| Star Quantum Limited | Wholesale & retail | 2022 |
| Star Route Travel Limited | Administrative & support | 2025 |
| Star Shoes Limited | Wholesale & retail | 1987 |
| Starboy Menswear Ltd | Wholesale & retail | 2025 |
| Stargoat Games Ltd | Information & communication | 2021 |
| Starlight Heating Limited | Construction | 2018 |
| Starlight Publishing Ltd | Manufacturing | 2025 |
| Starnote Limited | Professional & scientific | 1998 |
| Starpwr Ltd | Wholesale & retail | 2024 |
| Stars Alterations and DRY Cleaners Ltd | Professional & scientific | 2025 |
| Stars DRY Cleaners Limited | Other services | 2022 |
| Stars Supplies Ltd | Wholesale & retail | 2021 |
| Start in Salford | Health & social care | 1999 |
| State Nominees 2 Limited | Extraterritorial | 2019 |
| Statebourne Ltd | Real estate | 2004 |
| Station Cocktail Bar & Grill Limited | Hospitality | 2018 |
| Station RD. (Turton) Limited | Households | 2010 |
| Station Road ASH Estates Limited | Other services | 2023 |
| Stay Ezzi Ltd | Hospitality | 2026 |
| Staycay Management Limited | Real estate | 2023 |
| Staycay Rental Ltd | Real estate | 2022 |
| Steam Pods Ltd | Health & social care | 2026 |
| Steamforged Games Ltd | Wholesale & retail | 2014 |
| Steamforged Holdings Limited | Manufacturing | 2017 |
| Stedetradsteel Engineering Limited | Professional & scientific | 2021 |
| Stedetradsteel. Ltd | Mining & quarrying | 2005 |
| Steel Foundry Crossfit Ltd | Arts & recreation | 2023 |
| Steelred Limited | Real estate | 2020 |
| Stefa Property Ltd | Real estate | 2025 |
| Stein Property Ltd | Real estate | 2026 |
| Stella J Properties Ltd | Real estate | 2024 |
| Stellar Consulting Group Limited | Administrative & support | 2024 |
| Stellify Installations Ltd | Construction | 2019 |
| Step by Step Dancing Limited | Arts & recreation | 2013 |
| Step to Shelter Merseyside CIC | Health & social care | 2025 |
| Stepholt Ltd | Information & communication | 2026 |
| Stepper-Ton Ltd | Other services | 2024 |
| Steprite Ltd | Wholesale & retail | 1998 |
| Steptown Limited | Extraterritorial | 2007 |
| Sterk Digitaal Ltd | Professional & scientific | 2024 |
| Sterling Agents Ltd | Real estate | 2022 |
| Sterling Blank Ltd | Construction | 2013 |
| Sterling Convenience Ltd | Wholesale & retail | 2025 |
| Stern's Books & Gifts Ltd | Wholesale & retail | 2016 |
| Stevenson Nominees Ltd | Professional & scientific | 2013 |
| Steward Nominees Limited | Extraterritorial | 2006 |
| Sthenos Healthcare Ltd | Health & social care | 2025 |
| Sti.R Developments Limited | Construction | 2011 |
| Stillmell NO. 2 Limited | Real estate | 2020 |
| Stinders Homes Construction Limited | Construction | 2021 |
| Stinders Homes Limited | Construction | 2021 |
| Stinders Homes SPV 1 Limited | Construction | 2021 |
| Stinders Homes SPV 2 Limited | Construction | 2021 |
| Stinders Homes SPV 3 Limited | Construction | 2022 |
| Stinders Homes SPV 4 Limited | Construction | 2023 |
| Stirling Silver Enterprises Limited | | 1980 |
| STK Traders Ltd | Wholesale & retail | 2021 |
| STL Solutions Limited | Hospitality | 2019 |
| Stocks Hall Care Homes (2) Limited | Construction | 1991 |
| Stolarczyk Properties Ltd | Real estate | 2020 |
| Stone Academic Services Ltd | Education | 2023 |
| Stone's Edge Limited | Real estate | 2016 |
| Stonebridge Commercial Limited | Construction | 2026 |
| Stonebridge Estates (NO.1) Limited | Households | 2016 |
| Stonebridge Estates (NO.2) Limited | Households | 2016 |
| Stonedale 2 Limited | Real estate | 2020 |
| Stonedale Limited | Real estate | 2020 |
| Stonedale Properties 2 Limited | Real estate | 2020 |
| Stonedale Properties Limited | Real estate | 2020 |
| Stonefield Ventures Limited | Wholesale & retail | 2025 |
| Stonegrid Utilities Ltd | Administrative & support | 2026 |
| Stonly Brokers Limited | Households | 2024 |
| Stonly Trading Limited | Households | 2024 |
| Stonyside Limited | Real estate | 1978 |
| Store Street Investments Limited | Administrative & support | 2022 |
| Store Street TOO Limited | Administrative & support | 2022 |
| Stpp International Ltd | Administrative & support | 2025 |
| STR Technology S.R.L Ltd | Other services | 2025 |
| Straight Lines and Circles Ltd | Arts & recreation | 2022 |
| Straight Lines and Circles Marketing Ltd | Professional & scientific | 2025 |
| Strategy Advisory Board Ltd | Professional & scientific | 2017 |
| Strategyhouse Communications Ltd | Professional & scientific | 2023 |
| Streaming Broadcast Services Limited | Information & communication | 2024 |
| Street Design Partnership Limited | Professional & scientific | 2015 |
| Strelisk Ltd | Real estate | 2025 |
| Stride X Ltd | Wholesale & retail | 2025 |
| Stridemed Ltd | Information & communication | 2024 |
| Strivast Ltd | Manufacturing | 2026 |
| Strong Legal Ltd | Professional & scientific | 2025 |
| Strong Web Studio Ltd | Information & communication | 2019 |
| Stubbs Garden MAN Co Limited | Households | 2024 |
| Studio 96 Dance Academy CIC | Education | 2018 |
| Studio Makonam Ltd | Professional & scientific | 2023 |
| Studio Place (Failsworth) Ltd | Construction | 2025 |
| Studio Place (Glazebury) Ltd | Construction | 2024 |
| Studio Place (Hadbutt) Ltd | Construction | 2024 |
| Studio Place (Heyside) Ltd | Construction | 2025 |
| Studio Place (Langho) Ltd | Construction | 2025 |
| Studio Place (Sale) Ltd | Construction | 2026 |
| Studio Place Developments Ltd | Construction | 2020 |