| Environmental Cooling Services Ltd | Construction | 2003 |
| Envirow Ltd | Manufacturing | 2023 |
| Envision People Ltd | Administrative & support | 2022 |
| Epic Niwas Ltd | Real estate | 2024 |
| Epsl Limited | Real estate | 2010 |
| Epworks Ltd | Education | 2025 |
| Equalpremium Property Management Limited | Households | 1993 |
| Equator Gold Limited | Mining & quarrying | 2011 |
| Equilibrium Coaching Group Ltd | Administrative & support | 2017 |
| Equine & Rural Planning Ltd | Construction | 2016 |
| Equine Construction Limited | Construction | 2012 |
| Equinox (Cardiff) Management Company Limited | Households | 2008 |
| Equirent Horse Transport Limited | Transport & logistics | 2024 |
| Equistar Holdings Limited | Real estate | 2022 |
| Equistar Veterinary Services Limited | Professional & scientific | 2014 |
| Equitas Solutions Group Ltd | Professional & scientific | 2025 |
| Equity Global Ltd | Real estate | 2024 |
| ER Rescue Ltd | Professional & scientific | 2020 |
| Ereuna Ltd | Professional & scientific | 2025 |
| Eridge House (Holdings) Limited | Financial services | 2017 |
| Eridge House Limited | Education | 2001 |
| Erigone Property Limited | Construction | 2012 |
| Eritina Premium Limited | Wholesale & retail | 2025 |
| Erlinda Teresa Holden Ltd | Extraterritorial | 2022 |
| Erprecruit Ltd | Information & communication | 2018 |
| ES Roofing & Building Ltd | Construction | 2026 |
| Esdon Architecture Limited | Professional & scientific | 2016 |
| Esdtopco Ltd | Wholesale & retail | 2022 |
| Esher Homes Limited | Professional & scientific | 2008 |
| Esmae Delivery Solutions Ltd | Transport & logistics | 2023 |
| Especially Dogs Limited | Wholesale & retail | 2021 |
| Espiga Bakehouse Ltd | Manufacturing | 2026 |
| Esprit-Connections Limited | Wholesale & retail | 2015 |
| Essel Holdings (Salisbury) Limited | Real estate | 1961 |
| Essenn Group Ltd | Wholesale & retail | 2025 |
| Esskay Management Services LLP | | 2012 |
| Estate Land and Property Management Ltd | Administrative & support | 2018 |
| ET Projects Ltd | Professional & scientific | 2021 |
| Etag Fixings UK Limited | Wholesale & retail | 2011 |
| Etang DES Greens Fishery Ltd | Agriculture & fishing | 2025 |
| Etello Care Limited | Information & communication | 2022 |
| Etello Limited | Information & communication | 2022 |
| Etello Services Limited | Information & communication | 2022 |
| Eternal Glow Beauty Limited | Other services | 2026 |
| Ethc Ltd | Professional & scientific | 2010 |
| Ethical Wealth Limited | Financial services | 2021 |
| ETN Glass and Gutters Ltd | Construction | 2022 |
| Etruscan (UK) Limited | Wholesale & retail | 1997 |
| Etsa CIC | Other services | 2010 |
| Euro-American Foods Limited | Agriculture & fishing | 1998 |
| Europa Leisure (UK) Limited | Wholesale & retail | 1987 |
| Europarc Atlantic Isles | Administrative & support | 2006 |
| European Plastics Distributors' Association | Other services | 2018 |
| European Student Placement Agency Limited | Administrative & support | 2012 |
| Eurospa Limited | Extraterritorial | 2003 |
| EV Developments Limited | Construction | 2020 |
| Evans Cabinetmakers and Joinery Limited | Manufacturing | 2020 |
| Evansis Property Intelligence Limited | Real estate | 2016 |
| Evaya Ltd | Transport & logistics | 2025 |
| EVE Meadows (Haughley) Management Company Limited | Households | 2020 |
| EVE of ST Agnes Limited | Manufacturing | 2011 |
| Evenflow CPG Limited | Professional & scientific | 2021 |
| Eventfootprints Limited | Information & communication | 2023 |
| Eventra Services Ltd | Professional & scientific | 2025 |
| Eventus Hire Ltd | Hospitality | 1999 |
| Evercoat Limited | Real estate | 1994 |
| Everconnect Limited | Financial services | 2002 |
| Evergreen (Lnfv) Management Company Limited | Households | 2006 |
| Everleigh Farm Shop Limited | Real estate | 2001 |
| Everyday Property Care Ltd | Construction | 2021 |
| Everything Art Projects Ltd | Arts & recreation | 2023 |
| Everything Corporation Ltd | Financial services | 2024 |
| Evo-Tec Installation Limited | Administrative & support | 2017 |
| Evolution (Stourbridge) Property Management Limited | Real estate | 2011 |
| Evolution Builders Limited | Construction | 2023 |
| Evolution Defence Ltd | Wholesale & retail | 2023 |
| Evolution Motor Company Salisbury Limited | Wholesale & retail | 2021 |
| Evolution Properties Salisbury Limited | Real estate | 2025 |
| Evolution Skydiving Ltd | Education | 2021 |
| Evolve Decorating Ltd | Construction | 2019 |
| Evopole Ltd | Administrative & support | 2021 |
| Evosyn Ltd. | Information & communication | 2017 |
| EWC Advisers Ltd | Administrative & support | 2010 |
| EWE Tree Cafe LLP | | 2005 |
| Excelent CUT Barbers Ltd | Other services | 2023 |
| Exec Connect UK Ltd | Transport & logistics | 2015 |
| EXF Reading Limited | Professional & scientific | 2025 |
| Exit Factor UK Limited | Professional & scientific | 2025 |
| Experient Consulting Limited | Information & communication | 2015 |
| Expired Light Ltd | Professional & scientific | 2025 |
| Explosive Realisation & Education Ltd | Professional & scientific | 2024 |
| Expressair Sameday Limited | Transport & logistics | 1991 |
| Expression Events Ltd | Administrative & support | 2016 |
| Expression Group Ltd | Administrative & support | 2020 |
| Exquisite Landscapes Limited | Administrative & support | 2021 |
| Extrafair Limited | Administrative & support | 2007 |
| EYE Connect Ltd | Administrative & support | 2018 |
| EYE Surgery Ltd | Health & social care | 2011 |
| Eyedoctor.London Ltd | Health & social care | 2016 |
| Eyedoctors.London Limited | Financial services | 2020 |