| DP Direct Ltd | Professional & scientific | 2025 |
| DP Play Limited | Health & social care | 2022 |
| DPM International Ltd | Professional & scientific | 2025 |
| DPM Trading Ltd | Wholesale & retail | 2016 |
| DR AI Prac Ltd | Professional & scientific | 2022 |
| DR AMR Elraggal Ltd | Health & social care | 2026 |
| DR David Hibbert Medical Services Limited | Other services | 2016 |
| DR MB Medical Services Ltd | Health & social care | 2025 |
| DR. ME Limited | Professional & scientific | 2011 |
| DR. Ronny Farah Ltd | Health & social care | 2022 |
| DRA Facades Ltd | Construction | 2026 |
| Draff Facades & Fenestration Ltd | Construction | 2024 |
| Dragon Burger Box Salford Ltd | Hospitality | 2025 |
| Dragon Lane Holdings 1 LLP | | 2015 |
| Dragon Lane Holdings 2 LLP | | 2015 |
| Dragon Lane LLP | | 2015 |
| Dragon's Platinum Limited | Other services | 2021 |
| Dream Coach Ltd | Information & communication | 2025 |
| Dream House NW Limited | Real estate | 2020 |
| Dream Media and Business Affairs Ltd | Professional & scientific | 2023 |
| Dream Scape Homes Ltd | Real estate | 2025 |
| Dream Your Party Limited | Hospitality | 2023 |
| Dribben Investments Ltd | Real estate | 2018 |
| Dribco Ltd | Financial services | 2024 |
| Drillzstays Ltd | Hospitality | 2015 |
| Drive Noble Ltd | Education | 2025 |
| Drive the Revolution Ltd | Wholesale & retail | 2019 |
| Drive-Ev Ltd | Wholesale & retail | 2021 |
| Driveway Estates Ltd | Real estate | 2025 |
| Driving Express Ltd | Information & communication | 2026 |
| Drizl Ltd | Hospitality | 2026 |
| Drop Outlet 1 Limited | Wholesale & retail | 2024 |
| Droshthepod Ltd | Health & social care | 2025 |
| Drujam Ltd | Wholesale & retail | 2020 |
| DRY Zone Umbrella Ltd | Manufacturing | 2024 |
| Drywall Machines Ltd | Construction | 2017 |
| DS Mentoring Limited | Professional & scientific | 2023 |
| DS Rose Property Investments Ltd | Real estate | 2026 |
| DSB Facades Ltd | Construction | 2023 |
| DSE Estates Ltd | Real estate | 2025 |
| DSL Trading Ltd | Professional & scientific | 2016 |
| Dspt Limited | Administrative & support | 2025 |
| Dstream Ltd | Real estate | 2020 |
| DT Analytics Ltd | Information & communication | 2025 |
| DT Global Trading Ltd | Wholesale & retail | 2016 |
| DTA Express Ltd | Transport & logistics | 2024 |
| DTA Investments Ltd | Real estate | 2022 |
| DTH Property Group Ltd | Real estate | 2024 |
| Dthpropertylettings Ltd | Real estate | 2024 |
| DTP Infinities Corporation Limited | Financial services | 2019 |
| DTP Supplies Limited | Extraterritorial | 1998 |
| Duchy Stores Ltd | Wholesale & retail | 2018 |
| Dudley Coles Limited | Extraterritorial | 1945 |
| Dulcestay Limited | Real estate | 2022 |
| Dumundo Ltd | Wholesale & retail | 2020 |
| Dunham Properties Limited | Real estate | 2025 |
| Dunia Asia Limited | Professional & scientific | 2025 |
| Dunkerley Estates Ltd | Real estate | 2018 |
| Dunkirk Developers (North West) Limited | Construction | 2018 |
| Duntherm Ltd | Extraterritorial | 2013 |
| DUO Libra Agency Limited | Information & communication | 2023 |
| Durabond Resin Solutions Ltd | Construction | 2025 |
| Durafurn Limited | Manufacturing | 2014 |
| Duralec UK Limited | Professional & scientific | 2000 |
| Durley Investments Ltd | Real estate | 2023 |
| Dushinski Limited | Health & social care | 2016 |
| Dustra Ltd | Manufacturing | 2025 |
| Dustyhall Ltd | Extraterritorial | 2014 |
| Dvsn Construction Services Ltd | Administrative & support | 2026 |
| Dvtr Properties Ltd | Real estate | 2026 |
| DW (Holdings) 2021 Limited | Financial services | 2021 |
| DW (Property) 2021 Limited | Real estate | 2021 |
| Dylan Nkomo Solutions Ltd | Health & social care | 2026 |
| Dynamic Products Limited | Professional & scientific | 1994 |
| Dynamique Consult Ltd | Professional & scientific | 2025 |
| Dynamique Consulting Ltd | Professional & scientific | 2024 |
| Dyrham Park Limited | Construction | 2016 |
| E & B Estates Ltd | Real estate | 2017 |
| E & C UN Ltd | Real estate | 2022 |
| E & S Property Services (North West) Limited | Real estate | 2017 |
| E Nixon Consultant Limited | Health & social care | 2017 |
| E P Cars Ltd. | Wholesale & retail | 2011 |
| E&H Holdings Ltd | Information & communication | 2025 |
| E&I Hospitality Ltd | Financial services | 2025 |
| E-Com Live Ltd | Wholesale & retail | 2025 |
| E-Gents Ltd | Health & social care | 2024 |
| E-Shop Global Limited | Wholesale & retail | 2025 |
| E-Sunrise Distributors.Com Limited | Wholesale & retail | 2003 |
| E.H. Digital Marketing Ltd | Professional & scientific | 2020 |
| E.S Service Group Ltd | Real estate | 2015 |
| Eacc Solutions Ltd | Administrative & support | 2018 |
| Eaconfield Limited | Professional & scientific | 1994 |
| EAE Energy Solutions Limited | Construction | 2026 |
| Eagle BJ Holdings Limited | Financial services | 2021 |
| Eagle Coffee Limited | Hospitality | 2024 |
| Eagle Estates Holdings Limited | Other services | 2019 |
| Eagle Homes Financial Services Ltd | Financial services | 2024 |
| Eagle Legals Limited | Professional & scientific | 2025 |
| Eagle Shipping Services Limited | Transport & logistics | 2013 |
| Eagle Wing Fashion Ltd | Wholesale & retail | 2023 |