| DB FFF Coaching LLP | | 2025 |
| DC Property Partners Ltd | Real estate | 2023 |
| DC Pumps Limited | Manufacturing | 2025 |
| DCD Design Ltd | Manufacturing | 2007 |
| Dcrm Consulting Limited | Professional & scientific | 2019 |
| DCS Residential Ltd | Real estate | 2017 |
| Deadwood Services Limited | Construction | 2015 |
| Dean Barbers Ltd | Other services | 2026 |
| Deene Property Ltd | Real estate | 2023 |
| Deesandylinc Limited | Health & social care | 2026 |
| Deetee Limited | Administrative & support | 2024 |
| Defco Ltd | Professional & scientific | 2025 |
| DEL BOY Technologies Ltd | Information & communication | 2022 |
| Delaney Property Investments Limited | Real estate | 2021 |
| Delaney Property Management Limited | Real estate | 2022 |
| Demaj Construction Ltd | Construction | 2019 |
| Demaj Investment Ltd | Real estate | 2025 |
| Demon K9 Ltd | Administrative & support | 2026 |
| Denton Brothers Limited | Manufacturing | 2000 |
| Denton Tavara Limited | Professional & scientific | 2012 |
| Denver James Ltd | Real estate | 2020 |
| Derwent Furniture Limited | Wholesale & retail | 2020 |
| Desc-Top Limited | Manufacturing | 2024 |
| Designer Recruitment Ltd | Administrative & support | 2023 |
| Devise Designs Ltd | Professional & scientific | 2024 |
| Dewkon Projects UK Ltd | Construction | 2025 |
| Df&Gk Limited | Real estate | 2026 |
| DG2025 Limited | Information & communication | 2025 |
| Diamond Jobs Ltd | Administrative & support | 2025 |
| Diandy Ltd | Transport & logistics | 2025 |
| Digiproof AI Ltd | Information & communication | 2022 |
| Digital Event Solutions Ltd | Professional & scientific | 2022 |
| Digital X-Ray Engineering Ltd | Wholesale & retail | 2018 |
| Digitalmarketplace Ltd | Extraterritorial | 2020 |
| Dija Limited | Hospitality | 2009 |
| Direct Plant Sales Ltd | Wholesale & retail | 2001 |
| Disabledunity CIC | Health & social care | 2023 |
| Distinctive Flooring & Blinds Limited | Construction | 2017 |
| DJP Telecoms Limited | Information & communication | 2016 |
| DJR Scaffolding Ltd | Construction | 2025 |
| DK Realty Limited | Real estate | 2025 |
| DMC Encore Holdings Limited | Financial services | 2025 |
| Dmpk Consulting Services Ltd | Professional & scientific | 2025 |
| DNA Breaks Ltd | Wholesale & retail | 2026 |
| Dnwolfenden Limited | Professional & scientific | 2025 |
| Dobson Heating & Cooling Ltd | Construction | 2024 |
| Dolce FAR Niente Holdings Ltd | Financial services | 2025 |
| Doli Services Limited | Financial services | 2021 |
| DOM Cleaning Limited | Administrative & support | 2016 |
| Domestic Plumbing Heating and GAS Services Ltd | Construction | 2019 |
| Donewell Holdings Ltd | Hospitality | 2025 |
| Donewell Limited | Hospitality | 2024 |
| Donewell Properties Ltd | Real estate | 2019 |
| Doremi HX Ltd | Transport & logistics | 2025 |
| Dospinescu Ltd | Construction | 2018 |
| Double Undies Ltd | Wholesale & retail | 2025 |
| Dove Group Systems Ltd | Extraterritorial | 2017 |
| Dove House Motor Company Limited | Wholesale & retail | 2005 |
| Downs Steam Fair Ltd | Arts & recreation | 2024 |
| DR S Etemadi Dental Practice Ltd | Health & social care | 2016 |
| Drag Racing Limited | Administrative & support | 1997 |
| Dragon City 107 Limited | Hospitality | 2018 |
| Dragon Retail 536 Limited | Wholesale & retail | 2025 |
| Drains & Watermains Ltd | Water & waste | 2025 |
| Drgdrive Limited | Wholesale & retail | 2015 |
| Droptimum Limited | Wholesale & retail | 2015 |
| Drsj Legacy Ltd | Manufacturing | 2025 |
| DS & L Limited | Health & social care | 2015 |
| DSR Contracts Ltd | Other services | 2024 |
| Duguid Ltd | Education | 2019 |
| DV Kilpin Ltd | Real estate | 2013 |
| Dvkgold Ltd | Mining & quarrying | 2019 |
| DWA Property Ltd | Hospitality | 2017 |
| Dydy Ltd | Transport & logistics | 2012 |
| Dynamic Tooling Limited | Professional & scientific | 2011 |
| E & B Properties Limited | Real estate | 2022 |
| E Lamaj Ltd T/A Rushden Tyres Ltd | Wholesale & retail | 2015 |
| E&N Property Ltd | Real estate | 2025 |
| E.W.N. Wong Asset Management Limited | Administrative & support | 2012 |
| East Midlands Football Academy Ltd | Arts & recreation | 2023 |
| East Northants Child Contact Services - C.I.C. | Health & social care | 2014 |
| Echopeak Ltd | Professional & scientific | 2023 |
| Eco-Wave Solar Panels Limited | Construction | 2025 |
| Ecton Hall Management Limited | Real estate | 1988 |
| Edmi Services Limited | Administrative & support | 2013 |
| EDS24 Limited | Health & social care | 2014 |
| Edwardgracehope Investments Limited | Administrative & support | 2019 |
| EGA Properties Ltd | Real estate | 2019 |
| EGK Services Limited | Administrative & support | 2025 |
| Elects Wiring Ltd | Other services | 2018 |
| Element Building Ltd | Construction | 2025 |
| Element Property Services Ltd | Real estate | 2025 |
| Elimu Consulting Ltd | Information & communication | 2012 |
| Elisabeth Dyte Management Consultancy Limited | Households | 2020 |
| Elite Building & Property Maintenance Ltd | Construction | 2017 |
| Elite Clothing Limited | Manufacturing | 1997 |
| Elite Lead Generation Limited | Information & communication | 2024 |
| Elite Mobile Detailing Ltd | Administrative & support | 2024 |
| Elizabeth Elliott Consulting Ltd | Professional & scientific | 2024 |
| Elizabeth Nicholls Ltd | Professional & scientific | 2015 |