| South East Preservation Limited | Construction | 2017 |
| Southbourne Properties Limited | Financial services | 2018 |
| Southern Counties Window Cleaning (F) Ltd | Administrative & support | 2018 |
| Southern Counties Window Cleaning (K) Ltd | Administrative & support | 2020 |
| Southern Prestige Ltd | Construction | 2017 |
| Sowdens Investments Ltd | Real estate | 2021 |
| Spark Industries Ltd | Information & communication | 2026 |
| Spencer Maynard W M Limited | Information & communication | 2019 |
| Spindrift Stores Limited | Wholesale & retail | 2025 |
| Sportmac UK Ltd | Construction | 2018 |
| SRB Electrical & Security Ltd | Construction | 2023 |
| Stag-Ac Ltd | Manufacturing | 2007 |
| Starfish Creative Limited | Professional & scientific | 2002 |
| Starlock Meadow Huts Ltd | Hospitality | 2024 |
| State of the Art Tattoo Limited | Other services | 2013 |
| Steenmarsh Ltd | Information & communication | 2016 |
| Stoma Alert Limited | Health & social care | 2025 |
| Strandgate Ltd | Hospitality | 2026 |
| Subject 2 Limited | Financial services | 2010 |
| Sugarloaf Marketing Limited | Professional & scientific | 2012 |
| Summer Court (Eastbourne) Limited | Households | 2004 |
| Sunset Creative Limited | Information & communication | 2009 |
| Superior Scaffolding Services Ltd | Construction | 2026 |
| Surface Matter Limited | Wholesale & retail | 2013 |
| Sushi Catering Ltd | Hospitality | 2023 |
| Sussex Decorating Ltd | Manufacturing | 2017 |
| Sussex House Management (TN38 0BN) Limited | Households | 2008 |
| Sussex Statics Ltd | Wholesale & retail | 2023 |
| Sussex Storehouse Ltd | Transport & logistics | 2018 |
| Sussex Systems Limited | Construction | 2009 |
| Swans House Residents Company Limited | Households | 1998 |
| Sweeneys of RYE Limited | Other services | 2023 |
| Swell Integrations Ltd | Construction | 2023 |
| T G Fast Foods Ltd | Hospitality | 2022 |
| Taskforce Property Services Limited | Water & waste | 2002 |
| Tatners Catering and Events Limited | Hospitality | 2014 |
| Technistaff Limited | Real estate | 1944 |
| Tekel Limited | Hospitality | 2025 |
| Tekeli Ecommerce Ltd | Wholesale & retail | 2026 |
| THE 281 London Road Right to Manage Company Limited | Households | 2008 |
| THE 32 Magdalen Road Right to Manage Company Limited | Extraterritorial | 2009 |
| THE 64 Clinic Limited | Health & social care | 2025 |
| THE Art of Stone (RYE) Ltd | Wholesale & retail | 2024 |
| THE Bakery at 89 Limited | Wholesale & retail | 2020 |
| THE Banana Pyjama Co. Ltd | Wholesale & retail | 2025 |
| THE Brilliant Branding Company Ltd | Wholesale & retail | 2020 |
| THE Brit List Ltd | Administrative & support | 2022 |
| THE Broad Oak Brede Ltd | Hospitality | 2009 |
| THE Burwash Consulting Group Limited | Professional & scientific | 2020 |
| THE Clam in Hastings Limited | Hospitality | 2023 |
| THE Colebrooke Centre for Evidence and Implementation | Professional & scientific | 2011 |
| THE Complete Cottage Care Company Ltd | Administrative & support | 2016 |
| THE Corn Exchange Management Limited | Households | 1998 |
| THE Darling Buds of Beckley Limited | Wholesale & retail | 2023 |
| THE FIG (RYE) Limited | Hospitality | 2015 |
| THE Gale & Dunn Partnership Ltd. | Professional & scientific | 1999 |
| THE Granary Spa Limited | Health & social care | 2015 |
| THE Great British Wine Company Ltd | Wholesale & retail | 2017 |
| THE Great Dixter Charitable Trust | Arts & recreation | 2010 |
| THE Hollow Seven Ltd | Households | 2024 |
| THE Hospitality PM Ltd | Construction | 2025 |
| THE Jolly Good Cleaning Company Ltd | Administrative & support | 2026 |
| THE Kind Table Limited | Wholesale & retail | 2022 |
| THE Kitesurf Centre Ltd | Arts & recreation | 2011 |
| THE Kitesurf Centre Shop Ltd | Wholesale & retail | 2018 |
| THE Light Salon Boost Limited | Wholesale & retail | 2018 |
| THE Light Salon Limited | Other services | 2014 |
| THE Meads (Battle) Limited | Households | 1999 |
| THE Mint in RYE Limited | Wholesale & retail | 2020 |
| THE Modern Spirits Company Ltd | Hospitality | 2016 |
| THE Multisport Adventure Racing Challenge LLP | | 2011 |
| THE Music Well Community Interest Company | Health & social care | 2010 |
| THE News and Wine Trading Ltd | Wholesale & retail | 2012 |
| THE Outside Inn at Landgate House Ltd | Arts & recreation | 2018 |
| THE Peasmarsh Chamber Music Festival Trust | Arts & recreation | 2002 |
| THE Peasmarsh Cider Company Limited | Manufacturing | 2017 |
| THE RAW VET Ltd | Manufacturing | 2019 |
| THE Salon RYE Limited | Other services | 2024 |
| THE Swell Organisation Ltd | Administrative & support | 2016 |
| THE Three Legs Brewing Company Limited | Manufacturing | 2014 |
| THE UK Concierge Company Limited | Other services | 2025 |
| THE Wall Windows & Construction Ltd | Construction | 2024 |
| THE Whatlington PUB Company Ltd. | Hospitality | 2002 |
| THE Window Wizard (RYE) Limited | Construction | 2006 |
| THE Workroom (RYE) Ltd | Professional & scientific | 2023 |
| Thebestofhastings Limited | Administrative & support | 2014 |
| Therapy Research Services Limited | Professional & scientific | 2014 |
| Thompson Waste Removal Ltd | Water & waste | 2021 |
| Thornton Financial Services Limited | Administrative & support | 2010 |
| Tilling Green Events CIC | Arts & recreation | 2024 |
| Titan Group MED (UK) Ltd | Health & social care | 2025 |
| Tollgate Development Company Limited | Construction | 1987 |
| Trade Car Sales Limited | Wholesale & retail | 1999 |
| Trail-Blazers Mentoring Ltd | Education | 1998 |
| Transformations (South East) Limited | Construction | 2010 |
| Tree Counties Contracting Ltd | Agriculture & fishing | 2024 |
| Trend Interiors Ltd | Wholesale & retail | 2018 |
| Trojan Gym Limited | Arts & recreation | 2022 |
| Trojan Supplements Limited | Wholesale & retail | 2023 |
| Trueform Dental Laboratory Limited | Health & social care | 2022 |