| HKE Ryde Restaurant Ltd | Hospitality | 2016 |
| HNK (London) Limited | Real estate | 2019 |
| Holeweye Ltd | Real estate | 2025 |
| Hollidge & Brown Ltd | Administrative & support | 2018 |
| Holofcener Limited | Arts & recreation | 1999 |
| Home Consultancy Ltd | Professional & scientific | 2011 |
| Home From Home Isle of Wight Ltd | Administrative & support | 2021 |
| Home IOW Limited | Real estate | 2003 |
| Homebray House RTM Company Limited | Households | 2017 |
| Homes & Homes Ltd | Other services | 2015 |
| Hong Kong Express IOW Ryde Ltd | Hospitality | 2022 |
| Hoofed Limited | Administrative & support | 2025 |
| Horace Architects Ltd | Professional & scientific | 2017 |
| House of Huns IOW Ltd | Arts & recreation | 2021 |
| House of Pancakes Limited(The) | Hospitality | 1962 |
| House of Wonder Ltd | Health & social care | 2021 |
| House of Zabre LLP | | 2017 |
| Howell Painting and Decorating Ltd | Construction | 2021 |
| HPD (IW) Ltd | Real estate | 2021 |
| Hptr Limited | Real estate | 2024 |
| HR & Wagh Travel Ltd | Administrative & support | 2026 |
| Hudson Built Ltd | Construction | 2025 |
| Humphray Associates Ltd | Other services | 2008 |
| Hungry Bear Catering Ltd | Hospitality | 2025 |
| Hunt & Partners (Ryde) Limited | Professional & scientific | 2016 |
| Hunter and BOO (UK) Limited | Wholesale & retail | 2019 |
| HWB Ground Works Limited | Construction | 2025 |
| I Binder Ltd | Health & social care | 2014 |
| I.P Improvements Ltd | Construction | 2022 |
| IAN ST James Limited | Arts & recreation | 2016 |
| Iconic Architecture Ltd | Professional & scientific | 2022 |
| ICT Media Ltd | Administrative & support | 2010 |
| Ifix Local Limited | Manufacturing | 2014 |
| Ignite Customs Ltd | Professional & scientific | 2020 |
| Iheartbuttons Limited | Professional & scientific | 2011 |
| Il-Optimum Ltd | Hospitality | 2018 |
| Imobi Studios Limited | Information & communication | 2011 |
| IN Hot Water? Limited | Construction | 2019 |
| IN House Chef Ltd | Hospitality | 2025 |
| IN the Garden IOW Ltd | Construction | 2026 |
| IN9 Limited | Professional & scientific | 2022 |
| Inca (IOW) Ltd | Professional & scientific | 2026 |
| Independent Social Solutions Limited | Professional & scientific | 2008 |
| Indigo Marine Ltd | Manufacturing | 2022 |
| Infinity Soloutions Ltd | Administrative & support | 2024 |
| Inishowen Court Residents Company Limited | Professional & scientific | 1989 |
| Inspired Endeavours Limited | Real estate | 2013 |
| Inspired Island Events Limited | Other services | 2019 |
| Inswig Limited | Professional & scientific | 2019 |
| Intellinexus Limited | Information & communication | 2025 |
| Inthebeginning Limited | Information & communication | 1997 |
| Inventions Limited | Information & communication | 2008 |
| Invictus Holdings IOW Ltd | Other services | 2019 |
| Invictus Medical Services Limited | Health & social care | 2016 |
| Invictus Properties & Lettings Holding Ltd | Other services | 2024 |
| IO Assist Ltd | Administrative & support | 2023 |
| IOW Animal Bedding Limited | Water & waste | 2024 |
| IOW Glass Ltd | Manufacturing | 2023 |
| IOW Hospitality Ltd | Hospitality | 2020 |
| IR Lettings Ltd | Real estate | 2024 |
| Irrational Theatre Limited | Arts & recreation | 2005 |
| Island Composites Limited | Manufacturing | 2021 |
| Island Concerns Ltd | Health & social care | 1992 |
| Island Consultancy Ltd | Professional & scientific | 2014 |
| Island Craftworks CIC | Education | 2026 |
| Island Echo Ltd | Information & communication | 2016 |
| Island Engineering Solutions Ltd | Manufacturing | 2019 |
| Island Estates Ltd | Real estate | 2023 |
| Island EYE Care Limited | Financial services | 2026 |
| Island Foods Limited | Manufacturing | 2001 |
| Island Healthcare Holdings & Contracting Limited | Real estate | 2017 |
| Island Healthcare Limited | Health & social care | 1995 |
| Island Healthcare Properties Limited | Real estate | 2015 |
| Island Jewellers Limited | Wholesale & retail | 2025 |
| Island Laser Works Limited | Professional & scientific | 2025 |
| Island Lettings Limited | Real estate | 2009 |
| Island Medical Clinic Ltd | Health & social care | 2025 |
| Island Medical Recruitments Ltd. | Administrative & support | 2022 |
| Island New Developments Ltd | Construction | 2017 |
| Island Pest Control Limited | Agriculture & fishing | 2005 |
| Island Smugglers Group Ltd | Wholesale & retail | 2026 |
| Island Solar Limited | Construction | 2024 |
| Island Speedway (IOW) Limited | Arts & recreation | 1997 |
| Island Stoves Ltd | Construction | 2025 |
| Island Survey Systems Limited | Professional & scientific | 1993 |
| Island Telecom Ltd | Information & communication | 2025 |
| Island Telecom Marine Ltd | Information & communication | 2025 |
| Island Trade Window Supplies Limited | Manufacturing | 1997 |
| Island Vetcare Ltd | Professional & scientific | 2017 |
| Island Wight Properties LLP | | 2024 |
| Island Yurts Limited | Manufacturing | 2012 |
| Islandwide General Maintenance Ltd. | Construction | 2022 |
| Islandwide Logistics Ltd | Transport & logistics | 2024 |
| Isle Connect Ltd | Information & communication | 2022 |
| Isle of Wight Accountants Ltd | Professional & scientific | 2015 |
| Isle of Wight Boilers Limited | Construction | 2024 |
| Isle of Wight BUS & Coach Museum Limited | Arts & recreation | 2000 |
| Isle of Wight Car Club Limited | Arts & recreation | 1967 |
| Isle of Wight Cocktail Co. Ltd | Wholesale & retail | 2022 |
| Isle of Wight Distillery Ltd | Manufacturing | 2014 |