| Debs Home Organising Limited | Administrative & support | 2025 |
| Debsco Limited | Real estate | 2017 |
| Debsdov (NO.1) Ltd | Financial services | 2020 |
| Debt in Control Limited | Extraterritorial | 2006 |
| Decowall Limited | Construction | 2023 |
| Deeds Global Consultancy Ltd | Education | 2025 |
| Deemesh Oudit Limited | Health & social care | 2015 |
| Dekarh Luxury Cleaning Ltd | Administrative & support | 2026 |
| Delaware Legal Services Limited | Professional & scientific | 2023 |
| Deli Lama Cafe Bar Limited | Hospitality | 2019 |
| Deli Lama Community Co-Op Limited | Hospitality | 2024 |
| Deli Neste Salford Limited | Wholesale & retail | 2022 |
| Delite Construction Limited | Real estate | 2025 |
| Delmont Properties Ltd | Real estate | 2016 |
| Delomore Estates Ltd | Real estate | 2014 |
| Delrin UK Ltd | Wholesale & retail | 2023 |
| Deluxe Achievers Ltd | Wholesale & retail | 2024 |
| Deluxe Beauty Lounge Ltd | Other services | 2023 |
| Deluxe City Group Ltd | Hospitality | 2026 |
| Demif Art Project Ltd | Wholesale & retail | 2024 |
| Demure Educational Services Limited | Education | 2025 |
| Denfam Limited | Financial services | 2022 |
| Denis Clifford Site Services Ltd. | Construction | 2015 |
| Denisa Arizona Limited | Wholesale & retail | 2024 |
| Denkko Services Limited | Professional & scientific | 2025 |
| Denovale Limited | Real estate | 1987 |
| Dent Company Manchester Ltd | Wholesale & retail | 2013 |
| Dental Bockmann Ltd | Health & social care | 2018 |
| Dentechnica UK Ltd | Manufacturing | 2026 |
| Dention Limited | Education | 2025 |
| Dentith Family Co Limited | Manufacturing | 2019 |
| Denton Construction & Electrical Limited | Construction | 1989 |
| Denull Properties and Investment Limited | Real estate | 2023 |
| Deos Capital Ltd | Real estate | 2025 |
| Deoxy Tech Limited | Information & communication | 2025 |
| Depom Ltd | Wholesale & retail | 2026 |
| Depositlock Ltd | Financial services | 2022 |
| Derma LUX Pro Ltd | Administrative & support | 2019 |
| DES GP Services Ltd | Health & social care | 2020 |
| Desap Enterprises Limited | Information & communication | 2014 |
| Desap Limited | Information & communication | 2019 |
| Desarai Studios Ltd | Wholesale & retail | 2026 |
| Desert Rose Maison Ltd | Extraterritorial | 2024 |
| Designbyzh Ltd | Professional & scientific | 2022 |
| Desina Properties Limited | Real estate | 2021 |
| Desserts House Limited | Hospitality | 2023 |
| Destined Projects Ltd | Administrative & support | 2025 |
| Devex Connect Ltd | Administrative & support | 2024 |
| Devine Afro Kitchen Ltd | Hospitality | 2025 |
| Devine Industry Ltd | Financial services | 2025 |
| Devious Limited | Information & communication | 2018 |
| Devonshire Estates MCR Ltd | Real estate | 2022 |
| Devoted Guardian Care Limited | Health & social care | 2016 |
| Dewu Homes Ltd | Real estate | 2024 |
| Dewu Limited | Health & social care | 2016 |
| Dexspace Ltd | Information & communication | 2026 |
| Dextrapay Ltd. | Administrative & support | 1992 |
| DFH Property Limited | Real estate | 2018 |
| DFN (M'Cr) Services Ltd | Other services | 2019 |
| DFS Access Ltd | Other services | 2018 |
| Dfsi M25 Ltd | Professional & scientific | 2021 |
| DG Freelance NVQ Assessors Ltd | Education | 2020 |
| DGB Corporation Ltd | Health & social care | 2025 |
| DGB Roofing and Building Services Ltd | Manufacturing | 2026 |
| DGI UK Group Limited | Wholesale & retail | 2017 |
| DGN Scaffolding Ltd | Construction | 2011 |
| DHH 2 Wirral Ltd | Real estate | 2020 |
| DHH 2 Wirral Subs Limited | Real estate | 2023 |
| DHH Albion Court Ltd | Real estate | 2020 |
| DHH Boxworks Manchester Ltd | Construction | 2020 |
| DHH Morecambe Ltd | Construction | 2023 |
| DHH Primley Park, Leeds Ltd | Construction | 2020 |
| DHP Trustee Company | Administrative & support | 1982 |
| Diamant Direct Ltd | Real estate | 2020 |
| Diamond Cleaning (NW) Ltd | Administrative & support | 2023 |
| Diamond Cutz NW Ltd | Wholesale & retail | 2025 |
| Diamond Home Cleaning Limited | Administrative & support | 2022 |
| Diamond Home Support (Bury Bolton) Limited | Administrative & support | 2023 |
| Diaquip Limited | Professional & scientific | 2014 |
| Diar & Siar Garden Services Ltd | Other services | 2025 |
| Diasell Ltd | Wholesale & retail | 2025 |
| Diba Imaging Ltd | Health & social care | 2025 |
| Dibby Theatre Ltd | Arts & recreation | 2021 |
| Dickens International Limited | Administrative & support | 1979 |
| Dickens Property Group Limited | Professional & scientific | 1997 |
| Dieten Ltd | Other services | 2025 |
| Difalabs Ltd | Information & communication | 2025 |
| DIG Media Limited | Arts & recreation | 2015 |
| Digeight Limited | | 1982 |
| Digger Limited | Information & communication | 1998 |
| Diggle Street Ltd | Real estate | 2021 |
| Digi-Pal Ltd | Manufacturing | 2015 |
| Digilisys Ltd | Information & communication | 2014 |
| Digital Ecom Ltd | Wholesale & retail | 2023 |
| Digitalalley Ltd | Information & communication | 2025 |
| Digitalised Limited | Professional & scientific | 2021 |
| Digitisenow Limited | Information & communication | 2007 |
| Dignity Complex Care Ltd | Health & social care | 2022 |
| Digset Limited | Construction | 2020 |
| Dikov Property Ltd | Real estate | 2025 |