| Smart Business and Technology Solutions Ltd | Information & communication | 2014 |
| Smart Efficient Techno Limited | Information & communication | 2024 |
| Smart Home Developments Ltd | Construction | 2016 |
| Smart Impart Limited | Information & communication | 2024 |
| Smart LUX Ltd | Manufacturing | 2016 |
| Smart Spedition Ltd | Transport & logistics | 2021 |
| Smart UK Recovery Ltd | Wholesale & retail | 2026 |
| Smart Warranty Limited | Administrative & support | 2025 |
| Smarts and Sparks Ltd | Construction | 2019 |
| Smashdown Guys Ltd | Hospitality | 2026 |
| SME (Coffee) Limited | Hospitality | 2006 |
| SME (Hammersmith) Limited | Hospitality | 1989 |
| SME (Pizza) Limited | Hospitality | 2000 |
| SME Caterers Limited | Hospitality | 1986 |
| SME Charitable Trust | Health & social care | 2000 |
| SME Coffee (2) Ltd | Hospitality | 2011 |
| SME Coffee (3) Ltd | Hospitality | 2013 |
| SME Coffee (4) Limited | Hospitality | 2014 |
| SME Corporation (2) Limited | Hospitality | 2013 |
| SME Corporation Limited | Hospitality | 2007 |
| SME Fast Foods Limited | Hospitality | 1987 |
| SME Group Investment Ltd | Financial services | 2026 |
| SME Group PLC | Professional & scientific | 1988 |
| SME Holdings Limited | Professional & scientific | 2001 |
| SME Investments Limited | Professional & scientific | 2005 |
| SME Pizza (2) Limited | Hospitality | 2009 |
| SME Pizza (3) Ltd | Hospitality | 2011 |
| SME Pizza (4) Limited | Hospitality | 2014 |
| SME Properties Limited | Hospitality | 2005 |
| SME Restaurants Limited | Hospitality | 1988 |
| SME Trading Limited | Hospitality | 1989 |
| Smel-Ac Ltd | Construction | 2023 |
| SMH Plant Services Limited | Manufacturing | 2017 |
| Smile Doctor Limited | Health & social care | 2024 |
| Smile Teachers Ltd | Administrative & support | 2018 |
| Smile Treat Ltd | Information & communication | 2024 |
| Smith Coldham Design Limited | Professional & scientific | 2001 |
| Smiths Horseboxes Limited | Wholesale & retail | 2018 |
| Smjh Projects Ltd | Real estate | 2019 |
| SML Studios LLP | | 2011 |
| Smoke Consulting Limited | Professional & scientific | 2014 |
| Smoke Holdings Ltd | Financial services | 2025 |
| Smoke Property Limited | Real estate | 2018 |
| Smoke Real Estate LLP | | 2022 |
| Smudger Electrical Limited | Construction | 2007 |
| Smxas Ltd | Construction | 2021 |
| SN Creative Solutions Ltd | Real estate | 2026 |
| SN Global Traders Ltd | Wholesale & retail | 2017 |
| Snagtags Limited | Manufacturing | 2025 |
| Snapper Branding Limited | Professional & scientific | 2026 |
| SND Property Services Ltd | Other services | 2016 |
| Sniply Limited | Information & communication | 2023 |
| SNS UK Convenience Stores Ltd | Wholesale & retail | 2025 |
| SO Serene LDN Limited | Wholesale & retail | 2024 |
| Sober Living Ltd | Health & social care | 2023 |
| Soca Ltd | Information & communication | 2024 |
| Sociable Technology Limited | Information & communication | 2013 |
| Social Collective Ltd | Information & communication | 2020 |
| Social Housing Property Chain Ltd | Real estate | 2025 |
| Socon Ltd | Professional & scientific | 2017 |
| Soenia Ltd | Health & social care | 2021 |
| Soft Creations Ltd | Hospitality | 2026 |
| Sohal International Trader Limited | Wholesale & retail | 2023 |
| Sola Compliance Ltd | Professional & scientific | 2020 |
| Solex Scaffolding Ltd | Construction | 2025 |
| Solid Construction Limited | Construction | 2026 |
| Solid Contracting Limited | Construction | 2024 |
| Solid Timber Wood Flooring Ltd | Construction | 2018 |
| Solivagus Ltd | Wholesale & retail | 2026 |
| Solo Exports Limited | Arts & recreation | 1988 |
| Soloman & Hyder Law Ltd | Professional & scientific | 2022 |
| Solutions in Living Ltd | Construction | 2018 |
| Somiar Innovation Ltd | Professional & scientific | 2017 |
| SON Bikes Ltd | Wholesale & retail | 2021 |
| Sona Medical Consulting Ltd | Professional & scientific | 2026 |
| Sonchat Limited | Wholesale & retail | 2018 |
| Songs, Spells ETC Limited | Information & communication | 2023 |
| Sonic Monk Ltd | Real estate | 2019 |
| Sonittec Ltd | Information & communication | 2019 |
| Sonny Adam Ltd | Wholesale & retail | 2012 |
| Soober PPE Solutions Ltd | Transport & logistics | 2016 |
| Sophiesticuts Limited | Other services | 2025 |
| Sopiya Ltd | Wholesale & retail | 2016 |
| Sorathiya Limited | Hospitality | 2026 |
| SOS Roofing & Building Solutions Limited | Construction | 2019 |
| Soul Cognition Limited | Professional & scientific | 2019 |
| Soul Solutions Ltd | Information & communication | 2025 |
| Sound Elevation Ltd | Information & communication | 2024 |
| Sounlix Media Ltd | Information & communication | 2026 |
| Souq AI Ltd | Wholesale & retail | 2024 |
| South Indian Spice Co Ltd | Manufacturing | 2023 |
| South Ruislip Car Wash Limited | Wholesale & retail | 2020 |
| South Ruislip Detailing Limited | Wholesale & retail | 2024 |
| South West Oils Ltd | Water & waste | 2020 |
| Southall Storage Ltd | Real estate | 2019 |
| Southend Point Limited | Construction | 2016 |
| Southern Cross Tree Surgery Limited | Administrative & support | 2021 |
| SP Freight Limited | Transport & logistics | 2026 |
| SP Watertree Limited | Financial services | 2013 |
| Sparkwright Electrical Services Limited | Construction | 2012 |