| Peak Performance Sussex Ltd | Arts & recreation | 2016 |
| Pearcey-Taggart Limited | Construction | 2019 |
| Pentire Homes Limited | Real estate | 2019 |
| Performance Teachers Ltd. | Education | 2018 |
| Peter Davey Limited | Professional & scientific | 2006 |
| Pink Letters Ltd | Wholesale & retail | 2023 |
| Planet Rustington Ltd | Hospitality | 2018 |
| Pocketweather Limited | Information & communication | 2006 |
| Pollsons Ltd | Real estate | 2024 |
| Post Cool Media Limited | Arts & recreation | 2012 |
| Pragmatic Software Design Limited | Information & communication | 2012 |
| Precious Plumbing & Heating Ltd | Construction | 2025 |
| Projogo Limited | Information & communication | 2018 |
| Raspberry Crumble Limited | Information & communication | 2025 |
| Ratemedia Limited | Information & communication | 2008 |
| RC Utility Limited | Construction | 2023 |
| RCJ Consulting Limited | Wholesale & retail | 2018 |
| Rebecca Bennett Podiatry Ltd | Health & social care | 2016 |
| Rebecca Jacqueline (Hove) Ltd | Health & social care | 2024 |
| Red Zebra Lettings Limited | Real estate | 2023 |
| Regency Spaces Ltd | Administrative & support | 2023 |
| RFC Finance Ltd | Financial services | 2026 |
| Right Brain Stories Limited | Professional & scientific | 2020 |
| Right on Comms Limited | Professional & scientific | 2012 |
| RMS Sussex Limited | Wholesale & retail | 2018 |
| Rooftop Mindset Ltd | Information & communication | 2024 |
| Rosi Walden Ltd | Real estate | 2023 |
| Run Love Festival Ltd | Arts & recreation | 2025 |
| Rustington Manor Hotel Limited | Hospitality | 2019 |
| S D Pullen Brickwork Limited | Construction | 2005 |
| S.P.S. Pubs Limited | Hospitality | 2005 |
| SAM West Farriery Ltd | Agriculture & fishing | 2025 |
| Same Boat Music Limited | Information & communication | 2018 |
| Samson Holder Joinery Ltd | Manufacturing | 2025 |
| Sapient Software Solutions Limited | Information & communication | 2023 |
| SC MSR Limited | Professional & scientific | 2023 |
| Seadown House Limited | Health & social care | 2012 |
| Sechel Letz Limited | Real estate | 2023 |
| SECOND2NONE School Support Limited | Administrative & support | 2020 |
| Securit Ropes & Packaging Ltd | Wholesale & retail | 1994 |
| Shirlands Court (Rustington) Freehold Limited | Households | 2025 |
| Shoreham Consultants Limited | Information & communication | 2007 |
| Shutters by the Sea Limited | Construction | 2024 |
| Sicamconstruction Ltd | Manufacturing | 2025 |
| Sigma Engineered Solutions Limited | Administrative & support | 2007 |
| Silverfern Logistics Limited | Transport & logistics | 2025 |
| Smoke Puppy (Nollaig) Ltd | Information & communication | 2026 |
| Spacebar Touring Limited | Arts & recreation | 2024 |
| Spectrum Investments Limited | Real estate | 2007 |
| Spencer Haynes Limited | Construction | 2022 |
| SPT Haywards Heath Ltd | Extraterritorial | 2023 |
| Spt-H Ltd | Financial services | 2023 |
| STC Mechanical Estimating Ltd | Professional & scientific | 2025 |
| Step Forward Latin America Limited | Professional & scientific | 2023 |
| Sterileflat Antibacterial Medical Keyboards Ltd | Extraterritorial | 2012 |
| Steve Cahill Consultancy Limited | Professional & scientific | 2023 |
| Steven Robinson Flooring Limited | Construction | 2022 |
| Stizzle Things Limited | Administrative & support | 2024 |
| Stuart Jones Ltd | Manufacturing | 1977 |
| Supertrackuk Limited | Education | 2020 |
| Support for Diabetes | Administrative & support | 2014 |
| Sussex Drone Pilot Limited | Information & communication | 2025 |
| SV Warren Limited | Extraterritorial | 2018 |
| Sveva Limited | Administrative & support | 2006 |
| SWP29 Ltd | Professional & scientific | 2023 |
| Tarring Clinical Research Limited | Information & communication | 2014 |
| Taxify Limited | Professional & scientific | 2016 |
| Tcsk Consulting Limited | Administrative & support | 2017 |
| Texell Systems Limited | Construction | 2006 |
| THE Antique Dispensary Limited | Wholesale & retail | 1998 |
| THE Sign Professionals Ltd | Professional & scientific | 2018 |
| THE Silent DJS Limited | Arts & recreation | 2023 |
| The-Parish.Com Limited | Professional & scientific | 2012 |
| TPC Retreats Ltd | Other services | 2024 |
| Trafalgar Group Limited | Professional & scientific | 2008 |
| Trafalgar Sussex Ltd | Financial services | 2023 |
| Training Safety Limited | Education | 2007 |
| Transparent Double Glazing Limited | Construction | 2026 |
| Trimec (Europe) Limited | Professional & scientific | 2000 |
| Umbrella Media Ltd | Information & communication | 2024 |
| Underground Overture Limited | Professional & scientific | 2019 |
| Uraeus Technology Limited | Administrative & support | 2015 |
| Vero CUP Limited | Manufacturing | 2025 |
| Visuals Team Limited | Information & communication | 2022 |
| Volan Systems Ltd | Manufacturing | 2024 |
| Washington Coachworks (Sussex) Ltd | Wholesale & retail | 2011 |
| Waterbanner Limited | Construction | 2007 |
| Wave Controls Limited | Wholesale & retail | 2020 |
| Wayward Tariq Film Limited | Information & communication | 2026 |
| WE ARE MC2 Ltd | Professional & scientific | 2011 |
| Wicks Analytics Limited | Professional & scientific | 2019 |
| Wicks Carpentry & General Builders Limited | Construction | 2004 |
| Wimbledon Building Services Ltd | Construction | 2024 |
| Wired for Life Electrical Services Limited | Construction | 2014 |
| Woodlands Rustington Management Company Ltd | Real estate | 2011 |
| Woodleigh Limited | Professional & scientific | 2008 |
| Wootton George Consulting Limited | Professional & scientific | 1998 |
| Wubuki Ltd | Professional & scientific | 2016 |
| Y9 NDB Ltd | Financial services | 2022 |
| Your Holiday LET Management Ltd | Real estate | 2025 |