| Story Haus Holdings Ltd | Financial services | 2026 |
| Stourcliffe Investments Ltd | Real estate | 2021 |
| STR Foods Ltd | Wholesale & retail | 2025 |
| Strategic Travel Solutions Limited | Professional & scientific | 2015 |
| Strathclyde International College of Graduate Studies Ltd | Education | 2024 |
| Stratton UK Parks Ltd | Real estate | 2024 |
| Street Productions Ltd | Manufacturing | 2019 |
| Strongbuild Limited | Construction | 2014 |
| Strucktor UK Limited | Construction | 2015 |
| STS Property Group Ltd | Real estate | 2025 |
| Studio Joinery Ltd | Manufacturing | 2024 |
| Studio Supernatural Ltd | Administrative & support | 2021 |
| Studious Associates Limited | Financial services | 2015 |
| Studnia Construction Ltd | Construction | 2022 |
| Stylus Properties Limited | Real estate | 2024 |
| Stylusgrafix Ltd | Wholesale & retail | 2024 |
| Subterrane Ltd | Professional & scientific | 2018 |
| Success Adventures Ltd | Health & social care | 2025 |
| Suda Construction Limited | Construction | 2026 |
| Sug'R Ltd | Hospitality | 2025 |
| Sugi Enterprise UK Ltd | Professional & scientific | 2017 |
| Suissoil SA Ltd | Administrative & support | 2005 |
| Suite Inn Limited | Real estate | 2023 |
| Sukha Sankalpa Ltd | Real estate | 2025 |
| Suki Hygiene & Therapy Limited | Health & social care | 2019 |
| Sukoshi Sushi Ltd | Hospitality | 2023 |
| Summit Hospitality Ltd | Professional & scientific | 2025 |
| Sunakku Limited | Information & communication | 2022 |
| Sunfield Catering Limited | Hospitality | 2019 |
| Sunflower Union Limited | Administrative & support | 2006 |
| Sunningdale Sushi Limited | Hospitality | 2018 |
| Sunnybs Ltd | Construction | 2016 |
| Sunrise GPK Ltd | Financial services | 2019 |
| Sunset Skyline Ltd | Hospitality | 2025 |
| Sunshine City BOY Media Publishing Limited | Information & communication | 2020 |
| Supa Services Ltd | Information & communication | 2022 |
| Super Star Retail Limited | Wholesale & retail | 2023 |
| Superatio Holdings Ltd | Real estate | 2025 |
| Superfoodio Limited | Manufacturing | 2016 |
| Supermax International Transportation Co., Ltd | Extraterritorial | 2024 |
| Supernova Marine Service Ltd | Manufacturing | 2023 |
| Supratio Ltd | Real estate | 2025 |
| Supreme Supply Ltd | Wholesale & retail | 2021 |
| Suraay Group Ltd | Real estate | 2026 |
| Suraj Food & Wine Ltd | Wholesale & retail | 2015 |
| Sure Medics Ltd | Administrative & support | 2019 |
| Sure Swan Ltd. | Professional & scientific | 2019 |
| Surety & Dazzly Limited | Administrative & support | 2020 |
| Surrey Garden Design Ltd | Administrative & support | 2024 |
| Surrey Roof Masters Ltd | Construction | 2026 |
| Sush Estate Ltd | Real estate | 2023 |
| Sussex Land and Estates Ltd | Real estate | 2024 |
| Sussex Seawater Collective CIC | Professional & scientific | 2026 |
| Sustainable Catchment Solutions Limited | Professional & scientific | 2019 |
| Sutra Anni Ltd | Professional & scientific | 2025 |
| Sutton Accountants Limited | Professional & scientific | 2014 |
| Svea Ventures Ltd | Wholesale & retail | 2024 |
| SVS1 Consultancy Limited | Professional & scientific | 2014 |
| SW Real Estate Consultants Ltd | Real estate | 2024 |
| SW Scapes Limited | Construction | 2022 |
| Swallows South Ruislip Limited | Wholesale & retail | 2023 |
| Swan Group Investments LLP | | 2025 |
| Swans Day Nurseries Limited | Education | 2005 |
| Sweet Scents Limited | Other services | 2024 |
| Swift Carpentry Ltd | Construction | 2015 |
| Swift Construction Ltd | Construction | 2020 |
| Swift Consulting Group Ltd | Information & communication | 2023 |
| Swift Haven Ltd | Financial services | 2023 |
| Swift Reach Digital Ltd | Information & communication | 2023 |
| Swim Education Ltd | Education | 2024 |
| Swipe Tomorrow Ltd. | Information & communication | 1995 |
| Swirls at SDM Limited | Hospitality | 2019 |
| Swirls International Limited | Administrative & support | 2018 |
| Switch Desks Limited | Wholesale & retail | 2019 |
| SWM Estimating & Property Management Ltd | Real estate | 2016 |
| Swot Care Ltd | Health & social care | 2019 |
| Swot Consultancy Limited | Information & communication | 2003 |
| Syak Properties Limited | Real estate | 2022 |
| SYB Industrial Supply Co., Ltd. | Extraterritorial | 2019 |
| Sylar Trading Co., Limited | Administrative & support | 2023 |
| Symbol Industry Co., Ltd | Wholesale & retail | 2023 |
| Symptonic Ltd | Manufacturing | 2025 |
| Synth Cables Ltd | Wholesale & retail | 2019 |
| Syri Limited | Manufacturing | 2010 |
| System AI Consultations Ltd | Information & communication | 2025 |
| System AI Consulting Ltd | Information & communication | 2018 |
| System AI Services Ltd | Information & communication | 2025 |
| System AI Solutions Ltd | Information & communication | 2025 |
| T P W Rail Systems Limited | Administrative & support | 2010 |
| T Giles Leisure Ltd | Administrative & support | 2026 |
| T J C Training Solutions Limited | Information & communication | 2007 |
| T J Copping Roofing Limited | Construction | 2016 |
| T Kelly & Sons (Plant Hire) Limited | Construction | 1996 |
| T T Contractors Limited | Construction | 2011 |
| T&E Passive Fire Protection Limited | Construction | 2019 |
| T.A.Ellement & SON Limited | Other services | 1940 |
| T.B. Consult Ltd | Professional & scientific | 2018 |
| T.D. Car Services Ltd | Wholesale & retail | 2015 |
| T.Fuller Ltd | Construction | 2026 |
| T3P Ltd | Wholesale & retail | 2023 |