2018 |
| Fortune Takeaway Limited | Hospitality | 2021 |
| Four Seasons (Wallcoverings) | | 1999 |
| FOUR10 Automotive & Media Ltd | Wholesale & retail | 2021 |
| Franklin Property Services (SW) Limited | Real estate | 2018 |
| Frega Limited | Information & communication | 2017 |
| Fresh N Local Ltd | Wholesale & retail | 2025 |
| Frosted Derp Studios Limited | Information & communication | 2024 |
| Function Junction (SW) Ltd | Extraterritorial | 2011 |
| Future Build Supplies Limited | Wholesale & retail | 2013 |
| Futurecross MX Ltd | Wholesale & retail | 2025 |
| G J Lambert Consultancy Limited | Professional & scientific | 2021 |
| G Johns Building Services Ltd | Construction | 2019 |
| G.E. Developments Ltd | Real estate | 1995 |
| G6 PVT Limited | Hospitality | 2023 |
| Gala Property Developments Ltd | Real estate | 2021 |
| Garbett Ltd | Hospitality | 2026 |
| Gardant Security Limited | Administrative & support | 2014 |
| Garden Court Saltash Management Limited | Real estate | 2017 |
| GAS Jack Group Ltd | Construction | 2015 |
| GB Pipelines Ltd | Construction | 2024 |
| GDW Plumbing and Heating Limited | Construction | 2023 |
| Gentle on the Planet Ltd | Administrative & support | 2017 |
| GHP Hospitality Ltd | Wholesale & retail | 2013 |
| Ginga Business Consultancy Ltd | Professional & scientific | 2020 |
| Globalstreet Investments Limited | Professional & scientific | 2008 |
| Golden Arrow Management Limited | Professional & scientific | 1998 |
| Goldwhite Estates Ltd | Real estate | 2024 |
| Goldwhite Ltd | Professional & scientific | 2021 |
| Golf Access Ltd | Wholesale & retail | 2018 |
| Good Partnership Ltd | Information & communication | 2012 |
| Goodun Creative Limited | Professional & scientific | 2025 |
| Gould & Sons Construction & Surfacing Ltd | Construction | 2025 |
| Goulty Performance Ltd | Health & social care | 2025 |
| Gracenote Promotion Ltd | Arts & recreation | 2024 |
| Graeme Harvey Properties Ltd | Real estate | 2024 |
| Green Tech Solar Ltd | Manufacturing | 2024 |
| Greenscombe Accounting Ltd | Professional & scientific | 2021 |
| Greenshoot Investments Limited | Financial services | 1999 |
| Gregory's Garage Limited | Wholesale & retail | 2003 |
| Gregson Investment Management Ltd | Real estate | 2011 |
| Greyedge Protection Ltd | Administrative & support | 2025 |
| Grimwood Bricklaying South West Ltd | Construction | 2024 |
| Grindlay Street Managers Ltd | Real estate | 2017 |
| Grove Nurseries Ltd | Other services | 2015 |
| Grumpy GIT Clothing Ltd | Wholesale & retail | 2009 |
| Gryphon Property Investments Ltd | Hospitality | 2023 |
| GS Lilley Holdings Ltd | Financial services | 2025 |
| GSL Media Ltd | Other services | 2013 |
| Gunnislake Garage Limited | Wholesale & retail | 2021 |
| GUY Hannaford Limited | Real estate | 2021 |
| Guys (SW) Ltd | Hospitality | 2022 |
| Gymvikings Ltd | Wholesale & retail | 2016 |