| Winders & Monaghan Ltd | Real estate | 2025 |
| Windmill Hill Community Centre CIC | Hospitality | 2022 |
| Winrow Group Ltd | Manufacturing | 2020 |
| Wirza&Co Limited | Wholesale & retail | 2024 |
| Wirzaa & Co Limited | Wholesale & retail | 2025 |
| WMB Logistics Ltd | Transport & logistics | 2004 |
| World of Wonder Day Nursery Ltd | Health & social care | 2025 |
| World of Wonder Playtime Ltd | Health & social care | 2023 |
| Worsall Limited | Professional & scientific | 1987 |
| WS Specialist Logistics Limited | Transport & logistics | 2014 |
| WS Tankers North West Limited | Transport & logistics | 1995 |
| WT Stores Limited | Wholesale & retail | 2026 |
| X Digital Media Ltd | Other services | 2018 |
| X-Level Competitions Ltd | Wholesale & retail | 2025 |
| X999 AGE Ltd | Construction | 2020 |
| Xactx Technical Limited | Professional & scientific | 2025 |
| XIN Chun Limited | Hospitality | 2024 |
| Xtel Technologies Group Ltd | Administrative & support | 2017 |
| Xtel Technology Solutions Ltd | Wholesale & retail | 2003 |
| Xtra Local Rvmj Convenience Store Ltd | Wholesale & retail | 2025 |
| Xtraloc Limited | Manufacturing | 1993 |
| Yannis Transport Ltd | Transport & logistics | 2015 |
| Yayb UK Limited | Wholesale & retail | 2020 |
| Yoder Shops Ltd | Wholesale & retail | 2026 |
| Yokogawa RAP Limited | Professional & scientific | 1994 |
| Yokogawa United Kingdom Limited | Manufacturing | 1986 |
| Your Gp-Nws National Watches Services Ltd | Other services | 2025 |
| Your Office & PA Ltd | Administrative & support | 2007 |
| Yumdrak Ltd | Transport & logistics | 2025 |
| Yves Holdings Limited | Real estate | 2026 |
| Zaffreai Ltd | Information & communication | 2026 |
| Zebra PEN (UK) Limited | Wholesale & retail | 1992 |
| Zecom Limited | Wholesale & retail | 2021 |
| Zentrone Limited | Manufacturing | 2025 |
| Zoll Medical UK Limited | Health & social care | 1993 |
| Zoll Ventilation Holdings Limited | Manufacturing | 2024 |